- Graphene and Nanomaterials Applications
- Cholinesterase and Neurodegenerative Diseases
- Fullerene Chemistry and Applications
- Electrochemical sensors and biosensors
- Computational Drug Discovery Methods
- Advanced biosensing and bioanalysis techniques
- Nanoparticle-Based Drug Delivery
- Temporomandibular Joint Disorders
- Medicinal Plants and Neuroprotection
- Chemistry and Chemical Engineering
- Nanoparticles: synthesis and applications
- Orthodontics and Dentofacial Orthopedics
Franciscan University of Steubenville
2022
Universidade Franciscana
2021-2022
The tau protein is considered an important qualitative and quantitative biomarker for Alzheimer’s disease in its asymptomatic phase. In 2011, biomarkers were suggested by the National Institute on Aging-Azheimer’s Association as a new criterion early diagnosis of disease. Thus, highlighting non-existence theoretical research subject, we investigated binding interaction properties between phosphorylated theoretically modeled ligands constituted fullerol functionalized with...
O tratamento irregular de residuos industriais e o descarte inadequado lixo domestico estao entre os principais motivos que tem contribuido para uma crescente poluicao rios, corregos riachos, levando a contaminacao destes corpos aquaticos. Em adicao, processos atuais comumente aplicados purificacao agua, embora eliminem agentes patogenicos, nao sao capazes remover alguns outros tipos contaminantes como por exemplo moleculas solubilizadas baixo peso molecular, farmacos. A adsorcao atualmente...
The blood-brain barrier is one of the most difficult barriers to permeate organism, allowing only passage nutrients necessary for brain function. However, nanostructures, such as fullerol, have gained prominence by being able cross this barrier. In parallel, fluorescent radiopharmaceuticals been used in diagnosis different diseases that affect central nervous system, also having affinity with biomarker proteins Azheimer’s disease: phosphorylated tau protein. an unprecedented, work aimed...
Alzheimer's disease is a worldwide health issue, and there are currently no treatments that can stop this disease. Oxidized graphene derivatives have gained prominence in use biological systems due to their excellent physical-chemical characteristics, biocompatibility ability overcome the blood-brain barrier. Other substances highlighted those of natural origin from Amazon biome, such as tucuma, fruit whose oil has been widely studied therapeutic applications. Thus, aim study was investigate...