A5101455114- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Biochemical Acid Research Studies
- Liver Disease Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Health and Lifestyle Studies
- Natural Antidiabetic Agents Studies
- Diabetes Treatment and Management
- Esophageal and GI Pathology
- Musculoskeletal pain and rehabilitation
- Aging, Health, and Disability
- Pain Mechanisms and Treatments
- Heavy Metals in Plants
- Arts and Performance Studies
- Alcohol Consumption and Health Effects
- Caveolin-1 and cellular processes
- Scientific Research and Technology
- Skin Diseases and Diabetes
- Orthopedic Surgery and Rehabilitation
- Education and Labor Relations
- Gastrointestinal Bleeding Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Vitamin C and Antioxidants Research
Consejo Nacional de Investigaciones Científicas y Técnicas
2009-2024
Universidad Nacional de La Plata
2009-2023
Bernardino Rivadavia Natural Sciences Museum
2021
Centro Científico Tecnológico - La Plata
2010-2013
Hospital Militar de Santiago
2011
Hospital Universitario de Valme
2007-2009
Complejo Hospitalario de Ourense
2007
Bambino Gesù Children's Hospital
1981-1994
In the present study, we investigated role of NADPH oxidase in F (fructose)-rich-diet-induced hepatic OS (oxidative stress) and metabolic changes, their prevention by apocynin co-administration. Wistar rats were fed for 21 days on (i) a control diet, (ii) diet plus 10% drinking water, (iii) with water (CA) (iv) (FA). Glycaemia, triglyceridaemia, NEFAs (non-esterified fatty acids) insulinaemia determined. liver, measured activity, gene protein expression; carbonyl groups, GSH TBARSs...
Dermatological diseases are one of the main causes people seeking care in Primary Health Care (PHC), often being treated by non-specialized doctors, which leads to an increase unnecessary referrals dermatologists and overload on specialized services. This scenario is, part, caused limited academic training professionals, affecting their ability diagnose treat dermatological conditions appropriately. Teledermatology appears as a promising solution optimize care, using information...
We evaluated the relative role of different regulatory mechanisms, particularly 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFK2/FBPase-2), in liver glucokinase (GK) activity intact animals with fructose-induced insulin resistance and impaired glucose lipid metabolism. measured blood glucose, triglyceride concentration, tolerance, content, GK activity, PFK2 protein gene expression fructose-rich diet (FRD) control rats. After 3 weeks, FRD rats had significantly higher levels,...
"Yerba mate" (YM), an aqueous extract of Ilex paraguariensis, has antioxidant, diuretic, cardio-protective and hypoglycaemic properties. Since its effect on the pancreatic islets remains unclear, we evaluated insulin sensitivity glucose-stimulated secretion (GSIS) in rats consuming YM or tap water (C) for 21 days. Glucose tolerance, glycemia, triglyceridemia, insulinemia, TBARS FRAP serum levels were evaluated. GSIS mRNA signaling pathway inflammatory markers measured isolated from both...
A high-fructose diet (HFD) induces murine alterations like those recorded in human prediabetes. Protective effects of isoespintanol (monoterpene isolated from Oxandra cf. xylopioides) on changes induced by HFD were evaluated. Animals maintained for 21 days with a standard (C), 10% fructose (F), and F plus (FI, 10 mg/kg, i.p.). Glycemia, triglyceridemia, total HDL-cholesterol, insulin resistance index (IRX) determined. Intraperitoneal glucose tolerance test (IGTT) was performed. In the liver,...
The aim of this work was to evaluate possible mechanisms involved in the protective effect N-acetyl-L-cysteine (NAC) on hepatic endocrine-metabolic, oxidative stress, and inflammatory changes prediabetic rats. For that, normal male Wistar rats (60 days old) were fed for 21 with 10% sucrose their drinking water 5 NAC administration (50 mg/kg, i.p.) thereafter, we determined: serum glucose, insulin, transaminases, uric acid, triglyceride levels; fructokinase glucokinase activities, glycogen...
We investigated the impact of chronic hypercorticosteronemia (due to neonatal monosodium L-glutamate, MSG, and treatment) on liver oxidative stress (OS), inflammation, carbohydrate/lipid metabolism in adult male rats. evaluated peripheral concentrations several metabolic OS markers insulin resistance indexes. In we assessed (a) (GSH protein carbonyl groups) inflammatory ( IL-1b , TNFa PAI-1 ) biomarkers (b) carbohydrate lipid metabolisms. MSG rats displayed degenerated optic nerves,...
Background and Objectives: The work was aimed to determine the chronological sequence of events triggered by a fructose-rich diet (FRD) (10% w/v in drinking water) normal rats. Material Methods: Serum parameters, liver islet markers metabolism, inflammation oxidative stress were determined weekly for 21 days. Results: At end first week, rats fed with FRD showed an early increase circulating triglycerides, fat deposit, enzymatic activity glucokinase glucose-6-phosphate dehydrogenase (G6P-DH)....
A qualidade da água é um tema crítico na agenda ambiental global, especialmente em ecossistemas urbanos, como o Igarapé do Mindu, Manaus, sob constante pressão pela urbanização. Este estudo analisou sua qualidade, refletindo dinâmicas socioambientais locais. pesquisa incluiu revisão literatura e análise de amostras pontos estratégicos. O Mindu sofre degradação significativa, impactando a biodiversidade saúde ambiental. Análises histórico-ambientais mostram fatores humanos gerando cenários...
Los efectos que provoca el cambio climático superponen grandes cambios para todas las personas, en ámbito social, ambiental y económico, mayor porcentaje ocurre una afectación zonas rurales, donde existe mayores índices de pobreza, bajos niveles educación, poco acceso al trabajo e inaccesibilidad a la salud, estableciendo baja calidad vida estas poblaciones. Las poblaciones radican frontera Ecuador-Colombia se encuentran entre los menos han contribuido problema del climático, más bien son...
Introducción La memoria colectiva se encuentra fundada en las relaciones intergeneracionales. Cada generación hace suyas enseñanzas y saberes populares de sus antepasados cuales serán cimento para futuras generaciones, traduciéndose una construcción social roles facultando con ello el empoderamiento comunidades sistemas valores. Objetivos interpretar la percepción que personas mayores presentan sobre traspaso intergeneracional su alimentación. Método Estudio exploratorio enfoque cualitativo,...