- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Hernia repair and management
- Gallbladder and Bile Duct Disorders
- Intestinal and Peritoneal Adhesions
- Gastrointestinal disorders and treatments
- Abdominal Surgery and Complications
- Esophageal and GI Pathology
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Testicular diseases and treatments
- Neuroblastoma Research and Treatments
- Pelvic and Acetabular Injuries
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Treatments and Studies
- Minimally Invasive Surgical Techniques
- Science and Science Education
- Advanced Physical and Chemical Molecular Interactions
- Gastroesophageal reflux and treatments
- Advanced Polymer Synthesis and Characterization
- Biliary and Gastrointestinal Fistulas
- Material Properties and Applications
Hospital Israelita Albert Einstein
2016-2024
Universidade Federal de São Paulo
2012-2022
Fundação de Apoio à Universidade Federal de São Paulo
2002-2018
Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia
2010
Essen University Hospital
2010
Thomson Reuters (United States)
2010
Impact
2010
Canadian Association for Laboratory Animal Science
2009
Union des Industries Ferroviaires Européennes
1998-2008
Associação Paulista de Medicina
1985-2003
The solid pseudopapillary neoplasm is a rare tumor of the pancreas. However, it´s etiology still maintain discussions.To analyze clinical data, diagnosis and treatment.A retrospective study medical records all patients treated from January 1997 until July 2015.Were identified 17 cases. Most were women (94.11%) average age was 32.88 years. main complaint abdominal mass (47.05%). most frequent location in body/tail pancreas (72.22%) frequently performed surgery distal pancreatectomy with...
Background. Because of the worse results from retransplantation in relation to initial liver transplantation, there is a need refine indication for retransplantation, such that fair distribution this benefit obtained. Methods. This was study 139 patients who underwent retransplantation. Thirty variables were studied: 18 relating recipient and 12 donor. All independent initially compared with length survival using univariate analyses. Variables presenting significance dependent variable...
Compare, in a rabbit model, the inflammatory response and adhesions formation following surgical fixation of polypropilene Vypro mesh inguinal preperitoneal space.Fourteen male New Zealand rabbits, weighing between 2.000 to 2.500 g were used. A midline incision was made peritoneal cavity exposed. The 2.0 x 1.0 cm polypropylene fixed left flank secured margins with 3-0 prolene separate pattern. In right flank, II sewn same way. After post period, animals again anesthetized underwent...
Abstract Die radikalische Polymerisation von Äthylen und dessen Copolymerisation mit Vinyl‐acetat Vinylchlorid wurden untersucht. Kettenübertragungskonstante durch das Monomere erwies sich bei der als vom Druck abhängig. Eine Druckabhängigkeit wurde auch für die Copolymerisationsparameter festgestellt. Aus dem Stadium IR‐Spektren Copolymeren folgt, daß im Laufe Vinylacetat Reaktion anomalen Anlagerung (die Bildung Struktureinheiten CH 2 CHRCH CHRCH ) eine wesentliche Rolle spielt. Dieser...
To evaluate the prognostic significance and correlation with staging degree of cell differentiation tumoral expression proteins c-erbB-2 E-cadherin, in patients colorectal adenocarcinoma.The study included 117 an average age 63.1 years follow-up duration 28.1 months. The disease-free interval, survival, incidence recurrence specific mortality were evaluated. anti-oncoprotein antibodies (Dako) utilized via streptavidin-biotin technique. Samples considered to be positive for if 10% or more...
PURPOSE: To investigate the effects of polypropylene mesh, implanted by inguinotomy, in spermatic funiculus, epididium and testis dogs. METHODS: Eighteen dogs were considered (12-23 Kg), separated three groups. Group A (n=7): left side (with mesh) versus right (without mesh); B C (n=4): without any surgical manipulation (control group). After being observed for 60 days, animals subjected to bilateral removal that submitted histological analysis. During re-operation, a macroscopic evaluation...
PURPOSE: Evaluate short results after fundoplication procedure, concerning the division of gastric vessels. METHODS: A prospective randomization 90 patients with indication for hiatoplasty and total fundus mobilization was performed. They were divided into two groups: no SGV (group A, n= 46) (Group B, n=44), although in both groups mobilized to perform a floppy valve. Early outcome clinical follow up (1 year) observed. RESULTS: Both similar regarding preoperative parameters severity...
To evaluate testicular volume and arterial flow in patients undergoing surgical correction for inguinal hernia, with polypropylene prosthesis.This was an observational prospective clinical study on 39 male unilateral hernia of types III A B according to the Nyhus classification who underwent implantation a prosthesis by means Lichtenstein technique. The were evaluated using Doppler ultrasound before operation selectively at third sixth months after operation. variables studied volume,...
