A5087706805- Radiology practices and education
- Advanced MRI Techniques and Applications
- Radiation Dose and Imaging
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Meningioma and schwannoma management
- Lipid metabolism and disorders
- Hemoglobinopathies and Related Disorders
- Hematological disorders and diagnostics
- Neurofibromatosis and Schwannoma Cases
- Traumatic Brain Injury and Neurovascular Disturbances
- Frailty in Older Adults
- COVID-19 diagnosis using AI
- Head and Neck Surgical Oncology
- Caveolin-1 and cellular processes
- Traumatic Brain Injury Research
- Ultrasound in Clinical Applications
- Traumatic Ocular and Foreign Body Injuries
- Orthopedic Infections and Treatments
- Erythrocyte Function and Pathophysiology
- Innovations in Medical Education
- Digital Radiography and Breast Imaging
Ashford and St Peter's Hospitals NHS Foundation Trust
2025
University of California, Los Angeles
2024-2025
University College London
2005-2024
St. Peter's Hospital
2024
Indira Gandhi Institute of Technology
2024
University College Hospital
2024
Cedars-Sinai Medical Center
2024
University of Southern California
2016-2023
St Peter's Hospital
2022
Keck Hospital of USC
2019-2020
Abstract Pseudoprogression (PsP) is a diagnostic clinical dilemma in cancer. In this study, we retrospectively analyse glioblastoma patients, and using their dynamic susceptibility contrast contrast-enhanced perfusion MRI images build classifier radiomic features obtained from both Ktrans rCBV maps coupled with support vector machines. We achieve an accuracy of 90.82% (area under the curve (AUC) = 89.10%, sensitivity 91.36%, 67 specificity 88.24%, p 0.017) differentiating between...
Background: Children with lower-limb-length discrepancy require repeated radiographic assessment for monitoring and as a guide management. The need accurate of length alignment is balanced by the to minimize radiation exposure. We compared accuracy, reliability, dose EOS, novel low-dose upright biplanar imaging system, at two different settings, that conventional radiographs (teleoroentgenograms) computed tomography (CT) scanograms, limb length. Methods: A phantom in standardized position...
<h3>BACKGROUND AND PURPOSE:</h3> Spontaneous spinal CSF leaks typically cause orthostatic headache, but their detection may require specialized and invasive imaging. We undertook a study to determine the value of simple optic nerve sheath MR imaging measurements in predicting likelihood finding CSF-venous fistula, type leak that cannot be detected with routine spine or CT myelography, among patients headache normal conventional brain findings. <h3>MATERIALS METHODS:</h3> This cohort included...
<h3>BACKGROUND AND PURPOSE:</h3> Accurate determination of glioma grade leads to improved treatment planning. The criterion standard for grading is invasive tissue sampling. Recently, radiomic features have shown excellent potential in glioma-grade prediction. These may not fully exploit the underlying information MR images. objective this study was investigate performance learned by a convolutional neural network compared with <h3>MATERIALS METHODS:</h3> A total 237 patients gliomas were...
Dysregulation of fatty acid metabolism is important in the pathogenesis type 2 diabetes. Peroxisome proliferator-activated receptor (PPAR)α a master regulator catabolism, and PPARα activators delay onset We examined association between three gene polymorphisms (an A→C variant intron 1, L162V variant, 7 G→C variant) age at diagnosis diabetes 912 Caucasian diabetic subjects. Individually, variants did not influence diagnosis, but combination, rare alleles both 1 (P &lt; 0.001) = 0.025)...
<h3>BACKGROUND AND PURPOSE:</h3> With >473,000 annual emergency department visits for children with traumatic brain injuries in the United States, risk of ionizing radiation exposure during CT examinations is a real concern. The purpose this study was to assess validity rapid MR imaging replace follow-up patients head trauma. <h3>MATERIALS METHODS:</h3> A retrospective review 103 pediatric who underwent initial and subsequent between January 2010 July 2013 performed. Patients had minor...
Abstract: Whether iron deficient RBC in humans have a reduced, or an increased, susceptibility to lipid peroxidation was studied the deficiency states of primary proliferative polycythaemia and anaemia related changes activities iron‐dependent non‐iron dependent antioxidant enzymes. Susceptibility RBCs increased when expressed per g Hb. However, this result low Hb giving membrane lipid: ratio incubations. Results were normal either cell, ml, RBC. Glutathione reductase normal. Increased...
