A5007186704- Cystic Fibrosis Research Advances
- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Congenital Ear and Nasal Anomalies
- Advanced Causal Inference Techniques
- Healthcare Policy and Management
- Traffic Prediction and Management Techniques
- Statistical Methods and Bayesian Inference
- Transplantation: Methods and Outcomes
- Geriatric Care and Nursing Homes
- Tracheal and airway disorders
- Statistical Methods in Clinical Trials
- Traffic and Road Safety
- Stroke Rehabilitation and Recovery
- Neuroethics, Human Enhancement, Biomedical Innovations
- Infrastructure Maintenance and Monitoring
- Educational Strategies and Epistemologies
- Influenza Virus Research Studies
- Balance, Gait, and Falls Prevention
- Machine Learning and Algorithms
- Vehicle emissions and performance
- Innovations in Medical Education
- Vaccine Coverage and Hesitancy
- Dysphagia Assessment and Management
- COVID-19 and Mental Health
Kaiser Permanente Washington Health Research Institute
2023-2025
Kaiser Permanente Capitol Hill Medical Center
2023
University of Wyoming
2018-2022
Google (United States)
2022
Case Western Reserve University
2012-2018
University of Akron
2012
The aim of this study was to assess differences in utilization outcomes among patients with social needs as part a pilot health integration program 2 clinics an integrated system the Pacific Northwest. Patients who reported between October 2022 and January 2023 were randomized receive support from either local, clinic-based community resource specialists or centralized Connections Call Center. authors used administrative claims data for 534 participants compare following arms over 9 months...
Importance High-risk medications that contribute to adverse health outcomes are frequently prescribed older adults. Deprescribing interventions reduce their use, but studies often not designed examine effects on patient-relevant outcomes. Objective To test the effect of a system–embedded deprescribing intervention targeting adults and primary care clinicians for reducing use central nervous system–active drugs preventing medically treated falls. Design, Setting, Participants In this cluster...
Previous reports of lung function in cystic fibrosis (CF) patients with liver disease have shown worse, similar, or even better forced expiratory volume 1 second (FEV1), compared to CF without disease. Varying definitions likely contribute these inconsistent relationships reported between and We retrospectively evaluated spirometric data 179 subjects (62% male; 58% Phe508del homozygous) severe (CFLD; defined by presence portal hypertension due cirrhosis). FEV1 values were referenced both a...
Numerous methods for joint analysis of longitudinal measures a continuous outcome y and time to event T have recently been developed either focus on the data while correcting nonignorable dropout, predict survival using , or examine relationship between . The motivating problem our work is in modeling serial measurements pulmonary function (FEV1% predicted) cystic fibrosis (CF) patients registry data. Within CF data, an additional complexity that not all followed from birth; therefore, some...
Many longitudinal studies observe time to occurrence of a clinical event such as death, while also collecting serial measurements one or more biomarkers that are predictive the event, surrogate outcomes interest. Joint modeling can be used examine relationship between biomarker and way adjusting analyses for non-ignorable dropout. In settings registry studies, an additional complexity is caused when follow-up subjects delayed, referred left-truncation in survival analysis setting. If not...
Purpose: Limited quantitative data exist regarding growth of the velopharynx within first 2 years life. The purpose this study was to (a) quantify changes in velopharyngeal structures due during life, (b) examine impact sex and race age range, (c) provide normative measures for comparison individuals with cleft palate. Method/Description: A retrospective chart review completed all patients up 24 months that underwent magnetic resonance imaging head medical necessity past 18 using a...
Objective To quantify differences in levator veli palatini (LVP) muscle dimensions based on age, sex, and race determine the typical range of asymmetry between left right sides LVP under age 2 Design Retrospective cohort study Setting Children's tertiary care hospital Participants A retrospective chart review non-cleft patients who received a volumetric FLAIR MRI sequence within past 18 months identified 216 patient scans. Exclusion criteria 200 scans for analysis. Measurements were obtained...
Purpose: The purpose of the present study is to (a) provide quantitative data on growth levator veli palatini (LVP), velopharyngeal (VP), and craniofacial dimensions in children under 12 months while controlling for corrected age sex (b) compare variability within groups. Method: Magnetic resonance imaging scans 75 infants between 0 were measured divided into four These obtained as part a larger retrospective study. Following exclusion criteria, analyzed, dependent variables obtained....
Background The duration of time a person with cystic fibrosis (pwCF) spends on the lung transplant waitlist is dependent and post-transplant survival probabilities can extend up to 2 years. Understanding characteristics involved prognoses may help guide decision making by patient, referring CF Center team. Methods This study seeks identify clinical predictors individuals using 29,847 subjects from 2003–2014 entered in Cystic Fibrosis Foundation Patient Registry (CFFPR). Results Predictors...
During a clinical trial, balancing statistical and ethical considerations are important. Response-adaptive randomization methods use the information from past patients to increase probability of next patient receiving better treatment while avoiding concern selection bias. We compared three response-adaptive urn designs, Randomized Play-the-Winner, Modified Birth-and-Death Urn with Immigration, traditional equal allocation design respect power treatment. Because these designs have been...
Background: COVID-19 vaccination rates among long-term care center (LTCC) workers are the lowest of all frontline health workers. Current efforts to increase vaccine uptake generally focus on strategies that have proven effective for increasing influenza including educational and communication strategies. Experimental evidence is lacking comparative advantage improve acceptance uptake, especially in context COVID-19. Despite lack evidence, education recommended decrease hesitancy (VH), using...
ABSTRACT Background The duration of time a person with cystic fibrosis (pwCF) spends on the lung transplant waitlist is dependent and post-transplant survival probabilities can extend up to 2 years. Understanding characteristics involved prognoses may help guide decision making by patient, referring CF Center team. Methods This study seeks identify clinical predictors individuals using 29,847 subjects from 2003-2014 entered in Cystic Fibrosis Foundation Patient Registry (CFFPR). Results...
Abstract The Inventory for Client and Agency Planning (ICAP) the Supports Intensity Scale (SIS) have been used to determine Medicaid eligibility individuals with disabilities but are designed capture different information. This project explored how these surveys relate services received each other. ICAP SIS were conducted on 125 [Blinded] adults intellectual developmental eligible a Waiver. Results suggest that both measures strongly associated could be predict services. However, this study...