A5100359046- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Innovations in Medical Education
- Traffic and Road Safety
- Cancer-related gene regulation
- Microtubule and mitosis dynamics
- Nutritional Studies and Diet
- Wnt/β-catenin signaling in development and cancer
- Poisoning and overdose treatments
- Diet and metabolism studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Forensic Toxicology and Drug Analysis
- Birth, Development, and Health
- Opioid Use Disorder Treatment
- Injury Epidemiology and Prevention
- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
- Acute Lymphoblastic Leukemia research
- Sperm and Testicular Function
- Trauma and Emergency Care Studies
- Prenatal Screening and Diagnostics
- Clinical Reasoning and Diagnostic Skills
Sanofi (United States)
2023
The University of Adelaide
2022-2023
Western Michigan University
2021
Stryker (United States)
2021
Cedars-Sinai Medical Center
2015
Harbin Medical University
2014
Guangdong Medical College
2013
Sixth Affiliated Hospital of Sun Yat-sen University
2011
Sun Yat-sen University
2011
APH-1 (anterior pharynx defective) along with nicastrin and PEN-2 (presenilin enhancer) are essential components of the presenilin (PS)-dependent γ-secretase complex. There exist three murine Aph-1 alleles termed Aph-1a , Aph-1b Aph-1c that encode four distinct isoforms: APH-1aL APH-1aS derived from differential splicing APH-1b, APH-1c. To determine contributions mammalian homologs in formation functional complexes, we generated - / mice immortalized fibroblasts these embryos. Compared...
A current focus of the IVF field is non-invasive imaging embryo to quantify developmental potential. Such approaches use varying wavelengths gain maximum biological information. The impact irradiating developing with discrete light not fully understood. Here, we assess a range on embryo.Murine preimplantation embryos were exposed daily within blue, green, yellow, and red spectral bands compared an unexposed control group. Development blastocyst, DNA damage, cell number/allocation blastocyst...
This study examined the association between energy-adjusted Dietary Inflammatory Index (E-DII)-based dietary inflammatory potential and depressive symptoms (DepS) among patients with breast cancer explores whether systemic inflammation mediates this association. We assessed intake DepS in 220 by three 24 h recalls Center for Epidemiological Studies Depression Scale (CES-D), respectively, determined plasma levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin...
Dimethyl sulfoxide (DMSO) is used extensively as a permeable cryoprotectant and common solvent utilized for several water-insoluble substances. DMSO has various biological pharmacological activities; however, the effect of on mouse oocyte meiotic maturation remains unknown. In DMSO-treated oocytes, we observed abnormal MII oocytes that contained large polar bodies, including 2-cell–like during in vitro maturation. Oocyte polarization did not occur, due to absence actin cap formation spindle...
Abstract Acetyl fentanyl (AF) is a Schedule I analog that has been increasingly seen in heroin and polydrug toxicity overdoses Michigan (MI). Drug users are often unaware of the presence AF their drugs because it sold mixed into or disguised as heroin. High levels drug products can cause increased incidence overdose. This article describes data from longitudinal opioid surveillance program details 102 decedents MI who were found to have evidence postmortem blood. A large portion these also...
<h3>Objective:</h3> To report tolebrutinib's safety and efficacy at Week 120 (2.5 years) in a Phase 2b trial (NCT03889639) long-term (LTS) extension (NCT03996291). <h3>Background:</h3> findings showed brain-penetrant Bruton's tyrosine kinase inhibitor tolebrutinib was well tolerated elicited dose-dependent reductions new gadolinium-enhancing T1 new/enlarging T2 lesions participants with relapsing multiple sclerosis. <h3>Design/Methods:</h3> In LTS Part A, continued their core study dose (5,...
Abstract In IVF clinics, preimplantation genetic testing (PGT) is a common practice that involves biopsy and cryopreservation of embryos for evaluation. When fails – or required already cryopreserved multiple freeze-thaw cycles occur. Though known to impact live birth rates, the exclusive influence has not been elucidated. Here, we evaluate effect repeated on embryo health implantation potential. Blastocyst-stage murine were subjected one, two three with fresh serving as control. Outcomes...