A5086230847- Salmonella and Campylobacter epidemiology
- Epigenetics and DNA Methylation
- Bladder and Urothelial Cancer Treatments
- Viral gastroenteritis research and epidemiology
- Lymphoma Diagnosis and Treatment
- Listeria monocytogenes in Food Safety
- DNA Repair Mechanisms
- RNA modifications and cancer
- Cancer-related gene regulation
- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- MicroRNA in disease regulation
- Genetic factors in colorectal cancer
- Cancer-related molecular mechanisms research
- Vibrio bacteria research studies
- Apelin-related biomedical research
- Cancer Genomics and Diagnostics
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Bacteriophages and microbial interactions
- Biomarkers in Disease Mechanisms
- Aquaculture disease management and microbiota
- Pharmacogenetics and Drug Metabolism
- Extracellular vesicles in disease
- Diet and metabolism studies
- Paraoxonase enzyme and polymorphisms
Pamukkale University
2015-2025
Bursa Uludağ Üni̇versi̇tesi̇
2001
Campylobacter jejuni, one of the most common causes human gastroenteritis, is a thermophilic and microaerophilic bacterium. These characteristics make it fastidious organism, which limits its ability to survive outside animal hosts. Nevertheless, C. jejuni can be transmitted both humans animals via environmental pathways, especially through contaminated water. Biofilms may play crucial role in survival bacterium under unfavorable conditions. The goal this study was investigate strategies...
ABSTRACT This report describes a rapid detection procedure for salmonellae from chicken feces by the combination of tetrathionate primary enrichment (preenrichment [PE])-bacterial lysis-capillary PCR and capillary gel electrophoresis. Pure Salmonella enterica serovar Enteritidis 64K was reisolated detected after buffered peptone water nutrient broth, broth base Hajna (TTBH), (TTB) preenrichments. When same culture mixed with intestinal homogenate, bacteriological reisolation achieved only...
Apelin, a novel multifunctional peptide implicated in the regulation of cardiovascular system, including blood pressure and cardiac function control, has been postulated to be involved pathophysiology hypertension hypertensive heart disease. The aim this study was investigate, for first time, whether effects apelin's chronic application might deoxycorticosterone acetate-salt-induced rats (DOCA-salt rats). In study, 8–10-week-old male Wistar were divided into four groups: control + apelin,...
AIM:To characterize and compare genotype profiles of H pylori strains isolated from patients with chronic gastritis duodenal ulcer in western part Turkey. METHODS:A total 46 [30 (CG) 16 (DU)] who had undergone endoscopy because dyspeptic complaints were studied.The antral biopsy specimens evaluated for the presence by rapid urease test culture, determined real-time PCR. RESULTS:The cagA gene was observed 43 (93.5%)isolates.The vacA s1m2 predominant subtype, found 63.3% 68.7% isolates CG DU,...
Microribonucleic acids (microRNA/miRNA/miR-) are predicted to be useful in the early diagnosis, monitoring, and treatment of diabetic nephropathy (DN). We aimed investigate relationship DN miR-21-3p, miR-29a-3p, miR-29b-3p, miR-29c-3p, miR-126-3p, miR-129-1-3p, miR-137, miR-192-5p, miR-212-3p, miR-320c.There were 50 healthy controls 100 patients with type 2 diabetes mellitus (T2DM). The divided into three subgroups: normal mildly increased (A1, n=51), moderately (A2, n=25), severely (A3,...
The current study aimed at determining the prevalence and antimicrobial resistance profiles of thermophilic Campylobacter spp. infecting broiler chickens. A total 240 caecal samples from six slaughterhouses were examined for presence C. jejuni was detected in 40.4% (97/240) coli 12.1% (29/240). agar disc diffusion method E-test used testing susceptibility isolates. isolates most resistant to nalidixic acid (79.4%) followed by tetracycline (76.3%), ciprofloxacin (74.2%) enrofloxacin (15.5%)....
Caspase-1 is implicated in several important inflammatory diseases and controls adipocyte differentiation insulin sensitivity. Interleukin-10 (IL-10) an anti-inflammatory cytokine plays role chronic conditions. This study was planned to determine if there any relationship between IL-10 levels women with PCOS. Forty-two PCOS thirty-seven healthy were evaluated this controlled clinical study. levels, serum lipid sub-fractions, fasting glucose, other hormones (gonadotropins, androgens),...
Background: Myeloid differentiation primary response 88 (MYD88) is a common adaptor protein that responsible for signaling from several receptors; mutations in this gene may play role the pathogenesis of lymphoma. Aim: We aimed to determine MYD88 L265P mutation frequency, level expression, and their associations with clinicopathological parameters mature B-cell non-Hodgkin lymphomas (NHLs). Methods: A total 68 patients were included study. The presence was analyzed by real-time polymerase...
Aberrant methylation of promoter CpG islands is known to be a major inactivation mechanism the tumor-related genes including DNA repair genes. The objective this study was determine frequency O⁶-methylguanine methyltransferase (MGMT) gene as in nonsmall cell lung cancer (NSCLC) and analyze correlation with clinicopathological parameters age, gender, smoking status, histological subtype, clinical stage. Eighty patients NSCLC were included study. analysis performed on formalin-fixed,...
Pentraxin 3 (PTX3), a prototypical member of the long pentraxin subfamily, is evolutionarily conserved multimeric pattern recognition receptor involved in humoral component innate immune system. released when tissue stressed or damaged, and interacts with many different ligands. exerts pivotal role both as regulator an indicator inflammatory response pathogenesis diseases such sepsis, vasculitis preeclampsia. Uncontrolled considered major cause unexplained recurrent pregnancy loss (URPL). We...
Due to the heterogeneous nature of Diffuse Large B-cell Lymphoma (DLBCL), mechanisms underlying tumor development and progression have not yet been fully elucidated.This study aimed compare characteristics plasma exosomes DLBCL patients healthy individuals evaluate exosomal interactions between cell lines normal B-cells.Exosome isolation was performed using an ultracentrifugation-based protocol from 20 with controls. The expression miRNAs exosome samples analyzed a miRNA microarray. presence...
To assess the association between age-related macular degeneration (AMD) and three single nucleotide polymorphisms (SNPs) related to vascular endothelial growth factor (VEGF) gene.The patients who were diagnosed with AMD included in this prospective study. Three SNPs (rs1413711, rs2146323, rs3025033) of VEGF gene genotyped by real-time polymerase chain reaction genomic DNA isolated from peripheral blood samples 82 80 controls.The genotype frequencies rs1413711 rs2146323 not significantly...
In this study, the presence of Campylobacter jejuni in water lines commercial broiler house and its role epidemiology infection flocks was investigated. The study done three sequential previously known to be infected with C. two poultry houses different sources. identified drinking nipple swab samples water-line from both houses. Fresh fecal dropping were taken for determination jejuni-carriage. Twenty 130 isolates recovered system samples, respectively. A total 150 genotyped by pulsed-field...
Cytochrome P450 (CYP) is a heme-containing enzyme superfamily metabolizing wide variety of xenobiotics, including drugs and carcinogens. The majority CYP genes are expressed in the liver, however, some isoforms also reported for number extra hepatic tissues. We analyzed P450-2A6, -3A5 -4B1 mRNAs using realtime reverse-transcriptase polymerase chain reaction (RT-PCR) total 21 homogenized prostate tissues with or without malignancy. detected consistent expression CYP2A6 CYP3A5 all, CYP4B1...