Hui Yu Koh

ORCID: 0000-0003-1031-1630
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About
Contact & Profiles
Research Areas
  • Spinal Fractures and Fixation Techniques
  • Scoliosis diagnosis and treatment
  • Pelvic and Acetabular Injuries
  • Spine and Intervertebral Disc Pathology
  • Asthma and respiratory diseases
  • Tissue Engineering and Regenerative Medicine
  • Peptidase Inhibition and Analysis
  • Dermatology and Skin Diseases
  • Cardiac Structural Anomalies and Repair
  • Management of metastatic bone disease
  • Allergic Rhinitis and Sensitization

University of Hong Kong
2017-2020

National University of Singapore
2015-2016

National University Health System
2016

Bracing has been shown to decrease significantly the progression of high-risk curves threshold for surgery in patients with adolescent idiopathic scoliosis (AIS), but treatment failure rate remains high. There is evidence suggest that Schroth scoliosis-specific exercises can slow mild scoliosis. The aim this study was evaluate efficacy AIS during bracing.A prospective, historical cohort-matched carried out. Patients diagnosed who fulfilled Scoliosis Research Society (SRS) criteria bracing...

10.1186/s13013-017-0139-6 article EN cc-by Scoliosis and Spinal Disorders 2017-09-11

Aims The purpose of this study was to evaluate the incidence and analyze trends surgeon-reported complications following surgery for adolescent idiopathic scoliosis (AIS) over a 13-year period from Scoliosis Research Society (SRS) Morbidity Mortality database. Methods All patients with AIS between ten 18 years age, entered into SRS database 2004 2016, were analyzed. perioperative evaluated correlations associated factors. Complication analyzed by comparing cohorts 2007 2013 2016. Results...

10.1302/0301-620x.102b4.bjj-2019-1371.r1 article EN The Bone & Joint Journal 2020-03-31

Background: Although scoliosis is a 3-dimensional (3D) deformity, little research has been performed on the use of 3D imaging in brace curve correction. The purpose present study was to determine effect axial-plane parameters outcomes bracing with thoracolumbosacral orthosis for adolescent idiopathic scoliosis. Methods: This prospective longitudinal cohort included patients who fulfilled criteria according Scoliosis Research Society, and conducted from time patient began wearing through...

10.2106/jbjs.20.00267 article EN cc-by-nc-nd Journal of Bone and Joint Surgery 2020-10-16

Abstract Previous studies have highlighted the importance of lung-draining lymph nodes in respiratory allergic immune response, whereas lung parenchymal system has been largely neglected. We describe a new vivo model sensitization to Blomia tropicalis, principal asthma allergen tropics, which response is focused on parenchyma by transfer Th2 cells from novel TCR transgenic mouse, specific for major B. tropicalis Blo t 5, that targets rather than draining nodes. Transfer highly polarized CD4...

10.4049/jimmunol.1502676 article EN The Journal of Immunology 2016-10-13

Study Design. Retrospective study with prospective radiographic data collection. Objective. To compare fusion level determination criteria using the fulcrum bending radiograph (FBR) and last substantially touched vertebra (STV) as lowest instrumented (LIV) in outcomes of correction surgery for Lenke 1A 2A scoliosis patients a minimum 2-year follow-up. Summary Background Data. The STV has been proposed LIV curves to avoid postoperative distal adding-on. However, influence inherent flexibility...

10.1097/brs.0000000000003182 article EN Spine 2019-08-06

Abstract Patients with severe asthma are very difficult to manage present a major medical challenge. Development of clinical requires many years patient exposure allergens. Mouse models require weeks and normally transitory do not lead allergen-induced dyspnea. We have followed an alternative approach conventional immunization through the transfer highly polarized CD4 T cell receptor transgenic cells specific for dust mite allergen Blo t 5 by thrice weekly intranasal recombinant challenge...

10.4049/jimmunol.194.supp.53.8 article EN The Journal of Immunology 2015-05-01
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