- Cellular Mechanics and Interactions
- Bacterial biofilms and quorum sensing
- Cellular transport and secretion
Brandeis University
2024
Bactofilins are rigid, nonpolar bacterial cytoskeletal filaments that link cellular processes to specific curvatures of the cytoplasmic membrane. Although homologs bactofilins have been identified in archaea and eukaryotes, functional studies remained confined systems. Here, we characterize representatives two families archaeal from pleomorphic archaeon Haloferax volcanii , halofilin A (HalA) B (HalB). HalA HalB polymerize vitro, assembling into straight bundles. polymers highly dynamic...
Bactofilins are rigid, non-polar bacterial cytoskeletal filaments that link cellular processes to specific curvatures of the cytoplasmic membrane. Although homologs bactofilins have been identified in archaea and eukaryotes, functional studies remained confined systems. Here, we characterize representatives two new families archaeal from pleomorphic archaeon Haloferax volcanii , halofilin A (HalA) B (HalB). HalA HalB polymerize vitro assembling into straight bundles. polymers highly dynamic...