- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Pathogenesis and Treatment of Hiccups
- Vascular anomalies and interventions
- Inflammatory Bowel Disease
- Healthcare Systems and Public Health
- Coronary Interventions and Diagnostics
- Colorectal Cancer Screening and Detection
- Neonatal Health and Biochemistry
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Abdominal vascular conditions and treatments
- Autoimmune and Inflammatory Disorders
- Pancreatic and Hepatic Oncology Research
- Aortic aneurysm repair treatments
Central State Medical Academy
2018-2025
National Medical Research Center of Cardiology
2020-2021
State Research Center of the Russian Federation
2015
Objective: To study the condition of upper gastrointestinal mucosa, frequency bleeding, risk factors according to "REGATA" scale (2021), and assess effectiveness endoscopic hemostasis methods in patients with atherosclerosis. Materials Methods: We studied 118 (main group - MG) atherosclerosis visceral branches abdominal aorta 120 (control CG) without these but coronary artery Diagnosis erosive changes GI tract verification source bleeding were confirmed by examination. The severity ulcer was...
Introduction.Upper gastrointestinal (UGI) bleeding is a common complication of antiplatelet therapy. Data from real clinical practice that characterize the range risk factors for UGI bleeding, prophylactic proton pump inhibitors (PPIs) therapy, frequency and their long-term effects in patients with stable coronary artery disease (CAD) are limited. Aim.To identify predictors CAD, to assess role PPI prevention prognosis after bleeding. Materials methods.934 CAD (median age 61 [5368] years,...
Aim . To optimize the upper gastrointestinal bleeding (UGIB) risk scale in patients Material and methods. The UGIB was developed based on with chronic coronary artery disease (CAD) receiving long-term antiplatelet therapy. prospective REGistry of AnTithrombotic TherApy-1 REGATTA-1(ClinicalTrials.gov Identifier: NCT04347200). registry includes 934 stable CAD (men, 78,6%; median age, 61±10,7 years), 76% whom were included after elective percutaneous interventions received dual therapy for 6-12...
Aim. To establish the prevalence of atherosclerotic lesions in unpaired visceral artery branches abdominal aorta. explore features clinical presentation, state mucosa upper GI tract. Materials and methods. A total 118 patients with atherosclerosis aorta aged 45 to 89 years were examined. The comparison group included 120 without Patients both groups had coronary atherosclerosis. Ultrasound dopplerography (USDG) as a screening technique, CT angiography, MSCT aortography used verify...
Objective: To assess the alterations of gastric mucosa, its pathomorphological and functional characteristics in patients with complete erosions suffering from chronic heart failure II-III NYHA class. Materials Methods: 185 comprised main group, while control group consisted 183 incomplete stomach. Patients both groups had All underwent esophagogastroduodenoscopy white light imaging (WLI), narrow-band (NBI), ZOOM modes, as well biopsy sampling followed by examination, determination...
Aim . To study the role of von Willebrand factor (VWF) and D-dimer (DD) as predictors upper gastrointestinal bleeding (GIB) in patients with stable coronary artery disease (CAD). Material methods The included CAD who are members prospective registry long-term antithrombotic therapy (REGATTA-1) (ClinicalTrials.gov Identifier: NCT04347200). primary endpoints were actionable GIBs (Bleeding Academic Research Consortium type 2-5). Cut-off points for DD VWF determined by ROC analysis. predictive...
The article provides analysis of the study diagnostic value epithelial lesions column – a combination newest visualization methods as NBI and ZOOM with confocal laser endomicroscopy. was conducted in 202 patients aged 40–84, 47 were identified. Results preparation colon to by drugs Phospho-Soda Macrogol evaluated. obtained results allow making conclusion that use CLEM allows determining structure polyp real time regime (in vivo) increases accuracy up 96.5%, quality has decisive meaning.
The article presents the results of using a combination PPI (pantoprazole) and UDCA for treatment erosive esophagitis induced by mixed reflux in patients with coronary artery disease. A total 62 EGDS-proven were enrolled study. divided into two groups: active group (ATG) which included 34 control (CG), 28 without CAD. both groups received IPP 80 mg/day at dosage 15 mg/kg/day 12 weeks. (84 days). study showed that complete epithelialization esophageal mucosa defects was detected 100% ATG Day...
The key side effects of antiplatelet therapy are associated with the damage upper gastrointestinal tract (GIT) mucous that can lead to erosions or ulcers and specifically complicated by bleeding. Aim. To assess mucosal condition endoscopic histological methods in patients stable coronary arteries disease receiving long-term bleeding (GIB) history high risk this complication. Materials methods.The study included from single-center prospective registry antithrombotic REGATTA-1. gastric mucosa...