Rafael Harpaz

ORCID: 0000-0003-1024-057X
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About
Contact & Profiles
Research Areas
  • Herpesvirus Infections and Treatments
  • Bartonella species infections research
  • Acne and Rosacea Treatments and Effects
  • Virology and Viral Diseases
  • Vaccine Coverage and Hesitancy
  • Poxvirus research and outbreaks
  • Cytomegalovirus and herpesvirus research
  • Hepatitis Viruses Studies and Epidemiology
  • Vector-borne infectious diseases
  • SARS-CoV-2 and COVID-19 Research
  • Syphilis Diagnosis and Treatment
  • Rheumatoid Arthritis Research and Therapies
  • Hepatitis B Virus Studies
  • Autoimmune and Inflammatory Disorders Research
  • Dermatology and Skin Diseases
  • Influenza Virus Research Studies
  • Vector-Borne Animal Diseases
  • Animal Virus Infections Studies
  • Urticaria and Related Conditions
  • Rabies epidemiology and control
  • Data-Driven Disease Surveillance
  • Viral gastroenteritis research and epidemiology
  • Healthcare and Venom Research
  • Systemic Lupus Erythematosus Research
  • Immune responses and vaccinations

American College of Rheumatology
2021-2022

United States Public Health Service
2021

National Center for Immunization and Respiratory Diseases
2011-2020

Centers for Disease Control and Prevention
2011-2020

AID Atlanta
2013-2019

Merck (Japan)
2016

Los Angeles County Department of Public Health
2016

The Centers
2016

Children's Hospital Colorado
2014

University of Colorado Denver
2014

On October 20, 2017, Zoster Vaccine Recombinant, Adjuvanted (Shingrix, GlaxoSmithKline, [GSK] Research Triangle Park, North Carolina), a 2-dose, subunit vaccine containing recombinant glycoprotein E in combination with novel adjuvant (AS01

10.15585/mmwr.mm6703a5 article EN MMWR Morbidity and Mortality Weekly Report 2018-01-25

Overall, the prevalence of illness attributable to vaccine-preventable diseases is greater among adults than children. Adults are recommended receive vaccinations based on their age, underlying medical conditions, lifestyle, prior vaccinations, and other considerations. Updated vaccination recommendations from CDC published annually in U.S. Adult Immunization Schedule. Despite longstanding for use many vaccines, coverage low.August 2013-June 2014 (for influenza vaccination) January-December...

10.15585/mmwr.ss6501a1 article EN MMWR Surveillance Summaries 2016-02-03

Overall, the prevalence of illness attributable to vaccine-preventable diseases is greater among adults than children. Adults are recommended receive vaccinations based on their age, underlying medical conditions, lifestyle, prior vaccinations, and other considerations. Updated vaccination recommendations from CDC published annually in U.S. Adult Immunization Schedule. Despite longstanding for use many vaccines, coverage low.August 2014-June 2015 (for influenza vaccination) January-December...

10.15585/mmwr.ss6611a1 article EN MMWR Surveillance Summaries 2017-05-04

immunosuppression increased with age, in parallel the epidemiology of prevalent conditions that require immunosuppressive treatments, but it is unclear why peaked at ages 50 to 59 years.The study has limitations.Self-reports are prone misclassification, modest range results sensitivity analyses provides reassurance regarding potential influence erroneous responses.With a limited number survey questions, causes or subsets could not be reliably determined.It unknown whether data from 2013...

10.1001/jama.2016.16477 article EN JAMA 2016-10-28

To provide guidance to rheumatology providers on the use of coronavirus disease 2019 (COVID-19) vaccines for patients with rheumatic and musculoskeletal diseases (RMDs). A task force was assembled that included 9 rheumatologists/immunologists, 2 infectious specialists, public health physicians. After agreeing scoping questions, an evidence report created summarized published literature publicly available data regarding COVID-19 vaccine efficacy safety, as well other in RMD patients. Task...