There is a paucity of data on direct comparison clinical measures in patients with abdominal aortic aneurysm (AAA) and those peripheral arterial disease (PAD). Here, we examine the risk factors outcomes between these 2 conditions. Group differences were examined by Fisher's exact tests Bonferroni correction, postoperative complications (including delirium pneumonia) LOS logistic regression, mortality Cox adjusted for age, sex, smoking, co-morbidities medications. In total, 160 men 33 women...
Abstract Purpose To compare 0.55 T and 3 MRI for imaging patients with titanium total hip arthroplasty (THA). Patients orthopedic metallic implants often require diagnostic to evaluate adjacent tissues. performance measures, including artifact levels SNR, vary field strength. Methods Six THA were scanned similar protocols at T, proton density (PD) weighted turbo spin echo (TSE), PD TSE view‐angle tilting (TSE + VAT), slice encoding metal correction (SEMAC), short tau inversion recovery SEMAC...
Familial erythrocytosis, associated with high haemoglobin levels and low serum erythropoietin (Epo), has been shown to co‐segregate a sequence repeat polymorphism at the 5′ region of receptor (EpoR) in large Finnish family. We have investigated cause erythrocytosis an English boy. Sequencing cytoplasmic EpoR detected de novo transition mutation G A nucleotide 6002. This resulted formation stop codon amino acid 439 loss 70 acids from carboxy terminus. The (G6002A) arisen independently family...
Quantitative DCE-MRI provides voxel-wise estimates of tracer-kinetic parameters that are valuable in the assessment health and disease. These maps suffer from many known sources variability. This variability is expensive to compute using current methods, typically not reported. Here, we demonstrate a novel approach for simultaneous estimation their uncertainty due intrinsic characteristics model, with very low computation time. We train use neural network estimate approximate joint posterior...
Radiation therapy is an integral part of the standard care for many patients with brain and spine tumors. Stereotactic radiation surgery increasingly being used as adjuvant well a sole treatment. However, despite newer more focused techniques, still causes significant neurotoxicity. In this article, we reviewed scientific literature, presented cases who had developed different complications related to conventional or radiosurgery (gamma knife), demonstrated imaging findings, discussed...
The place of pulse oximetry in monitoring arterial oxygen saturation sickle cell disease has been evaluated. In four admissions patients with anaemia varying degrees haemoglobin desaturation, was compared a simultaneous assessment by blood gas measurement and dissociation curve (ODC) analysis. Close agreement found between the measured that calculated from partial pressure (PaO2) reference to patient's own ODC. Calculation analyser assuming normal ODC erroneous. Pulse is an accurate...
<h3>SUMMARY:</h3> Extracorporeal membrane oxygenation is an artificial cardiopulmonary bypass technique used to support patients with severe pulmonary failure or both and cardiac failure. The hemodynamic changes produced by extracorporeal affect the appearance of CTA head images, often confounding interpretation if correct history understanding are not known. This technical report describes principles oxygenation, techniques optimize intracranial imaging, pitfalls.
Patients with blunt and penetrating traumatic injuries to the skull base soft tissues of neck present emergency department every day. Fortunately, truly life-threatening these regions are relatively uncommon. However, when encountered not correctly diagnosed, entities may result in severe morbidity or mortality. The radiologist plays a critical role recognizing injuries, which findings often be subtle anatomy potentially challenging identify. Multisection CT angiography commonly performed...
Introduction 1.5 Tesla (1.5T) remain a significant field strength for brain imaging worldwide. Recent computer simulations and clinical studies at 3T MRI have suggested that dynamic susceptibility contrast (DSC) using 30° flip angle (“low-FA”) with model-based leakage correction no gadolinium-based agent (GBCA) preload provides equivalent relative cerebral blood volume (rCBV) measurements to the reference-standard acquisition single-dose GBCA 60° (“intermediate-FA”) correction. However, it...
Infection involving the vertebral column, including bone, intervertebral disk, and paravertebral soft tissues is critical early diagnosis directed treatment paramount. Different infectious organisms present with variable imaging characteristics, which when examined in conjunction clinical history, can facilitate ultimately prevent patient morbidity mortality. This article discusses pathophysiology of infection as well findings bacterial, tuberculous, fungal spondylitis/spondylodiskitis. We...
In Brief Objectives: We sought association of genetic variants in the renin-angiotensin system (RAS) and vitamin D with acute pancreatitis (AP) development severity. Background: The endocrine RAS is involved circulatory homeostasis through pressor action angiotensin II at its AT1 receptor. However, local regulate growth inflammation diverse cells tissues, their activity may be suppressed by D. Intrapancreatic generation has been implicated AP. Methods: Five hundred forty-four white patients...