Oliver McNeilly

ORCID: 0000-0003-1183-1291
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bacterial biofilms and quorum sensing
  • Essential Oils and Antimicrobial Activity
  • Bone Tissue Engineering Materials
  • Healthcare and Environmental Waste Management
  • Carbon and Quantum Dots Applications
  • Vibrio bacteria research studies
  • Dental materials and restorations
  • Graphene and Nanomaterials Applications

University of Technology Sydney
2021-2023

Treatment of bacterial biofilms are difficult and in many cases, expensive. Bacterial naturally more resilient to antimicrobial agents than their free-living planktonic counterparts, rendering the community growth harder control. The present work described risks long-term use an important alternative antimicrobial, silver nanoparticles (NAg), for first time, on dominant mode growth.NAg could inhibit formation as well eradicating already grown biofilm Pseudomonas aeruginosa, a pathogen...

10.1186/s12951-021-01027-8 article EN cc-by Journal of Nanobiotechnology 2021-09-27

The increasing biological use of graphene-based materials has prompted research inquiries on their effects microorganisms. work herein reported different types microbiological activity reduced graphene oxide (RGO). At relatively high concentrations (200 and 400 μg/mL), RGO exhibited antibacterial the model bacterium Escherichia coli, while at lower (10 50 interestingly, no effect was observed. Instead, an increase in viable population after exposure observed, verified by colony counting...

10.1155/2021/9941577 article EN Journal of Nanomaterials 2021-04-28

This research explores the adaptive defense mechanisms of a nanosilver-resistant pathogen (NAg R ) to protect and fight off complex antimicrobial targeting silver nanoparticles. The Gram-negative bacterium Acinetobacter baumannii upregulated expression outer membrane proteins for cell surface defense, as well capsule synthesis genes. Increased abundance surface-attached biofilm colonies in NAg was linked phenotypically indicated increase integrity, with also forming more EPS, biopolymer...

10.1101/2025.01.28.635224 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-01-28

The present work describes the evolution of a resistance phenotype to multitargeting antimicrobial agent, namely, silver nanoparticles (nanosilver; NAg), in globally prevalent bacterial pathogen Acinetobacter baumannii. Gram-negative bacterium has recently been listed as critical priority requiring novel treatment options by World Health Organization. Through prolonged exposure important nanoparticle, developed mutations genes that encode protein subunits organelle structures are involved...

10.1128/spectrum.02857-22 article EN cc-by Microbiology Spectrum 2023-01-10

Bioinspired nanotopography artificially fabricated on titanium surfaces offers a solution for the rising issue of postoperative infections within orthopedics. On small scale, hydrothermal etching has proven to deliver an effective antimicrobial nanospike surface. However, translation industrial setting is limited by elevated synthesis temperature (150 °C) and associated equipment requirements. Here, first time, we fabricate surface nanostructures using comparatively milder temperatures (75...

10.1021/acsami.3c09525 article EN ACS Applied Materials & Interfaces 2023-09-22
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