10.1002/art.41928 article EN Arthritis & Rheumatology 2021-08-04

Objective To provide guidance to rheumatology providers on the use of coronavirus disease 2019 (COVID‐19) vaccines for patients with rheumatic and musculoskeletal diseases (RMDs). Methods A task force was assembled that included 9 rheumatologists/immunologists, 2 infectious specialists, public health physicians. After agreeing scoping questions, an evidence report created summarized published literature publicly available data regarding COVID‐19 vaccine efficacy safety, as well other in RMD...

10.1002/art.41877 article EN Arthritis & Rheumatology 2021-06-15

To provide guidance to rheumatology providers on the use of COVID-19 vaccines for patients with rheumatic and musculoskeletal diseases (RMDs).A task force was assembled that included 9 rheumatologists/immunologists, 2 infectious specialists, public health physicians. After agreeing scoping questions, an evidence report created summarized published literature publicly available data regarding vaccine efficacy safety, as well other in RMD patients. Task members rated their agreement draft...

10.1002/art.42372 article EN Arthritis & Rheumatology 2022-11-08

Although about 1 percent of surgeons are infected with hepatitis B virus (HBV), transmission from to patients is thought be uncommon. In July 1992, a 47-year-old woman became ill acute after undergoing thymectomy in which thoracic-surgery resident who had six months earlier assisted.To determine whether the surgeon transmitted HBV this patient and others, we conducted chart reviews, interviews, serologic testing at two hospitals where worked 1991 1992. Hepatitis surface antigen (HBsAg)...

10.1056/nejm199602293340901 article EN New England Journal of Medicine 1996-02-29

Background. Herpes zoster (HZ) is caused by reactivation of latent varicella virus and often associated with substantial pain disability. Baseline incidence HZ prior to introduction vaccine not well described, it unclear whether the vaccination program in 1995 has altered epidemiology HZ. We examined trends impact on using a large medical claims database. Methods. Medical data from MarketScan® databases were obtained for 1993-2006. calculated all persons first outpatient service 053.xx code...

10.1093/cid/ciq077 article EN Clinical Infectious Diseases 2011-01-09

Objective: To evaluate the economic impact of routine US childhood immunization schedule: diphtheria

10.1001/archpedi.159.12.1136 article EN Archives of Pediatrics and Adolescent Medicine 2005-12-01

By 2005, vaccination had reduced the annual incidence of mumps in United States by more than 99%, with few outbreaks reported. However, 2006, a large outbreak occurred among highly vaccinated populations States, and similar have been reported worldwide. The described this report U.S. Orthodox Jewish communities during 2009 2010.Cases salivary-gland swelling other symptoms clinically compatible were investigated, demographic, clinical, laboratory, data evaluated.From June 28, 2009, through...

10.1056/nejmoa1202865 article EN New England Journal of Medicine 2012-10-31

Background. Temporal increases in the incidence of herpes zoster (HZ) have been reported but studies examined short study periods, and cause increase remains unknown. We long-term trend HZ. Methods. A population-based cohort was conducted Olmsted County, Minnesota, using data from 1945–1960 1980–2007. Medical records review possible cases performed to confirm incident HZ, patient's immune status, prescribing antivirals for relative change temporal rates before after introduction varicella...

10.1093/cid/ciw296 article EN Clinical Infectious Diseases 2016-05-08

Introduction of a universal varicella vaccine program for U.S. children in 1996 sparked concern that less-frequent exposure to would decrease external boosting immunity zoster virus and thereby increase incidence herpes (HZ).To determine whether the vaccination has influenced trends HZ population older than 65 years.Retrospective study Medicare claims.Medicare, 1992 through 2010.2 848 765 beneficiaries years.Annual from 2010; rate ratios (RRs) by age, sex, race or ethnicity; state-level...

10.7326/0003-4819-159-11-201312030-00006 article EN Annals of Internal Medicine 2013-12-02

Understanding long-term effectiveness of herpes zoster (HZ) vaccine is critical for determining policy. 176 078 members Kaiser Permanente ≥60 years vaccinated with HZ and three matched unvaccinated were included. Hazard ratios 95% confidence intervals (CIs) associated vaccination at each year following estimated by Cox regression model. The decreased from 68.7% (95% CI, 66.3%–70.9%) in the first to 4.2% −24.0% 25.9%) eighth year. This rapid decline suggests that a revaccination strategy may...

