- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- Calcium Carbonate Crystallization and Inhibition
- Dental Implant Techniques and Outcomes
- biodegradable polymer synthesis and properties
- Graphene and Nanomaterials Applications
- Dental materials and restorations
- 3D Printing in Biomedical Research
- Titanium Alloys Microstructure and Properties
- High-Temperature Coating Behaviors
- Facial Trauma and Fracture Management
- Electron and X-Ray Spectroscopy Techniques
- Nanoplatforms for cancer theranostics
- Orthodontics and Dentofacial Orthopedics
- Additive Manufacturing Materials and Processes
- Orthopaedic implants and arthroplasty
- Glass properties and applications
- Endodontics and Root Canal Treatments
- Thermal and Kinetic Analysis
Universitatea Națională de Știință și Tehnologie Politehnica București
2015-2024
Center of Technology and Engineering for Nuclear Projects
2017-2019
The successful regeneration of large-size bone defects remains one the most critical challenges faced in orthopaedics. Recently, 3D printing technology has been widely used to fabricate reliable, reproducible and economically affordable scaffolds with specifically designed shapes porosity, capable providing sufficient biomimetic cues for a desired cellular behaviour. Natural or synthetic polymers reinforced active bioceramics and/or graphene derivatives have demonstrated adequate mechanical...
Calcium phosphates (CPs) used as biomaterials have been intensively studied in recent years. In most studies, the determination of chemical composition is mandatory. Due to versatility and possibilities performing qualitative quantitative compositional analyses, energy dispersive spectrometry (EDS) a widely technique this regard. The range calcium very diverse, first method approximating type compound being EDS microanalysis, by assessing atomic Ca/P ratio. value ratio can be influenced...
The demand of calcium phosphate bioceramics for biomedical applications is constantly increasing. Efficient and cost-effective production can be achieved using naturally derived materials. In this work, powders, obtained from dolomitic marble Mytilus galloprovincialis seashells by a previously reported improved Rathje method were used to fabricate microporous pellets through cold isostatic pressing followed sintering at 1200 °C. interaction the developed materials with MC3T3-E1...
Calcium carbonate from marble and seashells is an eco-friendly, sustainable, largely available bioresource for producing natural bone-like calcium phosphates (CaPs). Based on three main objectives, this research targeted the: (i) adaptation of indirect synthesis route by modulating the amount phosphorus used in chemical reaction, (ii) comprehensive structural, morphological, surface characterization, (iii) biocompatibility assessment synthesized powdered samples. The morphological...
The intersection of the bone tissue reconstruction and additive manufacturing fields promoted advancement to a prerequisite new feedstock resource for high-performance bone-like-scaffolds manufacturing. In this paper, proposed strategy was directed toward use bovine-bone-derived hydroxyapatite (HA) surface properties enhancement mechanical features reinforcement poly(lactic acid) matrix composite filaments extrusion. involvement completely naturally derived materials in technological process...
Additive manufacturing or 3D printing technologies might advance the fabrication sector of personalised biomaterials with high-tech precision. The selection optimal precursor materials is considered first key-step for development new printable filaments destined products diverse orthopaedic/dental applications. route proposed in this study targeted two categories materials: prime materials, polymeric matrix (acrylonitrile butadiene styrene (ABS), polylactic acid (PLA)); and reinforcement...
The proposed strategy for the extrusion of printable composite filaments follows favourable association biogenic hydroxyapatite (HA) and graphene nanoplatelets (GNP) as reinforcement materials a poly(lactic acid) (PLA) matrix. HA particles were chosen in <40 μm range, while GNP selected micrometric range. During melt–mixing incorporation into PLA matrix, both ratios simultaneously modulated first time at different increments. Cylindrical pellets/test samples obtained only mechanical...
Bone tissue engineering is constantly in need of new material development with improved biocompatibility or mechanical features closer to those natural bone. Other important factors are the sustainability, cost, and origin precursors involved technological process. This study focused on two widely used polymers engineering, namely polylactic acid (PLA) thermoplastic polyurethane (TPU), as well bovine-bone-derived hydroxyapatite (HA) for manufacturing core-shell structures. In order embed...
The bone remodeling field has shifted focus towards the delineation of products with two main critical attributes: internal architectures capable to promote fast cell colonization and good mechanical performance. In this paper, Luffa-fibers graphene nanoplatelets were proposed as porogen template reinforcing agent, respectively, in view framing 3D by a one-stage polymer-free process. ceramic matrix was prepared through reproducible technology, developed for conversion marble resources into...
A successful bone-graft-controlled healing entails the development of novel products with tunable compositional and architectural features mechanical performances is, thereby, able to accommodate fast bone in-growth remodeling. To this effect, graphene nanoplatelets Luffa-fibers were chosen as reinforcement phase sacrificial template, respectively, incorporated into a hydroxyapatite brushite matrix derived by marble conversion help reproducible technology. The bio-products, framed...
Hydroxyapatite (HA) is one of the most common ceramic materials used for bone substitutions or reconstructions [1]. HA synthesis from natural sources convenient relative to synthetic preparation while ensuring a similarity with viable tissue in terms chemical composition and some other properties. One important markers hydroxyapatite identification differentiation calcium phosphates Ca/P ratio [2]. In order perform proper identification, this should be evaluated high accuracy, which involves...
The surface physico-chemistry of metallic implants governs their successful long-term functionality for orthopedic and dentistry applications. Here, we investigated the feasibility harmoniously combining two star materials currently employed in bone treatment/restoration, namely, calcium-phosphate-based bioceramics (in form coatings that have capacity to enhance osseointegration) titanium alloys (used as bulk implant due mechanical performance lack systemic toxicity). For first time,...
The paper proposes the use of a nondestructive electromagnetic (NDE) method for evaluation zirconia coating on AISI 316L, based an (EM) sensor with metamaterial lens.Metamaterials (MM), namely conical Swiss roll (CSR), operated in radiofrequency range can serve as EM flux concentrators.EM lens composing sensors are designed basis Fourier optic principles and allows enhancement spatial resolution order to evaluate quality surface /adhesion coating-support.Complementary methods such scanning...
Processing calcium and phosphor-rich natural resources, such as marble seashells, bovine fish bones, envelops an environmentally friendly eco-sustainable promising alternative for developing biomimetic products various orthopaedic applications.In this regard, convenient, efficient, facile completely reproducible technologies were involved in the fabrication process of biogenic phosphates-based through conversion proposed resources.The aim research was to comparatively evaluate...