A5026121141- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Obesity and Health Practices
- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Fatty Acid Research and Health
- Infant Nutrition and Health
- Thyroid Disorders and Treatments
- Neonatal Respiratory Health Research
- Child Nutrition and Water Access
- Cerebral Palsy and Movement Disorders
- Diet and metabolism studies
- Child and Adolescent Health
- Gut microbiota and health
- Childhood Cancer Survivors' Quality of Life
- Infant Development and Preterm Care
- Effects of Vibration on Health
- Growth Hormone and Insulin-like Growth Factors
- Ecology and Vegetation Dynamics Studies
- Bird parasitology and diseases
University of Auckland
2016-2025
Uppsala University
2017-2025
Chiang Mai University
2020-2025
Starship Children's Health
2023
Children's Hospital of Zhejiang University
2019-2022
Ministry of Health
2007-2021
Guerbet (France)
2021
Taranaki Base Hospital
2020
Weatherford College
2020
Jikei University School of Medicine
2017
Olive plant leaves (Olea europaea L.) have been used for centuries in folk medicine to treat diabetes, but there are very limited data examining the effects of olive polyphenols on glucose homeostasis humans.To assess supplementation with leaf (51.1 mg oleuropein, 9.7 hydroxytyrosol per day) insulin action and cardiovascular risk factors middle-aged overweight men.Randomized, double-blinded, placebo-controlled, crossover trial New Zealand. 46 participants (aged 46.4 ± 5.5 years BMI 28.0 2.0...
Abstract We evaluated the quality and content of fish oil supplements in New Zealand. All encapsulated marketed Zealand were eligible for inclusion. Fatty acid was measured by gas chromatography. Peroxide values (PV) anisidine (AV) total oxidation (Totox) calculated. Only 3 32 contained quantities eicosapentaenoic (EPA) docosahexaenoic (DHA) that equal or higher than labelled content, with most products tested (69%) containing <67%. The vast majority exceeded recommended levels markers....
GH therapy requires daily injections over many years and compliance can be difficult to sustain. As growth hormone (GH) is expensive, non-compliance likely lead suboptimal growth, at considerable cost. Thus, we aimed assess the rate of children adolescents with treatment in New Zealand.This was a national survey compliance, which all receiving government-funded for four-month interval were included. Compliance defined as ≥ 85% adherence (no more than one missed dose week on average)...
Phenolic compounds derived from the olive plant (Olea europaea L.), particularly hydroxytyrosol and oleuropein, have many beneficial effects in vitro. Olive leaves are richest source of phenolic compounds, leaf extract (OLE) is now a popular nutraceutical taken either as liquid or capsules. To quantify bioavailability metabolism oleuropein when OLE, nine volunteers (five males) aged 42.8 ± 7.4 years were randomized to receive capsulated OLE single lower (51.1 mg 9.7 hydroxytyrosol) higher...
<h3>Importance</h3> Treatment of pediatric obesity is challenging. Preclinical studies in mice indicated that weight and metabolism can be altered by gut microbiome manipulation. <h3>Objective</h3> To assess efficacy fecal transfer (FMT) to treat adolescent improve metabolism. <h3>Design, Setting, Participants</h3> This randomized, double-masked, placebo-controlled trial (October 2017-March 2019) with a 26-week follow-up was conducted among adolescents aged 14 18 years body mass index (BMI;...
Objective We aimed to assess the effects of age, sex, body mass index (BMI), and anatomical site on skin thickness in children adults with diabetes. Methods studied 103 otherwise healthy adolescents type 1 diabetes aged 5–19 years, 140 2 20–85 years. The thicknesses both dermis subcutis were assessed using ultrasound a linear array transducer, abdominal thigh skin. Results There was an age-related thickening (p<0.0001) (p = 0.013) adolescents. Girls displayed substantial pubertal increase...
Abstract We assessed whether omega-3 index (red blood cell concentrations of eicosapentaenoic acid (EPA) and docosahexaenoic (DHA)) was associated with insulin sensitivity other metabolic outcomes in 47 overweight men aged 46.5 ± 5.1 years. Participants were twice, 16 weeks apart. Insulin by the Matsuda method from an oral glucose tolerance test. Linear associations examined; stratified analyses carried out participants separated according to index: lower tertiles (LOI; n = 31) highest...
We assessed the incidence of diabetic ketoacidosis (DKA) in children aged <15 years with newly diagnosed type 1 diabetes mellitus (T1DM) Auckland Region (New Zealand) 1999-2013, a retrospective review complete regional cohort. DKA and its severity were classified according to ISPAD 2014 guidelines. Of 730 presenting new-onset T1DM over 15-year time period, 195 cases had any (27%). There was no change or proportion severe at presentation. The among <2.0 (n = 40) 53% compared 25% for those...
