- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Adipose Tissue and Metabolism
- Angiogenesis and VEGF in Cancer
- Biochemical effects in animals
- Cardiac Ischemia and Reperfusion
- Peroxisome Proliferator-Activated Receptors
- Pharmacological Effects of Natural Compounds
- Cancer, Lipids, and Metabolism
- Neuropeptides and Animal Physiology
- Adipokines, Inflammation, and Metabolic Diseases
- Regulation of Appetite and Obesity
- Curcumin's Biomedical Applications
- MicroRNA in disease regulation
- Phytoestrogen effects and research
- Pregnancy and preeclampsia studies
- Gynecological conditions and treatments
- Cancer Research and Treatments
- Anatomy and Medical Technology
- Immune Response and Inflammation
- Multiple Sclerosis Research Studies
- Nitric Oxide and Endothelin Effects
- Heart Rate Variability and Autonomic Control
- Pharmacological Effects of Medicinal Plants
- Ziziphus Jujuba Studies and Applications
Isfahan University of Medical Sciences
2014-2024
Islamic Azad University Medical Branch of Tehran
2024
Luhansk State Medical University
2021
Mashhad University of Medical Sciences
2018
University of Isfahan
2012
AntiCancer (United States)
2000
Several factors lead to memory loss, the most important of which is brain aging that caused mostly by neuroinflammation and oxidative stress. The need finding preventive treatments impairment in elderly encouraged authors assess effect Acorus calamus on anxiety, antioxidant indices rat models.Different fractions A. were prepared. subject rats grouped 11 groups 10 each. In nine treated groups, extract gavage began 1 week before intraperitoneal (i.p.) injection lipopolysaccharide (LPS)...
Background : Thyroid cancer is a common endocrine malignancy whose incidence has increased in recent years. Several internal and external risk factors are involved the development of this cancer, such as infectious agents. Evidence supporting role viral infection an etiology for invasiveness thyroid increasing. The aim study was to determine presence Epstein–Barr virus (EBV) association between gene products tumor development. Methods Fifty‐seven specimens were collected from same number...
Alzheimer's disease (AD) is a prevalent disorder with severe learning and memory defects. Because it has been demonstrated that erythropoietin (EPO) positive effects on the central nervous system, aim of this study was to evaluate effect EPO neuronal proliferation in dentate gyrus hippocampal formation well-defined model for AD.A rat sporadic dementia type established by bilateral intracerebroventricular injection streptozotocin (ICV-STZ). Impairment confirmed 2 weeks after ICV-STZ passive...
Abstract Breast cancer (BC) is an important cause of female cancer‐related death. It has recently been demonstrated that metabolic disorders including lipid metabolism are a hallmark cells. Lipin‐1 enzyme displays phosphatidate phosphatase activity and regulates the rate‐limiting step in pathway triglycerides phospholipids synthesis. The objective this study was to evaluate lipin‐1 expression, its prognostic significance, correlation with p53 tumor suppressor patients BC. In study, 55 pairs...
Breast cancer (BC) is one of the major causes female cancer-related death. It has recently been demonstrated that metabolic reprogramming including alteration in lipid metabolism indicated various types cancer. The enzymes acyl-coenzyme A synthetase long-chain family (ACSLs) are responsible for converting fatty acids to their corresponding esters which essential some pathways. ACSL4 isoforms ACSLs and a marked preference arachidonic eicosapentaenoic acids. objective this study was evaluate...
Alzheimer's disease is associated to impairments of learning and memory. Because studies demonstrated that erythropoietin has positive effects on central nervous system, the aim this study was evaluate effect spatial memory in a well defined model for disease. Rat created by injecting streptozotocin lateral ventricles brain. Two weeks later, rats were assessed through passive avoidance test confirm induction Alzheimer's. After that, they received (5000IU/kg) every other day, two then 5-day...
In this study, we investigated the effects of genistein, daidzein, and soy protein on paraoxonase arylesterase activity, malondialdehyde (MDA) levels, lipid profiles arthritic rats in vivo results were compared with that dexamethasone. Seventy-two female Sprague-Dawley divided into six groups: healthy control, animals collagen-induced arthritis (CIA), CIA-soy (7 g/kg)-treated rats, CIA-genistein (20 mg/kg)-treated animals, CIA-daidzein CIA-dexamethasone (1 rats. Rheumatoid was induced using...
Abstract Background : Diabetes mellitus arises from a deficient production and action of insulin. Ziziphus vulgaris L. (jujube) is medicinal plant that known to have anti-diabetic actions. The aim the present study was investigate protective effects jujube fruit powder extract against biochemical imbalances in stereptozotocin (STZ)-induced diabetes. Methods induced rats using intraperitoneal injection STZ at dose 60 mg/kg body weight (bw). Jujube (1 g/kg bw) were administered daily via...
We have already shown the protective effects of soy protein on rheumatoid arthritis in rats. In this study, genistein and daidzein, two isoflavones from prognosis prevention rats been investigated.Rheumatoid was induced female Sprague-Dawley using collagen type II plus adjuvant. Rats were then treated with (7 g/kg), dexamethasone (1 mg/kg), (20 mg/kg genistein), daidzein genistein) casein (in control groups) by daily gavage feedings for 50 days. Scores recorded every day each paw animal....
There is an increase in inflammatory and a reduction anti-inflammatory cytokines multiple sclerosis (MS). Considering the role of thyroid hormones development regulation both neural immune systems, aim this study was to evaluate effects levothyroxine on serum concentrations interleukin-10 (IL-10) interferon gamma (IFN-γ) animal models MS.To induce demyelination male Wistar rats, lysolecithin injected into optic chiasm. Then intraperitoneally (20, 50, 100 μg/kg) for 21 days. Serum levels were...