A5101422780- Cancer-related molecular mechanisms research
- Mycobacterium research and diagnosis
- MicroRNA in disease regulation
- Cancer-related gene regulation
- RNA modifications and cancer
Xingtai People's Hospital
2019
Hebei Medical University
2019
Purpose: Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) has been deemed an oncogene in many human cancers.However, the underlying mechanism of NEAT1 nasopharyngeal carcinoma (NPC) progression remains largely unclear.Materials and Methods: Quantitative real-time PCR assay was performed to assess expression miR-34a-5p NPC tissues cells.Western blot analysis used observe cell epithelial mesenchymal transition (EMT) activation Wnt/β-catenin signaling 5-8F cells.MiRNA...
Nasopharyngeal carcinoma (NPC) is one common head and neck malignancy with leading cause of cancer-related death. Long noncoding RNAs (lncRNAs) have been reported to play essential roles in progression, prognosis treatment NPC. However, the exact role lncRNA zinc finger antisense 1 (ZFAS1) NPC progression its potential mechanism remain largely unknown.The expressions ZFAS1 microRNA-135a (miR-135a) were measured tissues or cells by quantitative real-time polymerase chain reaction (qRT-PCR)....