A5065003561- Carcinogens and Genotoxicity Assessment
- Pesticide Exposure and Toxicity
- Phytochemistry Medicinal Plant Applications
- Healthcare during COVID-19 Pandemic
- Pesticide and Herbicide Environmental Studies
- Evasion and Academic Success Factors
- Health, Nursing, Elderly Care
- Exercise and Physiological Responses
- Youth, Drugs, and Violence
- Business and Management Studies
- Public Health in Brazil
- Occupational and environmental lung diseases
- Systemic Sclerosis and Related Diseases
- IL-33, ST2, and ILC Pathways
- Health, Medicine and Society
- Science and Education Research
- Diabetes Treatment and Management
- Air Quality and Health Impacts
- Immunotherapy and Immune Responses
- Inflammasome and immune disorders
- Protein Structure and Dynamics
- Pancreatic function and diabetes
- Biotechnology and Related Fields
- Palliative and Oncologic Care
- Healthcare Systems and Practices
Universidade Federal de Jataí
2019-2024
Universidade Federal de Goiás
2019-2023
Universidade Estadual de Campinas (UNICAMP)
2013-2020
CHU Dijon Bourgogne
2015
In the health area, amount of research related to religion/religiosity/spirituality has been growing in recent years, however, dimension and publications needs be better explored. This study aimed present a bibliometric analysis documents published on topic spirituality/religion medical field years. There was an active search Scopus database with terms: “health” OR “spirituality” “medicine” “medical practice”, obtaining 98 documents, which 55 articles were between 1988 2021. The presented...
Abstract Pathogenic CD4+ T cells are capable of initiating neuroinflammation in experimental autoimmune encephalomyelitis (EAE). However, the precise effector mechanism these autoaggressive is not entirely elucidated. Here, we demonstrated that pathogenic cells, upon autoantigen stimulation, developed a cytotoxic phenotype at onset EAE. The activity was sufficient to explain initial myelin lesion. Consistently, peripheral blood (PBMCs) and cerebrospinal fluid (CSF) from relapse-remitting...
Parkinson's disease (PD) is a neurodegenerative, chronic, and progressive disease, common in the elderly. The catechol-O-methyltransferase (COMT) monomeric enzyme involved dopamine (DA) degradation, neurotransmitter deficit patients with PD. reference treatment of PD consists levodopa (L-dopa) administration, which precursor DA. inhibition COMT an adjuvant since it keeps DA levels constant. goal this study was to identify drug candidates capable inhibiting for important fragments these...
<h3>Background</h3> Moderate exercise improves the functions of immune system. The results serum immunoglobulins in response to acute physical are conflicting, but general, there is an increase athletes and non-athletes after maximal submaximal exercise. effects on immunoglobulin patients with systemic lupus erythematosus unknown. <h3>Objectives</h3> To determine levels IgG, IgM IgA a single session aerobic <h3>Methods</h3> Thirty-one women SLE (ACR1997 and/or SLICC 2012 criteria),11 active...
It is known that individuals directly exposed to pesticides are more susceptible changes in hematological and biochemical parameters. However, there no studies comparing the effects of direct indirect exposure on such This study aimed verify if indirectly, but still massively due residing or working agricultural areas with intense pesticide application, exhibit alterations. Analyses were conducted 62 a municipality located Midwest region Brazil, half them being rural workers (occupationally)...
O câncer e uma doenca caracterizada por crescimento celular desordenado em decorrencia de mutacoes geneticas fatores ambientais, podendo acometer os mais variados tecidos orgaos, alem se disseminar para distantes do foco inicial atraves da corrente sanguinea vasos linfaticos. mama, classificado acordo com as celulas acometidas intraductal ou intralobular, representa 20% todos tipos existentes no mundo. Seu tratamento abrange varias abordagens terapeuticas, sendo que cada qual possui eficacia...
Exposure to pesticides is an important risk factor for genotoxicity in farmworkers. Once there a possibility that related the autoimmunity process, present study aimed characterize and possible immunological alterations chronic direct exposure complex mixture of pesticides. It employed Interleukin–6 (IL-6), Interferon-gamma (IFN-γ), IL-12 IL-10 as biomarkers cellular immune function. DNA damage was greater exposed group (p < 0.05). Both IL-6 were significantly increased 0.05 0.01,...
The Social Assistance Referral Centers provide notorious assistance to the population in situations of social vulnerability. Considering importance dissemination information about health this public, work aims report implementation and execution extension project ‘Information is Health’ order contribute knowledge university outreach context Popular Education Health units municipality Jataí-Goiás, methodologies employed meetings included: conversation circles, question answer dynamics,...
Abstract In recent years, the use of pesticides has intensified worldwide, and many countries have tended to neglect potential toxic effects associated with indiscriminate these substances. Many diseases, such as Hodgkin’s lymphoma, lung prostate cancer, autoimmune disorders, been linked pesticides. The present study compared DNA damage observed in rural workers from five different areas central Brazilian state Goiás. We attempted identify factors that influence patterns genotoxicity found...
Physical exercise improves physical ability, muscle function, and various clinical symptoms, may enhance the immune response in systemic lupus erythematosus (SLE). The effect of on cytokine levels SLE has been under evaluated. aim this study was to determine IL-6, IL-10, IL17A, TNF-α IFN-α serum patients with active inactive before after acute exercise.
O ensino da Farmacologia reune conteudos extensos e complexos que podem gerar dificuldades duvidas, as quais dificultar o aprendizado pelo aluno. A monitoria, neste contexto, apresenta-se como um apoio extensao das atividades desenvolvidas docente auxilio ao estudo do academico, reafirmando a importância na futura pratica profissional medica. monitoria no curso de medicina tem por objetivo auxiliar formacao profissionais medicos repasse embasamento teorico sobre os diversos medicamentos seus...
Background: Type 2 diabetes mellitus (T2DM) is an independent risk factor for cardiovascular impairment, increasing the rates of atherosclerotic and non-atherosclerotic events. Additionally, adverse kidney events are directly linked with T2DM diseases. In this context, sodium-glucose cotransporter inhibitors (SGLT2i) have demonstrated both cardioprotective renoprotective effects in patients or without T2DM. Therefore, present meta-analysis aims to evaluate outcomes involving SGLT2i as...
O cenário pandêmico causado pelo coronavírus SARS-COV-2, levou instituições do mundo todo a fecharem as portas e encerrarem atividades presenciais, com o intuito de diminuir disseminação novo assim conter os avanços da pandemia. Brasil, sendo um dos países mais afetados por essa nova emergência global, seguiu linha adotada outros suspendeu presenciais das ensino tempo indeterminado. Para tentar minimizar prejuízo suspensão calendários dar continuidade às ensino, foi implantada uma modalidade...
A leucemia mieloide cronica, neoplasia mieloproliferativa maligna, caracteriza-se por alteracoes no desenvolvimento de linhagens granulares. As terapias disponiveis apresentam limitacoes, fazendo-se necessaria a busca tratamentos alternativos. Eremanthus erythropappus (EE), destaca-se pela producao do oleo essencial (OE) rico em alfa-bisabolol (?-B), sustância com propriedades antitumorais. Este trabalho investigou acao citotoxica OE EE sobre celulas K-562 e fibroblastos 3T3, ?-B isolado os...