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Ying H. Kan

ORCID: 0000-0003-1235-2364
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A5007555960
Research Areas
  • COVID-19 Clinical Research Studies
  • Diabetes and associated disorders
  • Single-cell and spatial transcriptomics
  • SARS-CoV-2 and COVID-19 Research

Kiel University
 2020

 Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19
OPENALEX - Publications 
Joana P. Bernardes Neha Mishra Florian Tran Thomas Bahmer Lena Best and 95 more Johanna I. Blase Dora Bordoni Jeanette Franzenburg Ulf Geisen Jonathan Josephs‐Spaulding Philipp Köhler Axel Künstner Elisa Rosati Anna C. Aschenbrenner Petra Bächer Nathan Baran Teide Jens Boysen Burkhard Brandt Niklas Bruse Jonathan Dörr Andreas Dräger Gunnar Elke David Ellinghaus Julia Fischer Michael Förster André Franke Sören Franzenburg Norbert Frey Anette Friedrichs Janina Fuß Andreas Glück Jacob Hamm Finn Hinrichsen Marc P. Hoeppner Simon Imm Ralf Junker Sina Kaiser Ying H. Kan Rainer Knoll Christoph Lange Georg Laue Clemens Lier Matthias Lindner Γεώργιος Μαρίνος Robert Markewitz Jacob Nattermann Rainer Noth Peter Pickkers Klaus F. Rabe Alina Renz Christoph Röcken Jan Rupp Annika Schaffarzyk Alexander Scheffold Jonas Schulte-Schrepping Domagoj Schunk Dirk Skowasch Thomas Ulas Klaus‐Peter Wandinger Michael Wittig Johannes Zimmermann Hauke Busch Bimba F. Hoyer Christoph Kaleta Jan Heyckendorf Matthijs Kox Jan Rybniker Stefan Schreiber Joachim L. Schultze Philip Rosenstiel Nicholas E. Banovich Tushar Desai Oliver Eickelberg Muzlifa Haniffa Péter Horváth Jonathan A. Kropski Robert Lafyatis Joakim Lundeberg Kerstin B. Meyer Martijn C. Nawijn Marko Nikolić José Ordovas Montañes Dana Pe’er Purushothama Rao Tata Emma L. Rawlins Aviv Regev Paul A. Reyfman Christos Samakovlis Joachim L. Schultze Alex K. Shalek Douglas P. Shepherd Jason R. Spence Sarah A. Teichmann Fabian J. Theis Alexander M. Tsankov Maarten van den Berge Michael von Papen Jeffrey A. Whitsett Laure‐Emmanuelle Zaragosi Angel Angelov

10.1016/j.immuni.2020.11.017 article EN publisher-specific-oa Immunity 2020-11-26
 Longitudinal multi-omics analysis identifies responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories
OPENALEX - Publications 
Joana P. Bernardes Neha Mishra Florian Tran Thomas Bahmer Lena Best and 65 more Johanna I. Blase Dora Bordoni Jeanette Franzenburg Ulf Geisen Jonathan Josephs‐Spaulding Philipp Köhler Axel Künstner Elisa Rosati Anna C. Aschenbrenner Petra Bächer Nathan Baran Teide Jens Boysen Burkhard Brandt Niklas Bruse Jonathan Dörr Andreas Dräger Gunnar Elke David Ellinghaus Julia Fischer Michael Förster André Franke Sören Franzenburg Norbert Frey Anette Friedrichs Janina Fuß Andreas Glück Jacob Hamm Finn Hinrichsen Marc P. Hoeppner Simon Imm Ralf Junker Sina Kaiser Ying H. Kan Rainer Knoll Christoph Lange Georg Laue Clemens Lier Matthias Lindner Γεώργιος Μαρίνος Robert Markewitz Jacob Nattermann Rainer Noth Peter Pickkers Klaus F. Rabe Alina Renz Christoph Röcken Jan Rupp Annika Schaffarzyk Alexander Scheffold Jonas Schulte-Schrepping Domagoj Schunck Dirk Skowasch Thomas Ulas Klaus‐Peter Wandinger Michael Wittig Johannes Zimmermann Hauke Busch Bimba F. Hoyer Christoph Kaleta Jan Heyckendorf Matthijs Kox Jan Rybniker Stefan Schreiber Joachim L. Schultze Philip Rosenstiel

Abstract The pandemic spread of the potentially life-threatening disease COVID-19 requires a thorough understanding longitudinal dynamics host responses. Temporal resolution cellular features associated with severe trajectory will be pre-requisite for finding outcome predictors. Here, we performed multi-omics study using two-centre German cohort 13 patients (from Cologne and Kiel, 1). We analysed bulk transcriptome, DNA methylome, single-cell transcriptome (>358,000 cells, including BCR...

10.1101/2020.09.11.20187369 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-09-18
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