A5045212757- Hepatitis B Virus Studies
- Hepatitis Viruses Studies and Epidemiology
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Hepatitis C virus research
- COVID-19 Impact on Reproduction
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Preterm Birth and Chorioamnionitis
- Maternal Mental Health During Pregnancy and Postpartum
- Global Maternal and Child Health
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Pregnancy-related medical research
- Liver Disease Diagnosis and Treatment
- Gestational Diabetes Research and Management
- Pregnancy and Medication Impact
- Genomic variations and chromosomal abnormalities
- Smoking Behavior and Cessation
- Neonatal Respiratory Health Research
- HIV/AIDS Research and Interventions
- Urological Disorders and Treatments
- Pelvic and Acetabular Injuries
- Genomics and Rare Diseases
Chinese University of Hong Kong
1982-2025
University of Hong Kong
2016-2025
Queen Mary Hospital
2016-2025
Beijing Obstetrics and Gynecology Hospital
2021
Birmingham Women’s and Children’s NHS Foundation Trust
2018-2019
Children’s Foundation
2019
Royal Oldham Hospital
2014
Université Paris Cité
2011
Délégation Paris 5
2011
Prince of Wales Hospital
2006
✓ The indications for surgical fusion, as opposed to halo fixation, in the management of cervical spine injury are still unclear. At St. Louis University Medical Center a conservative protocol has been adopted treat almost all fractures with fixation. To determine what factors have contributed failure records and radiographs patients injuries who were treated at that institution between 1984 1986 reviewed. During this interval, 124 treated, consisting 93 men 31 women 6 94 years old. Of...
Introduction:Owing to the coronavirus disease 2019 outbreak Hong Kong hospitals have suspended visiting periods and made mask wearing mandatory.In obstetrics, companionship during childbirth has been prenatal exercises, antenatal talks, hospital tours, postnatal classes cancelled.The aim of present study was investigate effects these restrictive measures on delivery plans risks postpartum depression. Methods:We compared pregnancy data Edinburgh Postpartum Depression Scale (EPDS) scores women...
The maternal immune system needs to tolerate the semi-allogeneic fetus in pregnancy. adaptation occurs locally at maternal-fetal interface as well systemically through circulation. Failure paternal antigens may result pregnancy complications, such loss and pre-eclampsia. However, mechanism that regulates tolerance, especially systemic level, is still an enigma. Here we report first-trimester placenta-derived exosomes (pEXOs) contribute tolerance by reprogramming circulating monocytes.pEXOs...
Early-onset preeclampsia (EOPE) is a severe pregnancy complication associated with defective trophoblast differentiation and functions at implantation, but manifestation of its phenotypes in late pregnancy. There no reliable method for early prediction treatment EOPE. Adrenomedullin (ADM) an abundant placental peptide Integrated single-cell sequencing spatial transcriptomics confirm high ADM expression the human villous cytotrophoblast syncytiotrophoblast. The levels chorionic villi serum...
Fetal hyperthyroidism can occur secondary to maternal autoimmune hyperthyroidism. The thyroid-stimulating hormone receptor antibody (TRAb) transferred from the mother fetus stimulates fetal thyroid and causes thyrotoxicosis. Fetuses with this condition are difficult detect, especially after Graves disease therapy. Here, we present two cases of hypothyroidism review assessment intrauterine therapy for Both women were referred at 22+ 23+ weeks gestation abnormal ultrasound findings, including...
ABSTRACT Objective To investigate the association of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral load and infection‐to‐delivery interval with maternal cord serum concentrations anti‐SARS‐CoV‐2 immunoglobulin G (IgG) antibodies transplacental transfer ratio in pregnant women active or recovered SARS‐CoV‐2 infection. Methods This was a prospective case series consecutive laboratory‐confirmed infection between 27 March 2020 24 January 2021. We collected information...
Abstract Pregnancy involves a wide range of adaptations in the maternal body. Maternal immune tolerance toward foreign fetus is critical for successful pregnancy. Decidual macrophages are primary antigen-presenting and phagocytic cells responsible antigen presentation apoptotic cell removal. Their phenotype changes dynamically during Placenta-derived exosomes small vesicles carrying active biological molecules such as microRNAs, proteins, lipids. The placenta-derived have been implicated...
Unrecognized diabetes during pregnancy could pose serious maternal and neonatal complications. A HbA1c level of ≥ 6.5% was used to diagnose both in non-pregnant individuals (DIP). Since the be influenced by physiological changes, optimal cut-off early detect women with DIP associated complications remains unclear. To evaluate diagnostic performance various levels, as well identify mothers diagnosed gold standard 75grams oral glucose tolerance test (OGTT) before 24 weeks gestation. We also...
Hepatitis B virus (HBV) infection remains a global threat and causes substantial disease burden.The World Health Organization has set goal to eliminate viral hepatitis as public health by 2030.Mother-to-child transmission (MTCT) is the main route of HBV transmission.Most MTCT cases can be prevented timely active passive immunisation at birth, but failed immunoprophylaxis in infants continues occur among women with high load during pregnancy.Hepatitis activity infected mothers should assessed...
Importance Reducing maternal mortality is a global objective. The ratio (MMR) low in Hong Kong, China, but there has been no local confidential enquiry into death, and underreporting likely. Objective To determine the causes timing of death Kong identify deaths their that were missed by vital statistics database. Design, Setting, Participants This cross-sectional study was conducted among all 8 public maternity hospitals Kong. Maternal identified using prespecified search criteria, including...