A5021966633- Abdominal vascular conditions and treatments
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Appendicitis Diagnosis and Management
- Intestinal and Peritoneal Adhesions
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Diverticular Disease and Complications
- Biliary and Gastrointestinal Fistulas
- Omental and Epiploic Conditions
- Intraperitoneal and Appendiceal Malignancies
- Neuroendocrine Tumor Research Advances
- Abdominal Trauma and Injuries
- Transplantation: Methods and Outcomes
- Renal Transplantation Outcomes and Treatments
- Advanced X-ray and CT Imaging
- Pelvic and Acetabular Injuries
- Radiation Dose and Imaging
- Colorectal Cancer Treatments and Studies
- Spine and Intervertebral Disc Pathology
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
Cliniques Universitaires Saint-Luc
2016-2025
UCLouvain
2012-2021
Ospedale di Cattinara
2021
University of Trieste
2021
Leefmilieu Brussel
2004-2018
Institut Universitaire de Recherche Clinique
2017
Weatherford College
2010
UCLouvain Saint-Louis Brussels
1997
This study assesses how the metastatic immune landscape is impacting response to treatment and outcome of colorectal cancer (CRC) patients. Complete curative resection metastases (n = 441) was performed for two patient cohorts 153). Immune densities were quantified in center invasive margin all metastases. Immunoscore T B cell (TB) score analyzed relation radiological pathological responses patient’s disease-free (DFS) overall survival (OS) using multivariable Cox proportional hazards...
<b>Background and study aims:</b> The role of endoscopic submucosal dissection (ESD) in Barrett's neoplasia is ill-defined, although it might provide a higher curative resection rate better histologic assessment than mucosal (EMR). We aimed to assess efficacy, safety, long-term results ESD. <b>Patients methods:</b> A retrospective analysis was done 75 consecutive patients with esophagus who underwent ESD between January 2007 February 2014. performed for visible lesions that were multiple,...
To evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein (PV) reconstruction, ABO compatibility, and impact maternal donation on graft acceptance.LDLT ABO-mismatched constitute feasible options to alleviate organ shortage in children. Vascular complications hypoplasia biliary atresia (BA) acute rejection (AR) are still major concerns this field.Data from 250 LDLT recipients, performed at Cliniques Universitaires Saint-Luc between July 1993 June...
Selective internal radiation therapy (SIRT) has shown good results in unresectable liver metastases from neuroendocrine neoplasms (NELM) with a high disease control rate (DCR) reported. The aims of the study is to assess retrospectively efficacy and safety 10y SIRT for NELM. Primary endpoint was objective response (ORR) DCR by RECIST 1.1 at 2, 4 12 months (m). Secondary endpoints were overall survival (OS), progressionfree (liver-PFS), clinical (NEN-related symptoms improvement) safety. 50...
Nodal stage is a strong prognostic factor of oncological outcome rectal cancer. To compensate for the variation in total number harvested nodes, calculation lymph node ratio (LNR) has been advocated. The aim study was to compare impact, on long-term outcome, LNR with other predictive factors, including quality mesorectal excision (TME) and state circumferential resection margin.Consecutive patients having elective surgery nonmetastatic cancer were extracted from prospectively maintained...
Background. The original method of liver transplantation (LT) included recipient inferior vena cava (IVC) resection and the use extracorporeal venovenous bypass (VVB). Refinements in technique permit to be done with IVC preservation without VVB use. Material Methods. Between November 1993 2000, 202 consecutive grafts were performed 188 adults (≥16 years age). Twelve patients (6.4%) received two three retransplants (re-LT). Split grafting was 19 times (19 grafts, 9.4%). Risk factors United...
Splenectomy is the only potentially curative treatment for chronic immune thrombocytopenic purpura (ITP) in adults. However, one-third of patients relapse without predictive factors identified. We evaluate value site platelet sequestration on response to splenectomy with ITP. Eighty-two consecutive ITP treated by between 1992 and 2013 were retrospectively reviewed. Platelet was studied 111Indium-oxinate-labeled platelets 93% patients. Response defined at last follow-up as: complete (CR)...
Early portal vein thrombosis is a rare but severe posttransplant complication that may lead to graft and/or patient loss. Transjugular intrahepatic portosystemic shunting and local thrombolysis represent an easy solution this major of liver transplantation.
We evaluated the combination of rituximab with chlorambucil in patients mantle cell lymphoma (MCL) not eligible for aggressive therapy. Fourteen (male/female: 9/5) were included (two newly diagnosed, 12 relapsed/refractory). The toxicities neutropenia, thrombopenia and infection. Nine (64%) responded; five (36%) achieved complete remission four (29%) partial remission. median progression-free survival responders was 26 months (95% CI, 4-48). Marrow polymerase chain reaction negativity...
Chronic pancreatitis may lead to steatorrhea, enteric hyperoxaluria, and kidney damage. However, the prevalence determinants of hyperoxaluria in chronic patients as well its association with renal function decline have not been investigated. We performed an observational study. Urine oxalate creatinine ratio was assessed on 2 independent random urine samples consecutive adult followed at outpatient clinic from March 1 October 31, 2012. Baseline characteristics annual estimated glomerular...
Optimal preoperative treatment before colorectal cancer metastases (CRCM) resection remains unclear. This study evaluated pathological responses (pR) in CRCM resected after chemotherapy alone or combined with angiogenesis epidermal growth factor receptor (EGFR) inhibitors.Pathological response was retrospectively on 264 from 99 patients. The proportion of responding different treatments reported and compared. Patient's progression-free survival (PFS) overall (OS) were compared based pR.The...
La place de la dissection sous muqueuse (ESD) dans dysplasie compliquant l'œsophage Barrett (OB) n'est pas encore définie bien que cette technique permettrait l'obtention d'un meilleur taux résection curative et d'une meilleure évaluation histologique comparés à par mucosectomie (EMR). Le but notre étude était d'évaluer l'efficacité, sécurité les résultats long terme l'ESD l'OB.
Donor safety is paramount in living organ donation. Left liver resections are considered safer than right lobe hepatectomies. However, unexpected intraoperative adverse events (iAEs), defined as any deviation from the ideal course, can also occur during left and may be life threatening or lead to postoperative complication permanent harm donor recipient.Records of 438 donors (LDs) who underwent 393 lateral sectionectomies (LLSs) 45 hepatectomies (LHs) between July 1993 December 2018 a...