A5050451487- Mesenchymal stem cell research
- Angiogenesis and VEGF in Cancer
- Diabetic Foot Ulcer Assessment and Management
- Analytical Chemistry and Sensors
- Cancer, Hypoxia, and Metabolism
- Adipose Tissue and Metabolism
- Plant Water Relations and Carbon Dynamics
- Combustion and flame dynamics
- Advanced Control Systems Design
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Plant Stress Responses and Tolerance
- Plant and Biological Electrophysiology Studies
- Spectroscopy and Quantum Chemical Studies
- Numerical Methods and Algorithms
- Gas Sensing Nanomaterials and Sensors
- Granular flow and fluidized beds
- Cardiovascular Disease and Adiposity
- Microfluidic and Bio-sensing Technologies
- Electrical and Bioimpedance Tomography
- Phase Equilibria and Thermodynamics
- Nonlinear Dynamics and Pattern Formation
- Quantum chaos and dynamical systems
- Digital Filter Design and Implementation
- Particle Dynamics in Fluid Flows
- Adipokines, Inflammation, and Metabolic Diseases
George Washington University
2024
Cornell University
2023-2024
Indian Institute of Technology Kharagpur
2000-2020
Baystate Medical Center
2012
A simple method for fabricating a constant phase element (CPE) has been discussed. Dependence of the angle on several physical parameters have also elaborated. Finally, fractional-order differentiator circuit constructed using CPE, and its performance compared with simulated results.
The water status of the living tissue in leaves is critical determining plant function and global exchange CO
The conventional assumption is that stomatal conductance (gs) dominates the regulation of water and carbon dioxide fluxes between leaves atmosphere. Here, a nanoreporter status at mesophyll cell surface local xylem within intact maize documents significant undersaturation vapor in outside-xylem zone (OXZ) large loss this (goxz) moderate stress (no turgor loss). ratio resistances (1/goxz)/(1/gs) serves as predictive phenotype undersaturation, non-stomatal transpiration, errors standard gas...
Abstract The water status of the living tissue in leaves between xylem and stomata (outside zone (OXZ) plays a critical role plant function global mass energy balance but has remained largely inaccessible. We resolve local relations OXZ using nanogel reporter potential (ψ), AquaDust, that enables an situ, nondestructive measurement both ψ highly localized at terminus transpiration OXZ. Working maize (Zea mays L.), these measurements reveal gradients are several folds larger than those based...
We analyze the dynamics of solute mixing and reaction in a mixing-limited reactive flow by considering transport tracer linear shear Rankine vortex. The action flow, general, achieves stretching fluid elements due to heterogeneous nature flow. A vortex exhibits not only but also folding way that brings adjacent closer at every turn. strong along tangential direction is accompanied concomitant thinning radial leading diffusive flux, which may cause material from neighboring regions interface...
Introduction: Diabetes is associated with impaired endothelial function. Studies have demonstrated that progenitor cells (EPCs) and mature (EC) are susceptible to apoptosis in hyperglycemic environment. Hyperglycemia promotes p53 gene over-expression silencing prior hyperglycemia exposure prevents cellular senescence helps vascular regeneration. Previously we shown silenced human CD34+ve cell therapy even derived secretome, helped tissue Our goal this project was test whether conditioned...
Introduction: Diabetes is associated with impaired endothelial function. Studies have demonstrated that progenitor cells (EPCs) and mature (EC) are susceptible to apoptosis in hyperglycemic environment. Hyperglycemia leads p53 gene over-expression silencing prior hyperglycemia exposure prevents cellular senescence, improves mitochondrial function helps vascular regeneration.. However, it not possible obtain sufficient quantities of secretome for therapeutic purposes from hematopoietic...
Introduction: Diabetes is associated with endothelial cell dysfunction. Studies have demonstrated that progenitor cells (EPCs) and mature (EC) are susceptible to apoptosis in hyperglycemic environment, however EPC start undergo within 48 hrs whereas ECs take upto 4 weeks. We the past shown p53 gene silencing prevents senescence hyperglycemia helps vascular regeneration. also silenced hematopoeitic CD34+ve therapy helped tissue regeneration (25mmol). Our goal was test whether conditioned...
Indoor air quality (IAQ) monitoring is quite essential to maintain healthy human life. Among different pollutants effecting IAQ, formaldehyde one toxic VOC that needs be monitored. In this work, hierarchical NiO nanostructured thin film devices are used as highly selective and sensitive sensor in presence of light. The response light was obtained 291.7% at 190 ppm with a fast time ~ 24 s recovery 42 (at formaldehyde). found specific towards compared other VOCs. optimum operating temperature...
Literature shows that EPCs contribute to increased collateral vessel formation following vaso-occlusion. However diabetes reduces EPC number and formation. We cultured human exposed them 5.5 mM (equivalent 99mg%) 20mM 360mg%, HG) glucose, which resulted in significant death within 48hrs. noted HG exposure was associated with up-regulation of P53 its downstream genes such as P21, PUMA Caspase-3. hypothesized reduction hyperglycemia is secondary P53. obtained mouse from null mice observed p53...
Diabetic kidney disease (DKD) is one of the major vascular complications diabetes, which associated with glomerulosclerosis and poor perfusion. Therefore, improving renal perfusion may help to halt or reverse injury. Here, we investigated whether transplanting mouse EPC (that has been modified by transiently silencing p53 gene using Adenovirus transduction ex-vivo), under capsule could improve angiogenesis perfusion, preventing apoptosis in a hyperglycemic milieu. Methods: First, confirmed...
We analyze the dynamics of solute mixing in a vortex flow. The transport passive tracer is considered Rankine vortex. action shear flow, general, to achieve stretching fluid elements. A flow exhibits and folding elements way which brings adjacent closer every turn. strong along direction rotation accompanied by concomitant thinning radial leading diffusive flux may cause material from neighbouring regions interface aggregate. Through Lagrangian concentration evolution technique, strip...
<p>Stretching of fluid elements by a heterogeneous flow field, such as the through porous media or geophysical flows atmospheric oceanic vortices, is known to enhance mixing rates scalar fields[1]. While mechanisms leading elongation material lines are well understood, predicting still remains challenge particularly when there reconnection (or aggregation) between several parts interface, leading, at large time, so-called coalescence regime[1][2]. In this presentation, we...
Introduction: Diabetes is associated with impaired wound healing. Studies have demonstrated that endothelial progenitor cells (EPCs) and mature human (EC) are susceptible to apoptosis in hyperglycemic environment p53 gene silencing prevents cellular senescence helps vascular regeneration. Our goal was test whether cell conditioned media obtained from silenced can also improve Methods: Ad-human-P53 (TP53)-shRNA used silence P53 Ad-scrambled-null-shRNA as control. To collect condition media,...