10.1093/infdis/jiw047 article EN The Journal of Infectious Diseases 2016-02-09

More than 25 million adults in the United States have chronic pain. Chronic pain has been associated with suicidality, but previous studies primarily examined nonfatal suicidal behaviors rather suicide deaths or characteristics of such deaths.

10.7326/m18-0830 article EN Annals of Internal Medicine 2018-09-12

Varicella vaccination can have complex direct and indirect influences on the epidemiology of herpes zoster among children. We evaluated pediatric trends using administrative databases. The incidence has declined in a step-wise pattern since varicella program's introduction, suggesting that rates may eventually decline entire population.

10.1093/cid/ciy954 article EN Clinical Infectious Diseases 2018-11-17
A. Blythe Ryerson Daniel J. Lang Mohammed Alazawi Milagros Neyra Dustin Hill and 95 more Kirsten St. George Meghan Fuschino Emily Lutterloh Bryon Backenson Samuel Rulli Patricia Schnabel Ruppert Jacqueline Lawler Nancy McGraw Andrew Knecht Irina Gelman Jane R. Zucker Enoma Omoregie Sarah Kidd David E. Sugerman Jaume Jorba Nancy Gerloff Terry Fei Fan Ng Adriana Lopez Nina B. Masters Jessica Leung Cara C. Burns Janell Routh Stephanie R. Bialek M. Steven Oberste Eli S. Rosenberg Bridget J. Anderson Noelle Anderson Jed A. Augustine Megan E. Baldwin Kelly M. Schiabor Barrett Ursula Bauer Andrew Beck Hanen Belgasmi Lydia J. Bennett Achal Bhatt Debra Blog Heather Boss Isaac Ravi Brenner Barrett Brister Travis Wayne Brown Tavora Buchman James E. Bullows Kara Connelly Blaise Cassano Christina J. Castro Cynthia Cirillo G. Cone Janine Cory Amina Dasin Adina de Coteau Anny DeSimone Francoise Chauvin Cynthia Dixey Kathleen Dooling Shawn Doss Christopher Duggar Christopher N. Dunham Delia Easton Christina Egan Brian Emery Randall English Nicola Faraci Hannah E. Fast G. Stephanie Feumba N. W. Fischer Stephen A. Flores Ann D. Frolov Halle Getachew Brittany Gianetti Alejandro Godinez Todd Gray William J. Gregg Christina Gulotta Sarah Hamid Tiffany Hammette Rafael Harpaz Lia Haynes Smith Brianna Hanson Elizabeth Henderson Eugene Heslin Alexandra Hess Dina Hoefer Jonathan Hoffman Lyndsey Hoyt Scott Hughes Anna R. Hutcheson Tabassum Z. Insaf Christopher Ionta Stacey Jeffries Miles Anita Kambhampati Haley R. Kappus-Kron Genevieve N. Keys Michael Kharfen Gimin Kim Jenna Knox

§ A VDPV is a strain related to the attenuated live poliovirus contained in OPV.VDPV2s are OPV virus strains that >0.6%divergent (or at least six nucleotide changes) from OPV2 complete VP1 genomic region.https://polioeradication.org/wp-content/uploads/2016/09/ Reporting-and-Classification-of-VDPVs_Aug2016_EN.pdf ¶ The term PV2, referring all serotype 2 polioviruses, used throughout report indicate either confirmed VDPV2 or type Sabin-like genetically Rockland County patient.A one of Sabin...

10.15585/mmwr.mm7144e2 article EN MMWR Morbidity and Mortality Weekly Report 2022-10-28

An immunization assessment and a serologic survey were conducted to evaluate the effectiveness of hepatitis B program in eliminating virus (HBV) transmission among Alaska Natives region which HBV infection is endemic. Hepatitis vaccine coverage was 93% 567 children </=10 years old residing study villages, catch-up 582 susceptible persons 11-30 62%. None 271 tested chronically infected with HBV, just 4 (1.5%) had evidence resolved infection. In contrast, 16% 332 (those born before...

10.1086/315259 article EN The Journal of Infectious Diseases 2000-02-01
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