A5019781356- Gyrotron and Vacuum Electronics Research
- Pulsed Power Technology Applications
- Terahertz technology and applications
- Microwave Engineering and Waveguides
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Particle accelerators and beam dynamics
- PI3K/AKT/mTOR signaling in cancer
- Cardiovascular Effects of Exercise
- Advanced Memory and Neural Computing
- 2D Materials and Applications
- Inflammatory mediators and NSAID effects
- Potassium and Related Disorders
- Solid State Laser Technologies
- Chalcogenide Semiconductor Thin Films
- Cardiac tumors and thrombi
- Heart Failure Treatment and Management
- Neural Networks and Reservoir Computing
- S100 Proteins and Annexins
- Inflammasome and immune disorders
- Advanced Fiber Laser Technologies
- Cancer Cells and Metastasis
- Biomarkers in Disease Mechanisms
- MXene and MAX Phase Materials
- Laser-Matter Interactions and Applications
Second Xiangya Hospital of Central South University
2024-2025
Central South University
2024-2025
University of Sheffield
2022-2024
Xi’an Jiaotong-Liverpool University
2023
Shuguang Hospital
2021
Shanghai University of Traditional Chinese Medicine
2021
East China Normal University
2019
Xuzhou Medical College
2018
Second People’s Hospital of Huai’an
2018
University of London
2009-2010
Radiofrequency ablation (RFA) has been a central therapeutic strategy for ventricular tachycardia (VT). However, concerns about its long-term effectiveness and complications have arisen. Pulse field (PFA), characterized by nonthermal, highly tissue-selective technique, emerged as promising alternative. This comprehensive review delves into the potential advantages opportunities presented PFA in realm of VT, drawing insights from both animal experimentation clinical case studies. shows...
The delayed titration of guideline-directed drug therapy (GDMT) is a complex event influenced by multiple factors that often result in poor prognosis for patients with heart failure (HF). Individualized adjustments GDMT may be necessary based on patient characteristics, and every clinician responsible promptly initiating titrating it appropriately within the patient's tolerance range. This review examines current challenges implementation scrutinizes considerations distinct subsets HF...
Interleukin-1B (IL-1B) is a potent pro-inflammatory cytokine that plays multiple, pivotal roles, in the complex interplay between breast cancer cells and bone microenvironment. IL-1B involved growth of primary tumours, regulation inflammation within tumour microenvironment, promotion epithelial to mesenchymal transition (EMT), migration invasion. Moreover, when arrive microenvironment there an upregulation which promotes creation conducive niche for metastatic as well stimulating initiation...
Malnutrition presents a significant challenge in managing patients with atrial fibrillation (AF) and heart failure preserved ejection fraction (HFpEF), yet its impact on AF recurrence after catheter ablation this population remains unclear. We conducted retrospective analysis of 204 paroxysmal non-valvular HFpEF who underwent radiofrequency or cryoballoon ablation. Risk malnutrition as assessed using three screening tools: the Controlling Nutritional Status (CONUT) score, Prognostic Index...
Background: The role of fractional flow reserve (FFR) in intermediate lesions has been widely used and recommended by guidelines. However, the long-term outcomes patient with an stenosis received FFR have not yet investigated comprehensively. Methods: We retrospectively included 558 patients underwent both coronary artery angiography (CAG) FFR. Multivariate logistic regression analysis was employed to identify independent predictors major adverse cardiovascular cerebrovascular events...
We have synthesized high quality and large area MoS2 films on flexible fluorophlogopite substrates using the pulsed-laser deposition (PLD) technique. Annealing in a sufficient sulfur atmosphere was adopted to eliminate oxide molybdenum vacancies introduced during growth vacuum chamber. X-ray photoelectron spectroscopy results demonstrate advantages benefitted from annealing process. The S/Mo ratio of annealed film 1.98:1, which much closer theoretical value. Raman spectroscopy,...
Increasing uric acid (UA) could induce renal tubular epithelial cell (NRK‑52E) injury. However, the specific mechanism by which UA induces injury remains unknown. It was hypothesized that through reactive oxygen species (ROS) and Never in mitosis gene A (NIMA)‑related kinase 7 (NEK7)/NLR family pyrin domain containing 3 (NLRP3) signaling pathway. TUNEL assay flow cytometry were applied to measure apoptosis, results of present study showed treatment induced apoptosis NRK‑52E cells a...
Breast cancer bone metastasis is currently incurable. Evidence suggests that inhibiting IL-1 signalling with the IL1R antagonist, Anakinra, or IL1β antibody, Canakinumab, prevents and almost eliminates breast growth in bone. However, these drugs increase primary tumour growth. We, therefore, investigated whether targeting other members of pathway (Caspase-1, IRAK1) could reduce metastases without increasing outside Inhibition via MLX01 (IL1β secretion inhibitor), VRT043198/VX765 (Caspase-1...
The mode locking of a cw Nd:YAG laser by translation one the cavity mirrors is reported. mode-locking effect greatly enhanced when an intracavity nonlinear KTP crystal used. Stable pulse trains with 60-ps average width are obtained. Theoretical analysis shows that combined linear phase shift imposed moving mirror and in Kerr medium gives rise to saturable-absorber-like behavior homogeneously broadened laser. theory agrees well experimental results as obtained Ti:sapphire
Based on previous experimental investigations pseudospark (PS) discharges, a small-scaled PS electron beam source was conceived to drive 200GHz microklystron. Recent e-beam experiments producing of 1mm in diameter and klystron interaction simulations will be presented. The microklystron fabricated using micro-electro-mechanical systems (MEMS) construction techniques.
Summary form only given: Demands in plasma diagnostics, radiotherapy, medical research and advanced communications have recent years resulted the development of new radiation sources terahertz region (0.1 to 10 THz). A klystron is one attractive choice for generation THz due its operation mechanism, efficiency robustness because structure amenable being scaled down size achieve higher frequency operation. Due decrease as increased, there a need electron beam current density increase order...
A multicavity microklystron operating in the terahertz region has been designed and simulated. This will be driven by an electron beam sourced a down-scaled pseudospark discharge.
Based on previous experimental investigations pseudospark (PS) discharges, a small-scaled PS electron beam source was conceived to drive 200GHz microklystron. Recent e-beam experiments producing of 1mm in diameter and klystron interaction simulations will be presented. The microklystron fabricated using micro-electro-mechanical systems (MEMS) construction techniques.
Summary form only given. In recent years much interest has been shown in radiation sources the terahertz region (0.1 to 10THz) because of demands plasma diagnostics, radiotherapy, medical research and advanced communications. The Klystron is an ideal choice for THz generation due its operation mechanism, efficiency robustness as well fact that it may be scaled size order achieve higher frequency operation. Due decrease increased, there a need electron beam current density increase reasonable...
Summary form only given. Terahertz radiation, which ranges from 0.1 THz to 10 THz, has received substantial interests in recent years. The conventional vacuum electronics technology the potential supply high enough powers underpin many exciting and emerging applications. Klystrons have been designed generate radiation. This device requires a very small sized RF circuit thin electron beam with reasonable energy. pseudospark discharge can provide suitable current density diameter (< 1 mm)...