Chiara Giuffrè

ORCID: 0000-0003-0839-2670
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About
Contact & Profiles
Research Areas
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal Diseases and Treatments
  • Retinal and Optic Conditions
  • CNS Lymphoma Diagnosis and Treatment
  • Systemic Lupus Erythematosus Research
  • Retinal and Macular Surgery
  • Glaucoma and retinal disorders
  • Lymphoma Diagnosis and Treatment
  • Dermatological and Skeletal Disorders
  • Ocular Oncology and Treatments
  • Retinal Development and Disorders
  • Vasculitis and related conditions
  • Viral-associated cancers and disorders
  • Vascular Malformations Diagnosis and Treatment
  • Vascular Tumors and Angiosarcomas
  • Drug-Induced Ocular Toxicity
  • Retinal Imaging and Analysis
  • Autoimmune and Inflammatory Disorders Research
  • SARS-CoV-2 and COVID-19 Research
  • Traumatic Ocular and Foreign Body Injuries
  • Cerebrovascular and Carotid Artery Diseases
  • Ocular and Laser Science Research
  • Ocular Disorders and Treatments
  • Antioxidant Activity and Oxidative Stress
  • Multiple Myeloma Research and Treatments

Vita-Salute San Raffaele University
2015-2024

Istituti di Ricovero e Cura a Carattere Scientifico
2017-2024

Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2015-2024

Manchester Royal Eye Hospital
2022

University of Manchester
2022

Manchester Academic Health Science Centre
2022

IRCCS Ospedale San Raffaele
2016-2020

San Raffaele University of Rome
2017-2020

Azienda Ospedaliera San Gerardo
2020

Ocular Immunology and Uveitis Foundation
2019

<h3>Background/aims</h3> To describe the morphological features of choroidal neovascularisation (CNV) and to report ability optical coherence tomography angiography (OCT-A) detect presence myopic CNV by means this new technique. <h3>Methods</h3> Myopic cases were individuated from a pool patients with pathological myopia consecutively presenting between October 2015 March 2016. OCT-A images assessed for classification features, estimate sensitivity specificity. <h3>Results</h3> Thirty-six...

10.1136/bjophthalmol-2016-309162 article EN British Journal of Ophthalmology 2016-08-16

To detect the presence of MYD88 L265P mutation in aqueous humor patients with cytologically proven vitreoretinal lymphoma.Eight consecutive bilateral lymphoma (16 eyes) were prospectively evaluated. Genomic DNA was extracted from samples after paracentesis and vitreous diagnostic vitrectomy. codon 265 investigated by both amplification-refractory system polymerase chain reaction approach pyrosequencing assay all 6 patients. A control group 8 age-matched established diagnosis noninfectious...

10.1097/iae.0000000000002319 article EN Retina 2018-09-28

Hydroxychloroquine (HCQ) retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening early detection. The purpose this study is to report novel finding optical coherence tomography (OCT) abnormalities due HCQ toxicity that develop setting normal Humphrey visual field (HVF) testing.Data from patients with chronic exposure was obtained seven tertiary care retina centres. Ten HCQ-associated OCT HVF testing were identified. Detailed analysis findings...

10.1136/bjophthalmol-2018-313350 article EN British Journal of Ophthalmology 2019-02-28

In Italy, following the start of SARS-CoV-2 vaccination campaign, community pharmacies (CPs) were recruited on a voluntary basis in order to administer COVID-19 vaccines as part their activities. The aim present study was investigate knowledge, attitudes, and practices regarding infection prevention, vaccine acceptance/hesitancy towards influenza vaccinations among pharmacists operating Palermo Province. A cross-sectional conducted, with two different questionnaires administered before after...

10.3390/vaccines10030475 article EN cc-by Vaccines 2022-03-18

Peculiar retinal signs of vitreoretinal lymphoma (VRL) have been identified. However, limited information on the vitreous features VRL is available. This study aims to characterise involvement in with help multimodal imaging.In this retrospective, observational study, we reviewed charts and imaging all patients biopsy-proven seen from January 2016 April 2018 at a single referral centre. These included ultrawide-field imaging, ophthalmic ultrasonography slit-lamp photography. The main outcome...

10.1136/bjophthalmol-2018-313491 article EN British Journal of Ophthalmology 2019-02-01

Background/aims: To report our five-year experience on vitreoretinal lymphoma (VRL) as a single-center tertiary hospital. Methods: The ophthalmic, cytopathology, and onco-hematologic records of patients with VRL consecutively seen from 2014 to 2019 were reviewed. Results: Fifty-nine eyes 31 large B-cell included. Eighty-one percent has developed central nervous system at the end follow-up. Several different imaging findings noted, including vitritis, leopard spot appearance, Bruch's...

