A5016941067- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Periodontal Regeneration and Treatments
- Tissue Engineering and Regenerative Medicine
- biodegradable polymer synthesis and properties
- Mesenchymal stem cell research
- Orthopaedic implants and arthroplasty
- 3D Printing in Biomedical Research
- Nerve injury and regeneration
- Osteoarthritis Treatment and Mechanisms
- Silk-based biomaterials and applications
- Dental Implant Techniques and Outcomes
- Magnesium Alloys: Properties and Applications
- Graphene and Nanomaterials Applications
- Knee injuries and reconstruction techniques
- Collagen: Extraction and Characterization
- Neurogenesis and neuroplasticity mechanisms
- Titanium Alloys Microstructure and Properties
- Proteoglycans and glycosaminoglycans research
- Tendon Structure and Treatment
- Metal and Thin Film Mechanics
- Polymer Surface Interaction Studies
- dental development and anomalies
- MicroRNA in disease regulation
- Dental materials and restorations
Yeditepe University
2014-2024
Engineering (Italy)
2019
Middle East Technical University
1998-2018
AT Sciences (United States)
2018
Bioengineering Center
2017
Naval Academy
2014
A large variety of approaches have been used to treat and irregular shaped bone defects with less than optimal success due material or design issues. In recent years patient specific constructs prepared by additive manufacturing provided a solution the need for shaping implants fit in surgery theater. this study, cylindrical disks poly(ε-caprolactone) (PCL) were printed fused deposition modeling modified nanohydroxyapatite (HAp) poly(propylene fumarate) (PPF) create mechanically strong...
Chordomas are locally aggressive bone tumors known to arise from the remnants of notochord. Because chordomas rare, molecular studies aimed at developing new therapies scarce and approaches needed. Chordoma cells cancer stem-like share similar characteristics, including self-renewal, differentiation, resistance chemotherapy. Therefore, it seems possible that might contain a subpopulation cells. The aim this study is determine whether be present in chordomas.In study, authors used gene...
Abstract Nanofibrous double‐layer matrices were prepared by electrospinning technique with the bottom layer formed from PCL (poly‐ε‐caprolactone)/PLLA (poly‐l‐lactic acid) nanofibers and upper PCL/Gelatin nanofibers. Bottom was designed to give mechanical strength system, whereas containing gelatin optimized improve cell adhesion. Gelatin microspheres incorporated in middle of two layers for controlled growth factor delivery. Successful fabrication blend shown spectroscopy. Scanning electron...
Chitosan-chloride (CHI) and sodium hyaluronate (HA), two semiflexible biopolymers, self-assemble to form nonstoichiometric coacervates. The effect of counterions was briefly investigated by preparing HA/CHI coacervates in either CaCl2 or NaCl solutions find only a small difference their tendency coacervate. Higher water content within attributed the chaotropic nature Ca2+ ions. This also evidenced with smaller pore sizes for NaCl. Besides, coacervation chitosan-glutamate (CHI-G) HA, dynamic...
Background: In an acute burn injury the zone of stasis is initially vital but may progress to coagulation necrosis with time. this study, salvage was aimed at by subcutaneous mesenchymal stem cell injection. Methods: Mesenchymal cells were obtained from bone marrow Sprague-Dawley rats (n = 10). Twenty received thermal on back according previously described "comb burn" model. Thirty minutes after injury, injected subcutaneously experimental group Animals in control 10) given same amount...
To investigate the effect of accelerated-set mineral trioxide aggregate (MTA) on proliferation and odontoblastic differentiation human dental pulp cell niches (DPSC).ProRoot White MTA (WMTA; Dentsply Tulsa Dental, Johnson City, TN, USA) was mixed with various additives, which included distilled water, 2.5% disodium hydrogen phosphate (Na2 HPO4 ; Merck, Darmstadt, Germany) 5% calcium chloride (CaCl2 Merck). DPSC extracted from third molars were cultured directly in culture medium. Cell...
This study has been carried out to optimise the silver (Ag) content of coating synthesised on commercially pure titanium (Cp–Ti, Grade 4) for biomedical applications by micro-arc oxidation (MAO) process. The MAO process conducted in electrolytes containing acetate (AgC2H3O2) at different concentrations between 0 and 0·002 mol L−1. When compared base electrolyte, coatings ≥0·001 L−1 AgC2H3O2 added exhibited an antibacterial efficiency 99·98% against Staphylococcus aureus (S. aureus). Detailed...
For the treatment of bone injuries and defects, when PLA 3D printer technology are combined with its features, it promises great hope in personalized treatment. The average pore size is one cornerstones success tissue engineering studies. In this study, five different scaffolds sizes ranging from 100 to 550 μm were printed using a characterized by DSC, FT-IR, BF, SEM, contact angle measurement, mechanical, degradation analysis for their structural, chemical mechanical properties....
Porous poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV) and calcium phosphateloaded collagen (CaP-Gelfix) foams were seeded with rat bone marrow stromal cells implanted into defects created in femurs to study vivo formation test their suitability for use tissue engineering. At 3 6 weeks, new was evaluated by macroscopy, radiography, dual-energy X-ray absorptiometry (DEXA), quantitative computerized tomography (QCT). Atomic contents of the implants further assessed QCT. Some...