Kartik M. Varadarajan

ORCID: 0000-0003-1039-3314
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About
Contact & Profiles
Research Areas
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Knee injuries and reconstruction techniques
  • Orthopedic Infections and Treatments
  • Lower Extremity Biomechanics and Pathologies
  • Hip disorders and treatments
  • Additive Manufacturing and 3D Printing Technologies
  • Advanced X-ray and CT Imaging
  • Bone Tissue Engineering Materials
  • Advanced Sensor and Energy Harvesting Materials
  • Sports injuries and prevention
  • Electrical and Bioimpedance Tomography
  • Conducting polymers and applications
  • Foot and Ankle Surgery
  • Hip and Femur Fractures
  • Osteoarthritis Treatment and Mechanisms
  • Material Dynamics and Properties
  • Muscle activation and electromyography studies
  • Graphene and Nanomaterials Applications
  • Advanced Measurement and Metrology Techniques
  • Shoulder Injury and Treatment
  • Body Composition Measurement Techniques
  • Robotics and Sensor-Based Localization
  • Advanced machining processes and optimization
  • Advanced Surface Polishing Techniques

Massachusetts General Hospital
2015-2024

Harvard University
2012-2024

Boston Medical Center
2023

University Medical Center
2023

Boston University
2023

Lemuel Shattuck Hospital
2018-2020

Harvard University Press
2020

Rothman Orthopaedics
2015

TU Wien
2010-2011

Royal Alexandra Children's Hospital
2011

The study is focused on multifunctional performance of carbon nanotubes (CNT) and Graphene nanoplatelets (GNP) reinforced PEEK composites enabled via fused filament fabrication (FFF) additive manufacturing (AM) utilizing in-house nanoengineered filaments. Thermo-physical, mechanical wear characteristics electro-conductive nanocomposites are reported. coefficient thermal expansion (CTE) found to decrease by 26% 18% with the incorporation 5 wt% GNP 3 CNT into polymer, respectively. in CTE...

10.1016/j.compositesb.2019.107625 article EN cc-by-nc-nd Composites Part B Engineering 2019-11-27

Anti-bacterial scaffolds made of copper, bronze and silver particles filled PLA nanocomposites were realized via fused filament fabrication (FFF), additive manufacturing. The thermal, mechanical biological characteristics including bioactivity bactericidal properties the evaluated. incorporation into neat increases elastic modulus up to 10% 27% for samples printed in 0° 90° configurations respectively. stiffness increases, 103% nanocomposite scaffolds. surface was treated with acetic acid...

10.1016/j.jmbbm.2019.103576 article EN cc-by-nc-nd Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2019-12-03

Identifying the design of a failed implant is key step in preoperative planning revision total joint arthroplasty. Manual identification from radiographic images time-consuming and prone to error. Failure identify preoperatively can lead increased operating room time, more complex surgery, blood loss, bone recovery overall healthcare costs. In this study, we present novel, fully automatic interpretable approach hip replacement (THR) implants plain radiographs using deep convolutional neural...

10.1002/jor.24617 article EN Journal of Orthopaedic Research® 2020-01-30

Abstract Background Postoperative complications continue to constitute a major issue for both the healthcare system and individual patient are associated with inferior outcomes higher costs. The objective of this study was evaluate trends postoperative complication rates over 7-year period. Methods NSQIP datasets from 2012 2018 were used assess 30-day incidence including mortality rate following surgical procedures within ten subspecialties. Multivariable logistic regression associate...

10.1186/s12893-021-01392-z article EN cc-by BMC Surgery 2021-11-06

BackgroundEarly detection of postoperative complications, including organ failure, is pivotal in the initiation targeted treatment strategies aimed at attenuating damage. In an era increasing health-care costs and limited financial resources, identifying surgical patients a high risk complications providing personalised precision medicine-based provides obvious pathway for reducing patient morbidity mortality. We to leverage deep learning create, through training on structured electronic...