10.1080/09273948.2020.1787460 article EN Ocular Immunology and Inflammation 2020-08-26

The purpose of this study was to investigate the incidence foveal involvement in geographic atrophy (GA) secondary age-related macular degeneration (AMD), using machine learning assess importance risk factors.

10.1167/iovs.65.5.10 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2024-05-06

To analyse choroidal vascular density of affected and non-affected areas in active inactive serpiginouschoroiditis (SC) by means optical coherence tomography angiography (OCT-A).In this cross-sectional observational study, 22 eyes 11 patients diagnosed with SC were included. All underwent blue-light fundus autofluorescence (spectralis Heidelberg retinalangiography+OCT) swept-source OCT-A (AngioPlex Elite 9000 SS-OCT, Carl Zeiss Meditech) to qualitative features vessel considered affected,...

10.1136/bjophthalmol-2017-310989 article EN British Journal of Ophthalmology 2017-10-05

Purpose To describe the coincidence of perforating scleral vessels and choroidal neovascularization (CNV) in pathologic myopia. Methods Medical records multimodal imaging were reviewed from patients with CNV secondary to myopia who presented Retina Imaging Unit San Raffaele Hospital Milan between October 2015 March 2016. Main outcomes prevalence coincident overlying association position within macula neovascular activity. Results Forty-one eyes 39 (6 male, 33 female, mean age 63.7 ± 14.1...

10.5301/ejo.5000875 article EN European Journal of Ophthalmology 2017-02-24

Purpose: To describe the distinguishing features of retinitis-like lesions seen in vitreoretinal lymphoma (VRL) from viral and toxoplasma retinitis.Methods: In this multicenter, retrospective study, we reviewed charts imaging consecutive patients with VRL. The associated characteristics were assessed compared those toxoplasmic retinochoroiditis. Primary outcome measures unique VRL lesions.Results: Out 76 eyes 38 VRL, identified 6 confirmed on OCT. Distinctive massive retinal thickening,...

10.1080/09273948.2019.1648835 article EN Ocular Immunology and Inflammation 2019-09-30

Purpose: To report the clinical features and outcomes of corneal toxicity following mirvetuximab soravtansine therapy. Methods: Five patients who were treated with evaluated in our hospital for ocular symptoms during a period 5 months between December 2017 April 2018. A complete ophthalmologic examination, including anterior segment infrared reflectance (AS-IR) optical coherence tomography (AS-OCT), was performed. Results: All female (average age, 62.4 ± 5.5 years) being advanced epithelial...

10.1097/ico.0000000000001805 article EN Cornea 2018-10-30

Purpose To identify main qualitative and quantitative changes by spectral-domain optical coherence tomography (SD-OCT) in eyes with vitreoretinal lymphoma (VRL) shifting form active to remission phase, after intravitreal rituximab (IVR).Methods SD-OCT scans retrospectively assessed for: hyperreflective retinal dots (HRD), intraretinal infiltration, subretinal outer retina (OR) fuzzy borders, pigment epithelium detachments (PED).Central macular thickness (CMT) choroidal (CT) were measured....

10.1080/09273948.2019.1616769 article EN Ocular Immunology and Inflammation 2019-08-08

We report a case of ocular drug toxicity consistent with bilateral Vogt-Koyanagi-Harada (VKH) like disease in patient cutaneous melanoma treated Dabrafenib/Trametinib therapy. A 53-year-old man history metastatic melanoma, Dabrafenib/Trametinib, developed severe acute panuveitis granulomatous anterior uveitis and multiple serous retinal detachments. The inflammatory reaction was classified as disease. Intraocular inflammation resolved after discontinuation chemotherapeutic agents aggressive...

10.1177/1120672120962044 article EN European Journal of Ophthalmology 2020-10-01

To report a case of factitious self-inflicted handheld laser-induced maculopathy.A 29-year-old man presented to our clinic complaining step-wise progressive loss vision that abruptly began in his left eye but then became bilateral. He underwent comprehensive ocular examination, including visual acuity testing, biomicroscopic, dilated funduscopic structural optical coherence tomography, en face tomography angiography, fundus autofluorescence, fluorescein and indocyanine green...

10.1097/icb.0000000000000640 article EN Retinal Cases & Brief Reports 2017-09-21

To describe a case of multiple detachments the neurosensory retina mimicking multifocal vitelliform macular dystrophy after chemotherapy with mitogen/extracellular signal-regulated kinase inhibitor for metastatic ovarian cancer.Case report.A 38-year-old woman presented to our clinic eye examination before initiation trametinib. One month starting treatment, patient complained vision loss and metamorphopsia in both eyes. Best-corrected visual acuity decreased from 20/20 at baseline 20/32...

10.1097/icb.0000000000000491 article EN Retinal Cases & Brief Reports 2016-11-30
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