Sina Dadmand

ORCID: 0000-0003-1109-0729
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About
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Research Areas
  • Crystallization and Solubility Studies
  • Computational Drug Discovery Methods
  • Drug Solubulity and Delivery Systems
  • Analytical Chemistry and Chromatography
  • Bioinformatics and Genomic Networks
  • COVID-19 Clinical Research Studies
  • Gene Regulatory Network Analysis
  • Chemical and Physical Properties in Aqueous Solutions
  • Phase Equilibria and Thermodynamics
  • Microbial Metabolic Engineering and Bioproduction
  • Biomedical Text Mining and Ontologies
  • SARS-CoV-2 and COVID-19 Research

Koç University
2022-2023

Tabriz University of Medical Sciences
2018-2020

Coronavirus disease 2019 (COVID-19) continues to threaten public health globally. Severe acute respiratory coronavirus type 2 (SARS-CoV-2) infection-dependent alterations in the host cell signaling network may unveil potential target proteins and pathways for therapeutic strategies. In this study, we aim define early severity biomarkers monitor altered course of SARS-CoV-2 infection.We systematically analyzed plasma proteomes COVID-19 patients from Turkey by using mass spectrometry....

10.1002/prca.202200070 article EN PROTEOMICS - CLINICAL APPLICATIONS 2022-10-11

The intricate nature of biological processes is orchestrated by molecular interactions. complexity these interactions stems from the sheer number components involved and their relationships. To overcome this complexity, network medicine adopts a holistic, integrative approach at multiple levels. human interactome involves over 100,000 molecules, including proteins, RNAs, metabolites, all interconnected connections. One challenge in understanding associating specific parts with phenomena such...

10.1109/tmbmc.2023.3308689 article EN IEEE Transactions on Molecular Biological and Multi-Scale Communications 2023-08-25

The molar solubility of celecoxib (CXB) was measured in the binary mixtures 1-propanol + water at temperatures ranging from 293.2 to 313.2 K. obtained data are mathematically represented by employing five cosolvency models (i.e. van't Hoff equation, Yalkowsky–Roseman model, Jouyban–Acree Jouyban–Acree–van't model and modified Wilson model), mean relative deviations (MRD%) calculated for back-calculated were 2.5%, 68.7%, 12.7%, 12.8% 20.5%, respectively, each investigated model. apparent...

10.1080/00319104.2018.1553241 article EN Physics and Chemistry of Liquids 2018-12-10

Abstract In this study, with the use of information theory, we have proposed and proved a mathematical theorem by which argue reason for existence human diseases. To introduce our theoretical frame reference, first, put forward modification Shannon’s entropy, computed all available proteomes, as tool to compare systems complexity distinguish between several levels biological organizations. We establish new approach differentiate taxa corroborate findings through latest tree life....

10.1101/2020.08.03.233767 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-08-04
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