BackgroundBirth by caesarean section (CS) is associated with aberrant gut microbiome development and greater disease susceptibility later in life. We investigated whether oral administration of maternal vaginal microbiota to infants born CS could restore their a pilot single-blinded, randomised placebo-controlled trial (Australian New Zealand Clinical Trials Registry, ACTRN12618000339257).MethodsPregnant women scheduled for underwent comprehensive antenatal pathogen screening. At birth,...
Abstract Background Donor selection is an important factor influencing the engraftment and efficacy of fecal microbiota transplantation (FMT) for complex conditions associated with microbial dysbiosis. However, degree, variation, stability strain have not yet been assessed in context multiple donors. Methods We conducted a double-blinded randomized control trial FMT 87 adolescents obesity. Participants were to receive multi-donor (capsules containing four sex-matched lean donors) or placebo...
Abstract: In times of biodiversity crisis there is an increasing need for faster and cheaper methods by which to achieve conservation goals. This situation especially troublesome invertebrates, the use morphospecies instead taxonomic species has been proposed as a way around constraints in particular situations. We conducted study modified native shrubland on New Zealand's South Island we sampled Lepidoptera, Coleoptera, Araneae autumn beating pitfall traps. All specimens were separated into...
Recent reports suggest that the incidence of congenital hypothyroidism (CHT) is increasing in some countries. The etiology this change unclear, and it may relate to changes screening thresholds. We aimed determine whether CHT New Zealand has changed ethnic-specific rates subtypes have also changed.The neonatal TSH-based program prospectively identified cases using same assay thresholds since 1993. Thyroid scintiscans are routinely recommended. retrospectively all requiring levothyroxine...
BackgroundPreterm birth is associated with abnormalities in growth, body composition, and metabolism during childhood, but adult data are scarce none exist for their offspring. We therefore aimed to examine composition cardiovascular risk factors adults born preterm children. MethodsA cohort of 52 (aged 35.7 years, 54% female, 31 preterm) term-born children (n=61, aged 8.0 60% from a parent) were studied. Auxology (whole-body dual-energy X-ray absorptiometry) measured, fasting blood samples...
We assessed the incidence of infants born small-for-gestational-age (SGA) and large-for-gestational-age (LGA) in an Italian cohort over 20 years (1993–2013). Furthermore, we investigated maternal factors associated with SGA LGA births. A retrospective review obstetric records was performed on Chieti (Italy) covering every 5th year a 20-year period, specifically examining data for 1993, 1998, 2003, 2008, 2013. Infants birthweight <10th percentile were defined as SGA, those >90th LGA. Data...
STUDY QUESTIONWhat are the lifestyle choices and dietary aspects of women about to undergo fertility treatment in New Zealand?
Abstract While there is evidence that being born large-for-gestational-age (LGA) associated with an increased risk of obesity later in life, the data are conflicting. Thus, we aimed to examine associations between proportionality at birth and adulthood. This was a retrospective study using recorded Swedish Birth Register. Anthropometry adulthood assessed 195,936 pregnant women 10–12 weeks gestation. All were term (37–41 gestation). LGA defined as weight and/or length ≥2.0 SDS. Women...
Abstract We performed a clinical trial on the effects of whole-body vibration training (WBVT) muscle function and bone health adolescents young adults with cerebral palsy. Forty participants (11.3–20.8 years) mild to moderate palsy (GMFCS II–III) underwent 20-week WBVT plate for 9 minutes/day 4 times/week at 20 Hz (without controls). Assessments included 6-minute walk test, DXA, lower leg pQCT scans, (force plate). Twenty weeks were associated increased lean mass in total body (+770 g; p =...
The use of morphospecies as surrogates for taxonomic species has been proposed an alternative to overcome the identification difficulties associated with many invertebrate studies, such biodiversity surveys. Hymenoptera specimens were collected by beating and pitfall traps, separated into a non-specialist no prior training, later identified expert taxonomist. number was 37 42, respectively, representing underestimation error 12%. Different families presented varying levels difficulty,...
Despite newborn screening and early levothyroxine replacement, there are continued reports of mild neurocognitive impairment in children with congenital hypothyroidism (CHT). In Auckland, New Zealand, cases identified by a neonatal program rapid institution high-dose replacement (10–15 μg/kg·d), producing prompt normalization thyroid function. Subsequently, frequent monitoring dose alterations performed for 2 years. We aimed to assess whether the Auckland treatment strategy prevents...