- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Multiple Myeloma Research and Treatments
- Protein Degradation and Inhibitors
- Bone Tumor Diagnosis and Treatments
- Soft tissue tumor case studies
- Histiocytic Disorders and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Bone health and osteoporosis research
- Vasculitis and related conditions
- Peptidase Inhibition and Analysis
- Cardiac Valve Diseases and Treatments
- Parathyroid Disorders and Treatments
- Vitamin D Research Studies
- Peripheral Neuropathies and Disorders
- Bone health and treatments
- Infectious Aortic and Vascular Conditions
- Oral and Maxillofacial Pathology
- Diagnosis and Treatment of Venous Diseases
University of Oxford
2023-2025
Abstract Purpose To describe diagnostic approaches and management strategies for patients with primary hyperparathyroidism (PHPT) recent fracture in England. Methods We developed a survey based on patient at high risk new diagnosis of probable PHPT. The was circulated among 50 secondary care professionals identified by the Society Endocrinology Calcium Bone special interest group. Descriptive statistics, combinatorial, thematic analyses were employed. Results In fracture, 54% respondents...
Reducing delayed diagnosis is a significant healthcare priority for individuals with rare diseases. Fibrous Dysplasia/ McCune Albright Syndrome (FD/MAS) bone disease caused by somatic activation mutations of NASA. FD/MAS has broad clinical phenotype reflecting variable involvement bone, endocrine and other tissues, distribution severity. The likely to prolong the diagnostic journey patients further.
<title>Abstract</title> <bold>Objectives</bold> Thoracic aortic aneurysms and dissections provide a complex surgical cohort termed major surgery. Regular follow-up at specialist clinics with cross-sectional imaging is recommended. Identifying risk factors that lead to re-operations as well the requirement for appropriate length of remain points debate. <bold>Methods</bold> Patients undergoing any operation performed single centre from January 2012 December 2022 were retrospectively reviewed....
Aortitis, defined as inflammation of the aorta, can lead to aneurysms and dissections. Intra-operative sampling is essential for diagnosis, with many cases presenting asymptomatically clinically isolated aortitis. Previous studies investigating aortitis in major aortic surgery have been limited by low intra-operative sampling. We performed an 11-year, retrospective, cross-sectional study investigate true prevalence thoracic dissections analysing all operations a single centre. collected...
Thoracic aortic aneurysms and dissections provide a complex surgical cohort termed thoracic surgery. Regular follow-up at specialist clinics with cross-sectional imaging is recommended. Identifying risk factors that lead to re-operations as well the requirement for appropriate length of remain points debate. Patients undergoing surgery performed single centre from January 2012 December 2022 were retrospectively reviewed. The clinical information, operative details, histological reports,...
Late presentation of multiple myeloma (MM) heightens the risk complication risks, including end-organ damage. This study aimed to: 1) detail diagnostic journey MM patients, encompassing symptoms, initial diagnoses, and healthcare professionals met; 2) establish median duration from symptom onset to diagnosis; 3) examine factors linked timely diagnosis within 12 weeks. A total 300 adults self-reporting were analysed Rare Undiagnosed Diseases cohort Study (RUDY). The RUDY is a web-based...
Abstract Background Reducing delayed diagnosis is a significant healthcare priority for individuals with rare diseases. Fibrous Dysplasia/ McCune Albright Syndrome (FD/MAS) bone disease caused by somatic activation mutations of GNASa. FD/MAS has broad clinical phenotype reflecting variable involvement bone, endocrine and other tissues, distribution severity. The likely to prolong the diagnostic journey patients further. Aim To describe time from symptom onset final in living FDMAS. Methods...