A5100436537- Light effects on plants
- Photoreceptor and optogenetics research
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Plant Stress Responses and Tolerance
- Microbial bioremediation and biosurfactants
- Remote Sensing in Agriculture
- Photochromic and Fluorescence Chemistry
- Plant nutrient uptake and metabolism
- bioluminescence and chemiluminescence research
- Insect-Plant Interactions and Control
- Bioenergy crop production and management
- Leaf Properties and Growth Measurement
- Genetic Mapping and Diversity in Plants and Animals
- Plant Gene Expression Analysis
- Insect Pest Control Strategies
- Adsorption and biosorption for pollutant removal
- Microplastics and Plastic Pollution
- Plant responses to water stress
- Animal Disease Management and Epidemiology
- Air Quality and Health Impacts
- Plant biochemistry and biosynthesis
- Postharvest Quality and Shelf Life Management
- Pharmaceutical and Antibiotic Environmental Impacts
Chongqing Medical and Pharmaceutical College
2025
The Ohio State University
2012-2025
Southern University of Science and Technology
2022-2025
Southern Medical University
2025
Nanfang Hospital
2025
China University of Geosciences (Beijing)
2023-2025
Southwest University
2025
Soil and Fertilizer Institute of Hunan Province
2025
China Agricultural University
2022-2024
Shanghai Jiao Tong University
2024
Microplastics (MPs) are environmental pollutants and can be inhaled by humans to threaten health. The lung tissue, responsible for the gas exchange between body environment, is vulnerable MPs exposure. However, from perspective of cellular senescence, effect on cells tissues has not yet been deeply dissected. In this study, we reported that all four typical exhibited significant biological effects in term inducing senescence human derived A549 BEAS-2B vitro. We further found polyvinyl...
Photolyase uses light energy to split UV-induced cyclobutane dimers in damaged DNA, but its molecular mechanism has never been directly revealed. Here, we report the direct mapping of catalytic processes through femtosecond synchronization enzymatic dynamics with repair function. We observed electron transfer from excited flavin cofactor dimer 170 ps and back repaired thymines 560 ps. Both reactions are strongly modulated by active-site solvation achieve maximum efficiency. These results...
We report here our systematic studies of excited-state dynamics two common flavin molecules, FMN and FAD, in five redox states—oxidized form, neutral anionic semiquinones, fully reduced hydroquinones—in solution inert protein environments with femtosecond resolution. Using environments, we were able to stabilize semiquinone radicals thus observed their weak emission spectra. Significantly, a strong correlation between the planarity isoalloxazine ring. For bent ring structure, ultrafast from...
Photolyase uses blue light to restore the major ultraviolet (UV)-induced DNA damage, cyclobutane pyrimidine dimer (CPD), two normal bases by splitting ring. Our earlier studies showed that overall repair is completed in 700 ps through a cyclic electron-transfer radical mechanism. However, fundamental processes, electron-tunneling pathways and ring splitting, were not resolved. Here, we use ultrafast UV absorption spectroscopy show CPD splits sequential steps within 90 electron tunnels...
We report here our systematic studies of the dynamics four redox states flavin cofactor in both photolyases and insect type 1 cryptochromes. With femtosecond resolution, we observed ultrafast photoreduction oxidized state adenine dinucleotide (FAD) subpicosecond neutral radical semiquinone (FADH•) tens picoseconds through intraprotein electron transfer mainly with a neighboring conserved tryptophan triad. Such make these forms unlikely to be functional photolyase/cryptochrome family. In...
Novel hyperspectral indices, which are the first derivative normalized difference nitrogen index (FD-NDNI) and ratio vegetation (FD-SRNI), were developed to estimate leaf content (LNC) of wheat. The field stress experiments conducted with different water application rates across growing season wheat 190 measurements collected on canopy spectra LNC under various treatments. inversion models constructed based dataset evaluate ability spectral indices LNC. A comparative analysis showed that...