10.1016/s2589-7500(21)00084-4 article EN cc-by-nc-nd The Lancet Digital Health 2021-06-29

We present carbon nanotube (CNT)-reinforced polypropylene random copolymer (PPR) nanocomposites for the additive manufacturing of self-sensing piezoresistive materials via fused filament fabrication. The PPR/CNT feedstock filaments were synthesized through high shear-induced melt blending with controlled CNT loading up to 8 wt % enable three-dimensional (3D) printing nanoengineered composites. CNTs found enhance crystallinity (up 6%) in PPR-printed parts, contributing overall...

10.1021/acsami.1c20491 article EN ACS Applied Materials & Interfaces 2022-02-04

This study is focused on carbon nanostructures (CNS), including both nanotubes (CNTs) and graphene nanoplatelets (GNPs), reinforcement of medical‐grade polyetheretherketone (PEEK), in vitro bioactivity for biomedical structural applications. CNS/PEEK scaffolds bulk specimens, realized via fused filament fabrication (FFF) additive manufacturing, are assessed primarily the low‐strain linear‐elastic regime. 3D printed PEEK nanocomposites found to have enhanced mechanical properties all cases...

10.1002/adem.202000483 article EN cc-by Advanced Engineering Materials 2020-07-09

Trochlear dysplasia is a known risk factor for patellar instability. Multiple radiographic measurements exist to assess trochlear morphology, but the optimal measurement technique and threshold instability are unknown.To describe thresholds on magnetic resonance imaging (MRI) that can identify knees with in male female patients.Cohort study (diagnosis); Level of evidence, 3.Knee MRI scans patients were compared those age- sex-matched controls. Measurements sulcus angle, lateral inclination...

10.1177/03635465231158099 article EN The American Journal of Sports Medicine 2023-03-21

Abstract Knowledge of the morphology and kinematics male female knees is important for understanding gender‐related dimorphism in knee pathology improvement related surgical treatments. Twelve 12 subjects with healthy were recruited, each subject performed a single leg lunge while images recorded by two fluoroscopes. Tibiofemoral joint motion was then reproduced using bony models matched to fluoroscopic images. Femoral trochlear groove orientation also measured knee. While many parameters...

10.1002/jor.20844 article EN Journal of Orthopaedic Research® 2009-01-06

Total knee arthroplasty (TKA) is a widely accepted surgical procedure for the treatment of patients with end-stage osteoarthritis (OA). However, function not always fully recovered after TKA. We used dual fluoroscopic imaging system to evaluate in vivo kinematics medial compartment OA before and posterior cruciate ligament-retaining TKA (PCR-TKA) during weight-bearing flexion, compared results those normal knees. The knees displayed similar internal/external tibial rotation had less overall...

10.1002/jor.21203 article EN Journal of Orthopaedic Research® 2010-07-07

Biomaterials associated infection (BAI) has been identified as one of the leading causes failure bioimplants. A failed implant requires revision surgery, which is about 20 times costlier and more painful than primary surgery. Infection starts from initial attachment bacteria onto surface biomaterials followed by colonization biofilm formation. Once a developed become resistant toward antibiotics. On account microbial cell development, their metabolic activity viability are strongly affected...

10.1021/acsbiomaterials.9b00213 article EN ACS Biomaterials Science & Engineering 2019-03-18

Abstract Herein, we report the physicochemical, thermal, mechanical and biological characteristics, including bioactivity, biodegradation cytocompatibility of additive manufacturing-enabled novel nanocomposite scaffolds. The scaffolds comprise a blend polylactic acid (PLA) poly-ε-caprolactone (PCL) reinforced with halloysite nanotubes (HNTs). nanoengineered filaments were developed by melt blending, manufactured fused filament fabrication. Uniform dispersion HNTs in PLA/PCL is revealed via...

10.1007/s10853-021-06145-0 article EN cc-by Journal of Materials Science 2021-05-27
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