A5031584508- Smoking Behavior and Cessation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Air Quality and Health Impacts
- Sexuality, Behavior, and Technology
- HIV/AIDS Research and Interventions
- Behavioral Health and Interventions
- Nicotinic Acetylcholine Receptors Study
- HIV/AIDS drug development and treatment
- Pediatric health and respiratory diseases
- Pharmaceutical Economics and Policy
- Autoimmune Bullous Skin Diseases
- Advanced Drug Delivery Systems
- Celiac Disease Research and Management
- HIV Research and Treatment
- SARS-CoV-2 and COVID-19 Research
- Advancements in Transdermal Drug Delivery
- Public Health and Nutrition
- Nanoparticle-Based Drug Delivery
- Metabolism, Diabetes, and Cancer
- Antibiotic Use and Resistance
- COVID-19 Clinical Research Studies
- Obesity, Physical Activity, Diet
- Agriculture, Plant Science, Crop Management
- Lymphatic Disorders and Treatments
- Psoriasis: Treatment and Pathogenesis
Ospedale Garibaldi
2017-2023
Azienda di Rilievo Nazionale ed Alta Specializzazione
2023
University of Catania
2004
Given that many patients with chronic obstructive pulmonary disease (COPD) smoke despite their symptoms, it is important to understand the long-term health impact of cigarette substitution heated tobacco products (HTPs). We monitored parameters for 3 years in COPD who substantially attenuated or ceased consumption after switching HTPs. Changes daily smoking, annualized exacerbations, lung function indices, patient-reported outcomes (CAT scores) and 6-minute walk distance (6MWD) from baseline...
People who smoke and face challenges trying to quit or wish continue may benefit by switching from traditional cigarettes noncombustible nicotine delivery alternatives, such as heated tobacco products (HTPs) electronic (ECs). HTPs ECs are being increasingly used smoking, but there limited data about their effectiveness.
Background and Aims: The long-term health effects of the use electronic cigarettes (ECs) in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. We present findings from a 5-year prospective assessment respiratory parameters cohort COPD who substantially reduced conventional smoking or achieved abstinence by switching to ECs. Methods: Patients were evaluated prospectively for their measurements exacerbations, spirometric indices, quality life using tool (CAT),...
Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping has not been studied rigorous research required to advance best practice outcomes people who use electronic cigarettes (EC) want quit. objective evaluate the (1 mg BID, administered 12 weeks, with follow-up week 24) combined counseling in exclusive daily EC users intending quit vaping. Design: Double-blind, randomized, parallel-group, placebo-controlled trial. study took place at a University-run...
Summary Semaglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist, approved for the treatment of type 2 diabetes mellitus (T2DM). GLP-1 analogs exert several biological activities connected not only with an insulinotropic effect but also immunoregulation and reduction inflammation. A 73-year-old male patient class III obesity was referred to us T2DM, which controlled metformin therapy. He had suffered from plaque psoriasis some years treated topical therapy adalimumab, without...
A Eudragit RL100 polymer nanoparticle system loaded with cloricromene was prepared and characterized on the basis of physicochemical properties, stability drug release features. To investigate ocular bioavailability after inclusion in matrix, new topically administered rabbit eye compared an aqueous solution same drug. The showed interesting size distribution surface charge values, suitable for ophthalmic application. results indicated that dispersion within nanoparticles increased its...
The use of immune suppressive drugs combined with the natural suppression caused by SARS-CoV-2 can lead to a surge secondary bacterial and fungal infections. aim this study was estimate incidence superinfections in hospitalized subjects COVID-19. We carried out an observational retrospective single center cohort study. enrolled patients admitted at "Garibaldi" hospital for ≥72 h, confirmed diagnosis All were routinely investigated bacterial, viral, pathogens. A total 589 adults COVID-19...
Despite the introduction of tobacco control measures, smoking remains highly prevalent in most EU countries. In Italy, one four adults were still regular smokers 2017. Increasing use combustion-free delivering nicotine technologies for cigarette substitution may accelerate current downward trends prevalence. Whether Heated Tobacco Products (HTPs) are more effective substitutes that potentially facilitate adoption and full conversion compared to e-cigarettes (ECs) is not known.We have...
ABSTRACT Background Given that many patients with chronic obstructive pulmonary disease (COPD) smoke despite their symptoms, it is important to understand the long term health impact of cigarette substitution heated tobacco products (HTPs). We monitored parameters for 3-years in COPD who substantially attenuated or ceased consumption after switching HTPs. Methods Changes daily smoking, annualized exacerbations, lung function indices, reported outcomes (CAT scores) and 6-minute walk distance...
Background A one-year cost analysis was conducted to estimate the impact from perspective of Italian National Health Service (NHS) nevirapine or etravirine rilpivirine plus raltegravir administration as maintenance antiretroviral therapy in virologically suppressed HIV-1 infected patients. Methods Patient data were retrieved electronic medical record system use (year 2016) a reference HIV centre South Italy. The considered patients with long-term (more than 1 year) virological suppression (HIV-1 RNA
Background A one-year cost analysis was conducted to estimate the impact from perspective of Italian National Health Service (NHS) nevirapine or etravirine rilpivirine plus raltegravir administration as maintenance antiretroviral therapy in virologically suppressed HIV-1 infected patients. Methods Patient data were retrieved electronic medical record system use (year 2016) a reference HIV centre South Italy. The considered patients with long-term (more than 1 year) virological suppression (HIV-1 RNA
<sec> <title>BACKGROUND</title> People who smoke and face challenges trying to quit or wish continue may benefit by switching from traditional cigarettes noncombustible nicotine delivery alternatives, such as heated tobacco products (HTPs) electronic (ECs). HTPs ECs are being increasingly used smoking, but there limited data about their effectiveness. </sec> <title>OBJECTIVE</title> We conducted the first randomized controlled trial comparing rates between among people do not intend quit....
ABSTRACT Background Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping has not been studied rigorous research required to advance best practice outcomes e-cigarettes users who want quit. Methods Eligible patients were randomized either (1 mg, administered twice daily 12 weeks) or placebo treatment (administered daily, combined with counseling. trial consisted a 12-week phase followed by follow-up, nontreatment phase. primary endpoint the study was...