In comparison with atmospheric boundary-layer winds, which are generally regarded as stationary, windstorms such hurricanes and thunderstorms/downbursts have strong nonstationary features characterized by rapid changes in wind speed direction. The averaging interval associated turbulent characteristics winds is typically varied between 10 min 1 h. A fixed (FAI), uses a constant mean to isolate the fluctuating component, has been effective characterizing winds; however, question remains...
Net ecosystem productivity (NEP) plays an important role in understanding function and the global carbon cycle. In this paper, key parameters of Carnegie Ames Stanford Approach (CASA) model, maximum light use efficiency (εmax), was optimized by using vegetation classification data. Then, NEP estimated coupling CASA geostatistical model soil respiration (GSMSR) respiration–soil heterotrophic (Rs-Rh) relationship model. The ground observations from ChinaFLUX were used to verify estimation...
ABSTRACT Endoplasmic reticulum (ER) stress signaling is an adaptive cellular response to the loss of ER Ca 2+ homeostasis and/or accumulation misfolded, unassembled, or aggregated proteins in lumen. stress-activated pathways regulate protein synthesis initiation and can also trigger apoptosis through ER-associated caspase 12. Viruses that utilize host cell as integral part their life cycle would be predicted cause some level stress. Bovine viral diarrhea virus (BVDV) a positive-stranded RNA...
The flavin cofactor in photoenzyme photolyase and photoreceptor cryptochrome may exist an oxidized state should be converted into reduced state(s) for biological functions. Such redox changes can efficiently achieved by photoinduced electron transfer (ET) through a series of aromatic residues the enzyme. Here, we report our complete characterization photoreduction dynamics with femtosecond resolution. With various site-directed mutations, identified all possible donors enzyme determined...
The primary dynamics in photomachinery such as charge separation photosynthesis and bond isomerization sensory photoreceptor are typically ultrafast to accelerate functional avoid energy dissipation. same is also true for the DNA repair enzyme, photolyase. However, it not known how photoinduced step optimized photolyase attain maximum efficiency. Here, we analyse reaction steps of ultraviolet-damaged by using femtosecond spectroscopy. With systematic mutations amino acids involved binding...
The Sichuan–Tibet railway (STR), beginning from Chengdu in Sichuan Province and ending Lhasa Tibet Autonomous Region, runs across the southeastern margin of Qinghai–Tibet Plateau (QTP). Due to intense tectonic activity, deeply incised valleys, high geostress frequent earthquakes, STR area is a typical large landslide-prone area. To gain insights into landslides along STR, an covering 3.34 × 105 km2 that extends 80–150 km on both sides was used examine spatial distribution corresponding...
Maize pollen is highly sensitive to heat and drought, but few studies have investigated the combined effects of drought on viability. In this study, pollen's structural physiological characteristics were determined after heat, stressors. Furthermore, integrated metabolomic transcriptomic analyses maize conducted identify potential mechanisms stress responses. Tassel growth spikelet development considerably suppressed, viability was negatively impacted, starch granules depleted during...
Dynamic solvation at binding and active sites is critical to protein recognition enzyme catalysis. We report here the complete characterization of ultrafast dynamics site photoantenna molecule cofactor/substrate in photolyase by examining femtosecond-resolved fluorescence entire emission spectra. With direct use intrinsic antenna cofactor chromophores, we observed local environment relaxation on time scales from a few picoseconds nearly nanosecond. Unlike conventional where Stokes shift...
Electron tunneling pathways in enzymes are critical to their catalytic efficiency. Through electron tunneling, photolyase, a photoenzyme, splits UV-induced cyclobutane pyrimidine dimer into two normal bases. Here, we report our systematic characterization and analyses of photoinitiated three transfer processes ring splitting by following the entire dynamical evolution during enzymatic repair with femtosecond resolution. We observed complete dynamics reactants, all intermediates final...