- Crystallization and Solubility Studies
- Computational Drug Discovery Methods
- Drug Solubulity and Delivery Systems
- Analytical Chemistry and Chromatography
- Bioinformatics and Genomic Networks
- COVID-19 Clinical Research Studies
- Gene Regulatory Network Analysis
- Chemical and Physical Properties in Aqueous Solutions
- Phase Equilibria and Thermodynamics
- Microbial Metabolic Engineering and Bioproduction
- Biomedical Text Mining and Ontologies
- SARS-CoV-2 and COVID-19 Research
Koç University
2022-2023
Tabriz University of Medical Sciences
2018-2020
Coronavirus disease 2019 (COVID-19) continues to threaten public health globally. Severe acute respiratory coronavirus type 2 (SARS-CoV-2) infection-dependent alterations in the host cell signaling network may unveil potential target proteins and pathways for therapeutic strategies. In this study, we aim define early severity biomarkers monitor altered course of SARS-CoV-2 infection.We systematically analyzed plasma proteomes COVID-19 patients from Turkey by using mass spectrometry....
The intricate nature of biological processes is orchestrated by molecular interactions. complexity these interactions stems from the sheer number components involved and their relationships. To overcome this complexity, network medicine adopts a holistic, integrative approach at multiple levels. human interactome involves over 100,000 molecules, including proteins, RNAs, metabolites, all interconnected connections. One challenge in understanding associating specific parts with phenomena such...
The molar solubility of celecoxib (CXB) was measured in the binary mixtures 1-propanol + water at temperatures ranging from 293.2 to 313.2 K. obtained data are mathematically represented by employing five cosolvency models (i.e. van't Hoff equation, Yalkowsky–Roseman model, Jouyban–Acree Jouyban–Acree–van't model and modified Wilson model), mean relative deviations (MRD%) calculated for back-calculated were 2.5%, 68.7%, 12.7%, 12.8% 20.5%, respectively, each investigated model. apparent...
Abstract In this study, with the use of information theory, we have proposed and proved a mathematical theorem by which argue reason for existence human diseases. To introduce our theoretical frame reference, first, put forward modification Shannon’s entropy, computed all available proteomes, as tool to compare systems complexity distinguish between several levels biological organizations. We establish new approach differentiate taxa corroborate findings through latest tree life....