A5100863840- Metal and Thin Film Mechanics
- Semiconductor materials and devices
- Advanced SAR Imaging Techniques
- Copper Interconnects and Reliability
- Radar Systems and Signal Processing
- Computational Drug Discovery Methods
- Geoscience and Mining Technology
- Geomechanics and Mining Engineering
- Target Tracking and Data Fusion in Sensor Networks
- Non-Invasive Vital Sign Monitoring
- Nonlinear Photonic Systems
- Wireless Sensor Networks and IoT
- Aerodynamics and Fluid Dynamics Research
- Ocular Surface and Contact Lens
- Composite Structure Analysis and Optimization
- Advancements in Materials Engineering
- Computational Geometry and Mesh Generation
- Advanced Combustion Engine Technologies
- Face and Expression Recognition
- Technology and Security Systems
- Thermal and Kinetic Analysis
- Geophysical Methods and Applications
- Composite Material Mechanics
- 3D Shape Modeling and Analysis
- Energetic Materials and Combustion
University of Electronic Science and Technology of China
2010-2025
Shandong University of Traditional Chinese Medicine
2024-2025
China Academy of Chinese Medical Sciences
2025
Taiyuan Normal University
2017
Lebanese International University
2011
University of Science and Technology Liaoning
2008
Hsin Sheng College of Medical Care and Management
2003
P38α has been identified as a key target for drug design to treat wide range of diseases. In this study, multiple independent Gaussian accelerated molecular dynamics (GaMD) simulations, deep learning (DL), and the mechanics generalized Born surface area (MM-GBSA) method were used investigate binding mechanism inhibitors (SB2, SK8, BMU) DFG-in DFG-out clarify effect conformational differences in on inhibitor binding. GaMD trajectory-based DL effectively important functional domains, such...
BACE1 has been regarded as an essential drug design target for treating Alzheimer's disease (AD). Multiple independent Gaussian accelerated molecular dynamics simulations (GaMD), deep learning (DL), and mechanics general Born surface area (MM-GBSA) method are integrated to elucidate the mechanism underlying effect of D93 D289 protonation on binding inhibitors OV6 4B2 BACE1. The GaMD trajectory-based DL successfully identifies significant function domains. Dynamic analysis shows that strongly...
TaN thin films were deposited on Al 2 O 3 wafers by DC reactive magnetron sputtering. The composition control nitrogen partial flux in the working gas and electrical properties of samples investigated detail. results show that atomic number ratio Ta to N can be adjusted from 4 0.88, corresponding contents 20 at.% 53 at.%, adjusting 2% 6%. main phases x are hexagonal , body centered cubic 10 face at lower (lower than 28 at.%). However, higher (higher at.%), orthorhombic 5 phase gradually...
Al/TaN x multilayers were deposited on Al 2 O 3 wafers by DC reactive magnetron sputtering. Microstructure and electrical properties of the samples investigated in detail. The results show that more compact smoother surfaces than TaN thin films can be obtained multilayers. Metal phases precipitate out from all multilayer samples. main are poor nitrogen when sputtered at lower partial flux. However, rich gradually higher With increase flux to 6%, resistivity increases 640 1170 μΩ · cm,...
Although China's economy has maintained rapid growth since 21st century, the problem of environmental pollution become increasingly serious. Environmental a serious impact on people in all aspects clothing, food, housing and transportation. Based panel data 31 provinces regions China from 2005 to 2017, this paper establishes fixed-effect model divides into three central, east west analyzes population aging expenditure social medical insurance funds (SMIF). The study found that more severe...
Aluminium doping TaN x thin films were deposited on Al 2 O 3 ceramic wafers by DC reactive magnetron sputtering. The influences of nitrogen partial flux the phase structures and electrical properties samples investigated in detail. results show that main phases are gradually changed from poor to rich with increase flux. deposition rate is decreased With flux, resistivity absolute value temperature coefficient resistance (TCR) slowly at lower then remarkably higher These experimental can be...
Cognitive radar automatically adjusts its waveform via ceaseless interaction with the environment and learning from experience. The development of cognitive has been attracting much attention in improving tracking performance. In this paper, we propose an intelligent target strategy based on variable nonlinear frequency modulated waveforms (NLFM). considers combination constant velocity (CV), acceleration (CA), turning (CT) motion for high maneuvering targets. A library NLFM is constructed...