BACKGROUND: Gallbladder carcinoma presents a dismal prognosis. Choice treatment is surgical resection that associated high levels of both morbidity and mortality. Best knowledgement prognostic factors may result better selection patients either for or multimodal treatment. AIM: To evaluate tecidual immunoexpression P53, E-cadherin, Cox-2, EGFR proteins to correlate these findings with resected gallbladder adenocarcinoma survival. METHODS: Clinical, laboratorial, surgical, anatomopathological...
In spite its relative rarity, gallbladder adenocarcinoma is a neoplasm who presents an aggressive biologic behavior. The single curative treatment has been radical surgical resection with free margin. Prognostic factors studied because are very important to identify long-term survival patients which may benefit of resection.To evaluate prognostic predictors from cancer.The medical records all that presented confirmed histological diagnosis operated over 14 year period were identified and...
Prognostic differences between major histologic gastric cancer groups, intestinal and diffuse are uncertain, since cellular components in each of them possibly have different behaviors.We reviewed 198 patients charts diagnosed from January 2003 to December 2015 a tertiary hospital. Multivariate Cox proportional survival models were used evaluate the impact groups on overall survival.About third had signet-ring cell carcinoma (SRCC). In comparison subtypes, SRCC worst prognosis all. The...
PURPOSE: To analyze the correlation between p53 and bcl-2 expression colorectal adenocarcinoma staging prognosis. METHODS: This was a retrospective series of 125 patients (67 women 58 men; ages 30-87 years) who underwent surgery with curative intent. The mean follow-up 28.5 months (range: 2-96 months). TNM staging, tumor recurrence, survival cancer-related mortality were analyzed. Immunoreactivity evaluated using DO7 (Dako) for K492 bcl-2. Tumors accumulation staining cytoplasmic or nuclear...
To develop an experimental model of gastroesophageal reflux in rats.Sixty Wistar rats underwent surgery and were assigned to one the three groups twenty animals each. The group A total esophageal myectomy and, (B), partial myectomy. third was control (C). contrast radiographic study esophagus performed evaluate reflux. anatomopathological used esophagitis.During 30-day postoperative follow-up, 14 presented with barium esophagus. presence observed 7 B 2 group. result histopathology...
To compare the effect of parenteral versus enteral nutritional support in severe acute pancreatitis, with respect to efficacy, safety, morbidity, mortality and length hospitalization.The study was comprised 31 patients, divided into a group (n=16) an (n=15), who met severity criteria for abdominal tomography (Balthazar classes C, D, E). The patients were compared by demographics, disease etiology, antibiotic prophylaxis, use or not somatostatin, support, complications progression.There no...
PURPOSE: To evaluate of postoperative adhesion prevention and inflammatory response to polypropylene mesh, coated with reabsorbable hydrogel polyethylene glycol (Coseal®) in contact small bowel an experimental model rabbits. METHODS: Twenty female rabbits underwent laparotomy implant two meshes, 2x1cm, the right left flanks. The mesh was protected Coseal® spray (Group 1) received no treatment after implantation 2). Thirty days implantation, laparoscopy for analysis; prosthesis were removed...
Objective To determine the overall survival of patients with advanced pancreatic cancer and evaluate factors that impact prognosis in a private center.Methods Data from Hospital Cancer Registry at Israelita Albert Einstein were retrospectively collected. The enrolled had metastatic diagnosis or earlier staging subsequent recurrence. Cases neuroendocrine tumors excluded.Results A total 65 evaluated, including 63 adenocarcinoma. median for all stages was 20.7 months (95%CI: 15.6-25.7), while...
Insulinomas are rare endocrine pancreatic tumors whose incidence has been increasing in recent years owing to early detection by clinical and radiologic, such as remote neural monitoring, computed tomography (CT), ultrasound (US) findings. The classical treatment consists of open surgical resection, which is associated with relative morbidity mortality rates. aim this paper was present 5 patients who were diagnosed insulinomas that treated laparoscopic resection. Five (5) patients, ranging...
von Hippel-Lindau syndrome (VHLS) is a rare, autosomal dominant genetic disease with high penetrance and variable phenotypic expression caused by variants in the VHL gene. VHLS associated presence of vascular tumors, often hemangioblastoma central nervous system, retina, or spinal cord and, less frequently, pancreatic cystic neoplasm, neuroendocrine tumor, clear cell carcinoma kidney, endolymphatic sac pheochromocytoma, paraganglioma. The authors report case patient rare pathogenic variant...
The occurrence of severe dysphagia after laparoscopic total fundoplication is currently an important factor associated with loss quality life in patients undergoing this modality treatment for gastroesophageal reflux disease.Compare the incidence and evaluate causes postoperative (LTF) without short gastric vessels division, using anterior wall (Rossetti LTF) or posterior walls (Nissen LTF).Analysis data 289 submitted to LTF division from January 2004 2012, a minimum follow-up 6 months....