A5101566878- Skin Protection and Aging
- melanin and skin pigmentation
- Pharmacological Effects of Natural Compounds
- Advanced Breast Cancer Therapies
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Bioactive Compounds
- Biocrusts and Microbial Ecology
- Biochemical Analysis and Sensing Techniques
- Colorectal Cancer Treatments and Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Wound Healing and Treatments
- Olfactory and Sensory Function Studies
- Natural product bioactivities and synthesis
- Public Health and Nutrition
Sungkyunkwan University
2011-2023
Samsung Medical Center
2011-2023
UVB irradiation can induce generation of reactive oxygen species (ROS) that cause skin aging or pigmentation. Lactobacillus acidophilus is a well-known probiotic strain regulates health through antimicrobial peptides and organic products produced by metabolism immune responses. In this study, we investigated the antioxidative, antiwrinkle, antimelanogenesis effects tyndallized KCCM12625P (AL). To analyze AL on UV irradiation-induced wrinkle formation in vitro, human keratinocytes dermal...
Loliolide is a monoterpenoid hydroxylactone present in freshwater algae that has anti-inflammatory and antiaging activity; however, its effects on ultraviolet-damaged skin have yet to be elucidated. This study investigated the antiapoptosis wound-healing of loliolide using HaCaT cells (a human keratinocyte cell line). inhibited expression reactive oxygen species (ROS) induced by ultraviolet radiation as well wrinkle formation-related matrix metalloproteinase genes increased damage...
Theasinensin A (TSA) is a major group of catechin dimers mainly found in oolong tea and black tea. This compound also manufactured with epigallocatechin gallate (EGCG) as substrate refined after the enzyme reaction. In previous studies, TSA has been reported to be effective against inflammation. However, effect these substances on skin melanin formation remains unknown. this study, we unraveled role melanogenesis using mouse melanoma B16F10 cells normal human epidermal melanocytes (NHEMs)...
The aim of this study was to investigate the efficacy Prasiola japonica ethanol extract (Pj-EE) in various mouse inflammation models. For edema mice models, eight-week-old female ICR were orally administrated with Pj-EE (25 and 50 mg/kg) for one week, before ear induction carrageenan or xylene. weight, thickness, volume paw decreased Pj-EE-treated after 3 h induction. mRNA expression levels iNOS, COX-2, IL-6, IL-1β, IFN-γ conditions. phosphorylation forms IκBα IKKα/β suppressed by at mg/kg....
The Licania genus has been used in the treatment of dysentery, diabetes, inflammation, and diarrhea South America. Of these plants, strong anti-inflammatory activity macrocarpa Cuatrec (Chrysobalanaceae) reported previously. However, beneficial activities this plant on skin health have remained unclear. This study explores protective a methanol extract (50-100 μg/mL) aerial parts L. (Lm-ME) its mechanism, terms moisturizing/hydration factors, wrinkles, UV radiation-induced cell damage,...
This retrospective multicenter real-world study aims to investigate the potential prognostic value of AEs in HCC patients treated with AB first-line setting. The study's population consisted 823 from five countries (Italy, Germany, Portugal, Japan, and Republic Korea) between October 2018 April 2022. Median overall survival (OS) was 15.9 months median progression-free (PFS) 7.6 months. 73.3% presented at least one AE during period. most common were proteinuria (29.6%), arterial hypertension...