A5103017569- Ubiquitin and proteasome pathways
- Histone Deacetylase Inhibitors Research
- Hippo pathway signaling and YAP/TAZ
- Lipid metabolism and biosynthesis
- Indoor Air Quality and Microbial Exposure
- Metabolism, Diabetes, and Cancer
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Mycotoxins in Agriculture and Food
- Endoplasmic Reticulum Stress and Disease
- Carcinogens and Genotoxicity Assessment
First Affiliated Hospital of Zhengzhou University
2019-2024
Metformin, a first-line drug for type 2 diabetes, could induce apoptosis in cancer cells. However, the concentration of glucose affects effect metformin, especially low culture medium can enhance cytotoxicity metformin on Since mitochondria and endoplasmic reticulum is vital maintaining cell homeostasis, we speculate that metformin-induced may be associated with reticulum. ASK1, as signaling regulating kinase 1, mitochondrial damage. This study was designed to investigate functional...
Deoxynivalenol (DON) is one of the most common mycotoxins distributed in food and feed, which causes severe liver injury humans animals. Cold atmospheric plasma (CAP) has received much attention mycotoxin degradation due to advantages easy operation, high efficiency, low temperature. So far, majority studies have focused on efficiency mechanism CAP DON, while there still little information available hepatotoxicity DON after treatment. Herein, this study aimed investigate effect DON-induced...