A5079465075- Neuroinflammation and Neurodegeneration Mechanisms
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Microbial Natural Products and Biosynthesis
- Cancer Mechanisms and Therapy
- Alkaloids: synthesis and pharmacology
- RNA modifications and cancer
- Tryptophan and brain disorders
- Cancer therapeutics and mechanisms
Beijing University of Chinese Medicine
2022-2025
Beijing Fengtai Hospital
2022
Huayu Wan (HYW), a traditional Chinese medicine prescription widely used in the clinical treatment of advanced lung cancer, has been clinically proven to effectively inhibit progression pulmonary tumors and improve patients' quality life. However, its specific components potential anti-cancer molecular mechanisms remain unclear. To explore active ingredients HYW predict effective targets pathways against non-small cell cancer (NSCLC) using combination network pharmacology transcriptomics....
Chordin-like 1 (CHRDL1) is a secreted antagonist of bone morphogenetic proteins, and has been implicated in various biological processes cancer prognosis. This study offered detailed examination CHRDL1 expression across 33 diverse types, leveraging data from The Cancer Genome Atlas (TCGA) supplementary public datasets. We demonstrated that, for the majority was reduced tumor tissues compared to normal adjacent tissues. Notably, lower led negative prognosis malignancies such as lung...