A5022861225- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- RNA modifications and cancer
- Polyamine Metabolism and Applications
- Genetic Associations and Epidemiology
- Neuroscience and Neuropharmacology Research
- Amino Acid Enzymes and Metabolism
- Spinal Cord Injury Research
- Veterinary Pharmacology and Anesthesia
- Anesthesia and Neurotoxicity Research
- Neuroendocrine regulation and behavior
- Liver Disease Diagnosis and Treatment
- Stress Responses and Cortisol
- Cytokine Signaling Pathways and Interactions
- RNA Research and Splicing
- Electrochemical sensors and biosensors
- Trauma and Emergency Care Studies
- Corneal surgery and disorders
- Pain Mechanisms and Treatments
- Health and Well-being Studies
- Corneal Surgery and Treatments
- PARP inhibition in cancer therapy
- Pancreatic function and diabetes
- Saffron Plant Research Studies
University of Zanjan
2025
Shahid Bahonar University of Kerman
2025
Tehran University of Medical Sciences
2017-2024
Mazandaran University of Medical Sciences
2024
Sharif University of Technology
2019-2024
Kerman University of Medical Sciences
2024
Pasteur Institute of Iran
2017-2023
Iran University of Science and Technology
2023
Islamic Azad University, Malayer Branch
2021
Shariati Hospital
2019-2020
Preserving fertility is important in men under radiation therapy because healthy cells are also affected by radiation. Supplementation with antioxidants a controversial issue this process. Designing biocompatible delivery system containing hydrophobic to release control may solve these disagreements. Herein, bifunctional periodic mesoporous organosilica (PMO) was designed load quercetin (Quer) and its application studied on damaged induced irradiation the male reproductive system....
Background: Recent evidence suggests a decline in sperm quality due to exposure environmental toxicants. Several studies have reported the adverse effects of heavy metals on human reproductive efficiency. Objectives: This study analyzed seminal levels (lead, cadmium, and arsenic) oxidative status, evaluating their relationships with parameters men from Ahvaz, southwest Iran. Methods: Semen quality, lipid peroxidation, antioxidant enzyme activity were assessed 100 attending Narges Medical...
L- and D-amino acids have diverse functions effects on the metabolism, growth, development of plants. Ornithine (Orn) plays a main role in biosynthesis many amino acids, nicotinic alkaloids, polyamines tobacco. This investigation describes impact Orn enantiomers production distribution free, conjugated, bound polyamines, as well nicotine tobacco cells. It was recognized that metabolites differently upregulated by each enantiomer. Putrescine abundantly produced exogenous L-ornithine (L-Orn),...
Opioids show both pro- and anti-epileptogenic effects in different experimental models of epilepsy. In the present study, pentylentetrazole (PTZ)-induced seizure model was used to test hypothesis that neonatal morphine administration affects susceptibility prepubertal rats. Female rats were subcutaneously injected with either or saline on postnatal days 8-14 (P8-P14). To verify long-term effect (or saline), animals treated second time (21 mg/kg; saline) P25 P32. Morphine decreased latency...
ABSTRACT Early life exposure to opiates may affect neuropathological conditions, such as epilepsy, during adulthood. We investigated whether neonatal morphine affects pentylenetetrazol (PTZ)‐induced seizures in Male rats were subcutaneously injected with or saline on postnatal days 8–14. During adulthood, each rat was assigned 1 of the following 10 sub‐groups: saline, nicotine (0.1, 0.5, μg), atropine (0.25 oxotremorine M (0.1 mecamylamine (2 8 μg). An intrahippocampal infusion indicated...
Purpose: This study aimed to investigate seizures and anxiety-like behaviors in immature rats prenatally exposed opiate drugs.Materials methods: Pregnant were randomly divided into five groups: saline, morphine, tramadol, methadone, buprenorphine. Administrations performed intraperitoneally once a day for the last seven days of pregnancy. Neonatal subdivided ten groups, split according sex. Anxiety-like behavior was tested on postnatal (PD) 19. On PD 20, seizure induced by PTZ...
Summary Anxiety disorders are among the most common mental disorders. Drugs that often administered to manage medical problems cause rebound anxiety. The use of morphine and tramadol has increased in recent decades. In present study, effects exposure during neonatal prepubertal periods on anxiety‐like behaviours rats were investigated. Male neonate injected subcutaneously with saline, or (3–21 mg/kg) a daily basis from postnatal Day (P) 8 P14. On P22, divided into seven groups...
Abstract Increasing evidence on the association of MTHFR gene polymorphism and serum homocysteine levels with autoimmune diseases such as vitiligo has made a very interesting candidate to be evaluated in different ethnicities populations. We aimed evaluate vitamin B12 their associations C677T Iranian population. This case–control study included 104 patients 100 age‐ sex‐matched healthy control subjects. Serum were measured by chemiluminescence assay. Polymerase chain reaction‐restriction...