A5053856033- Clinical Nutrition and Gastroenterology
- Vagus Nerve Stimulation Research
- Poisoning and overdose treatments
- Liver Diseases and Immunity
- Nicotinic Acetylcholine Receptors Study
- Infant Nutrition and Health
- Liver Disease Diagnosis and Treatment
- Muscle and Compartmental Disorders
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Clostridium difficile and Clostridium perfringens research
- Dialysis and Renal Disease Management
- Advanced MRI Techniques and Applications
- Receptor Mechanisms and Signaling
- Child Nutrition and Water Access
- Electrolyte and hormonal disorders
CIC biomaGUNE
2013-2016
Macrophages play an important role in rhabdomyolysis-acute kidney injury (AKI), although the molecular mechanisms involved macrophage differentiation are poorly understood. We analyzed expression and regulation of CD163, a membrane receptor mainly expressed by anti-inflammatory M2 macrophages, rhabdomyolysis-AKI developed targeted probes for its specific detection vivo MRI. Intramuscular injection glycerol mice promoted early inflammatory response, with elevated proportion M1 partial towards...
PET imaging of nicotinic acetylcholine receptors (nAChRs) could become an effective tool for the diagnosis and therapy evaluation neurologic diseases. Despite this, role nAChRs α4β2 after brain diseases such as cerebral ischemia its involvement in inflammatory reaction is still largely unknown. To investigate we performed parallel vivo magnetic resonance (MRI) positron emission tomography (PET) with 2[(18)F]-fluoro-A85380 [(11)C]PK11195 at 1, 3, 7, 14, 21, 28 d middle artery occlusion (MCAO)...
The use of selective serotonin reuptake inhibitors has shown functional improvement after stroke. Despite this, the role serotoninergic neurotransmission cerebral ischemia evolution and its involvement in recovery processes are still largely unknown. For this purpose, we performed parallel vivo magnetic resonance imaging positron emission tomography (PET) with [ 11 C]DASB 18 F]altanserin at 1, 3, 7, 14, 21, 28 days middle artery occlusion (MCAO) rats. In ischemic territory, PET showed a...