Amit Kunwar

ORCID: 0000-0003-1017-1527
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About
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Research Areas
  • Selenium in Biological Systems
  • Organoselenium and organotellurium chemistry
  • Genomics, phytochemicals, and oxidative stress
  • Free Radicals and Antioxidants
  • Curcumin's Biomedical Applications
  • Nanoparticle-Based Drug Delivery
  • Glutathione Transferases and Polymorphisms
  • Nanoplatforms for cancer theranostics
  • Effects of Radiation Exposure
  • Metal complexes synthesis and properties
  • Advancements in Transdermal Drug Delivery
  • Computational Drug Discovery Methods
  • Quantum Dots Synthesis And Properties
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Advanced Nanomaterials in Catalysis
  • Protein Interaction Studies and Fluorescence Analysis
  • Biochemical effects in animals
  • Sulfur Compounds in Biology
  • Retinoids in leukemia and cellular processes
  • Advanced biosensing and bioanalysis techniques
  • Surfactants and Colloidal Systems
  • Chalcogenide Semiconductor Thin Films
  • Redox biology and oxidative stress
  • Pharmacological Effects of Medicinal Plants

Homi Bhabha National Institute
2017-2025

Bhabha Atomic Research Centre
2016-2025

McGill University
2014-2025

Central University of Gujarat
2025

Bhabha Atomic Research Center Hospital
2007-2024

National Institute of Technology Manipur
2023

University of Science and Technology of China
2021

Sichuan University of Science and Engineering
2021

Army Medical University
2021

Indian Institute of Chemical Technology
2012-2021

Coumarin 6 appended Ir( iii ) photocatalysts exhibited light activated anticancer effects against cancer cells via mitochondrial depolarization driven apoptosis by inducing type-I (NADH oxidation) and type-II (ROS generation) mechanisms.

10.1039/d4qi01601g article EN Inorganic Chemistry Frontiers 2024-01-01

3,3′-Diselenodipropionic acid (DSePA), a derivative of selenocystine, has been synthesized and examined for antioxidant activity, glutathione peroxidase (GPx) cytotoxicity. The effect DSePA on membrane lipid peroxidation, release hemoglobin, intracellular K+ ion as consequence erythrocyte (red blood cells or RBCs) oxidation by free radicals generated 2,2′-azobis(2-amidinopropane) hydrochloride (AAPH) were used to evaluate the ability. Lipid hemolysis, loss in RBCs assessed, respectively,...

10.1021/tx700137a article EN Chemical Research in Toxicology 2007-09-28

The lung response to radiation exposure can involve an immediate or early reaction the challenge, including cell death and initial immune reaction, be followed by a tissue injury response, of pneumonitis fibrosis, this acute reaction. Herein, we aimed determine whether markers measured within days exposure, are correlated with responses occurring weeks later.Inbred strains mice known susceptible (KK/HIJ, C57BL/6J, 129S1/SvImJ) resistant (C3H/HeJ, A/J, AKR/J) radiation-induced pulmonary...

10.1186/s13014-015-0359-y article EN cc-by Radiation Oncology 2015-02-19

We report the construction of a non-toxic nanoassembly bovine serum albumin (BSA) protein and cucurbit[7]uril macrocycle as well its stimuli-responsive breakage with adamantylamine or pH, which restores structure recognition properties. The assembly showed efficient loading controlled release standard drug, doxorubicin (DOX), same was validated in live cells. cell viability studies documented that DOX-loaded mask cytotoxicity DOX toxicity can be revived at target on demand, triggering...

10.1002/asia.201601411 article EN Chemistry - An Asian Journal 2016-11-29

In the field of preparing cosmetic formulations, recent advances recommend usage excipients derived from biocompatible materials. this context, present study aimed to prepare and characterize curcumin-loaded Pickering emulsion for possible applications in formulation. The coconut oil which is often component skin care formulations used as oily phase. Curcumin, well known absorbing solar radiation, expected work synergistically with towards improving sun protection factor (SPF) Additionally,...

10.3390/pharmaceutics16030356 article EN cc-by Pharmaceutics 2024-03-03

Water-dispersible Pluronic stabilized Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles were developed for intracellular delivery of hydrophobic anticancer drug.

10.1039/c6ra21207g article EN RSC Advances 2016-01-01

Porphyrins, especially the 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin (TMPyP), are well-accepted as photosensitizers due to strong absorption from visible near-infrared region, good singlet oxygen quantum yields well chemical versatility, all of which can be further modulated through planned supramolecular strategies. In this study, we report construction nanorods TMPyP dye/drug with captisol [sulfobutylether-β-cyclodextrin (SBE7βCD)] macrocycle host-guest interaction. The availability...

10.3389/fchem.2019.00452 article EN cc-by Frontiers in Chemistry 2019-06-21
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