A5107956007- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Biological and pharmacological studies of plants
- RNA Research and Splicing
- Berberine and alkaloids research
- Alkaloids: synthesis and pharmacology
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Mycorrhizal Fungi and Plant Interactions
- COVID-19 diagnosis using AI
- Lung Cancer Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- DNA Repair Mechanisms
- Cancer Genomics and Diagnostics
- Plant Molecular Biology Research
- Plant and animal studies
- Cancer, Hypoxia, and Metabolism
- Signaling Pathways in Disease
- Viral Infections and Immunology Research
- Viral Infectious Diseases and Gene Expression in Insects
- Fungal Biology and Applications
- Neuroblastoma Research and Treatments
- Virus-based gene therapy research
Dali University
2025
Northeast Forestry University
2024-2025
Fifth Tianjin Central Hospital
2024
Guangzhou Medical University
2024
Children's Hospital of Fudan University
2024
Roskilde University
2010
Berberine is an effective antimicrobial and antidiabetic alkaloid, primarily extracted from divergent botanical lineages, specifically Coptis (Ranunculales, early-diverging eudicot) Phellodendron (Sapindales, core eudicot). In comparison with its known pathway in species, biosynthesis species remains elusive. Using chromosome-level genome assembly, coexpression matrix, biochemical assays, we identified six key steps berberine amurense , including methylation, hydroxylation, bridge formation....
Summary Dendrobium devonianum , a species of the Orchidaceae family, is notable for its unique floral characteristics, which include two yellow spots and purple tips on labellum, as well fringed edges. However, molecular mechanisms underlying flower pattern formation in D. remain poorly understood, hindering advancements breeding process. Here, chromosome‐scale genome was presented first time, revealing significant polyploidization events. Additionally, high‐resolution single‐cell...
Adenoviral infections, particularly in children, remain a significant public health issue with no approved targeted treatments. Artemisinin and its derivatives, well-known for their use malaria treatment, have shown antiviral activities recent studies. However, efficacy against human adenovirus (HAdV) remains unexplored. This study aimed to assess the activity of artemisinin derivatives HAdV infection vitro using cell lines primary cells. Our data revealed that exhibited dose-dependent...
Abstract Background: Pulmonary function tests (PFTs) and computed tomography (CT) imaging are vital in diagnosing, managing, monitoring lung diseases. A common issue practice is the lack of access to recorded pulmonary functions despite available chest CT scans. Purpose: To develop validate a deep learning algorithm for predicting directly from Methods: The development cohort came Pittsburgh Lung Screening Study (PLuSS) (n=3619). validation Specialized Centers Clinically Oriented Research...
<title>Abstract</title> Objective The purpose of this study was to investigate how miR-200b-3p inhibits the proliferation and metastasis endometrial cancer cells by inducing expression FOSL2 in AP1 transcription family. Methods Endometrial cell line HEC-1-A divided into 12 groups: NC-mimic ( transfected with negative control NC mimic ), NC-suppress inhibit group si-NC Si-NC Si-FOSL2 oe-NC oe-FOSL2 MiR-200b-3p + co-transfected si-FOSL2 ). Real-time fluorescence quantitative PCR, Western blot,...