A5046948625- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Lipoproteins and Cardiovascular Health
- Heart Failure Treatment and Management
- Ferroptosis and cancer prognosis
- Cancer Research and Treatments
- Cardiac Health and Mental Health
- Dementia and Cognitive Impairment Research
- Ruminant Nutrition and Digestive Physiology
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Health Systems, Economic Evaluations, Quality of Life
- interferon and immune responses
- Click Chemistry and Applications
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cytokine Signaling Pathways and Interactions
- Cancer Genomics and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Reproductive Physiology in Livestock
- Diversity and Career in Medicine
- Fish biology, ecology, and behavior
- Cardiovascular Function and Risk Factors
- Immunotherapy and Immune Responses
- Radiomics and Machine Learning in Medical Imaging
Healthy Start
2025
Micron (United States)
2025
Universidade Estadual Paulista (Unesp)
2024
Hospital Israelita Albert Einstein
2013-2023
Ochsner Health System
2021-2023
Hospital Municipal São José
2023
School District of Lee County
2022
Universidad de Costa Rica
2022
Centro Universitário Sant’Anna
2022
Universidade Nilton Lins
2022
Purpose Patients with acute myocardial infarction (AMI) and respiratory impairment may be treated either invasive or non-invasive mechanical ventilation (MV). However, there has been little testing of MV in the setting AMI. Our objective was to evaluate incidence associated clinical outcomes patients AMI who were MV. Methods This a retrospective observational study which consecutive (n = 1610) enrolled. The association between exclusively MV, assessed by multivariable models. Results...
Failure-to-rescue refers to the rate of failure amongst healthcare teams in reversing complications that occur during a patient's hospitalization. This study aimed investigate failure-to-rescue following coronary artery bypass grafting (CABG). Cross-sectional cohort multicenter database "Registro Paulista de Cirurgia Cardiovascular II" (REPLICCAR II), which includes data from nine reference centers for cardiac surgery São Paulo State. The population included patients > 18 years age who had...
High rehospitalization rates and limited access to cardiac rehabilitation characterize heart failure in South America. This study highlights the significant barriers faced by patients, including lack of energy, awareness, accessibility. Despite these challenges, professional exercise supervision has reduced readmission more than 50%, underscoring its importance. ■ Barriers rehabilitation: high inactivity (88.4%) barriers, such as fatigue hinder recovery. Professional supervision: only 1%...
<div>Abstract<p><b>Purpose:</b> We aimed to maximize the performance of detecting genetic alterations in lung cancer using high-throughput sequencing for patient-derived xenografts (PDXs).</p><p><b>Experimental Design:</b> undertook an integrated RNA and whole-exome 14 PDXs. focused on functional analysis β2-microglobulin (B2M), a component HLA class-I complex.</p><p><b>Results:</b> identified genes involved various...
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<p>Supplementary methods and materials</p>
<p>Supplementary Figure 1, 2,3 4,5</p>
Background: Familial hypercholesterolemia (FH) is an autosomal dominant genetic disease characterized by elevation in the serum levels of total cholesterol and low-density lipoproteins (LDL-c).Known to be closely related atherosclerotic process, FH can determine development early obstructive lesions different arterial beds.In this context, has also been proposed a risk factor for peripheral (PAD).Objective: This observational cross-sectional study assessed association PAD with other...
Adjuvant emulsions are widely used to enhance the antibody response in animals as immunoglobulin source produce snake antivenoms. We tested performance of four commercial emulsion adjuvants (Montanide, Freund, Carbigen, and Emulsigen-D) an experimental adjuvant (QH-769) horses towards venoms African snakes Bitis arietans, Echis ocellatus, Dendroaspis polylepis Naja nigricollis. Montanide, Freund Carbigen generated highest immune but induced moderate/severe local lesions at site injection. In...
Thirty Aberdeen Angus crossbred steers (281±16 kg) were used to test the effect of finishing feeding system on growth performance, meat quality and fatty acid (FA) profile in intramuscular fat. Steers fed confinement (forage:concentrate ratio 50 : 50; DM basis) or with different levels energy supplementation (0, 0.4, 0.8 1.2% BW) at pasture (Avena strigosa Schreb Lolium multiflorum L.). There no differences between treatments for ADG (average=1.60 kg/day), hot carcass weight (HCW)...
Objective: To evaluate racial differences in healthcare utilization and caregiver burden a culturally diverse population of older adults with dementia.Method: One hundred thirty-three dyads (person dementia, PWD caregiver, CG), at least one emergency department (ED) visit or hospitalization 12 months prior, were enrolled. Independent sample t-tests chi-squared analyses performed to compare groups on CG burden. Mann–Whitney U test was used for item-level analyses, principal component analysis...
Background In high-income temperate countries, the number of hospitalizations for heart failure (HF) and acute myocardial infarction (AMI) increases during winter. This finding has not been fully investigated in low- middle-income countries with tropical subtropical climates. We seasonality HF AMI Sao Paulo (Brazil), largest city Latin America. Methods was a retrospective study using data 76,474 54,561 obtained from public hospitals, January 2008 to April 2015. The average per month winter...
Background Coronary artery calcification (CAC) and atherosclerotic inflammation associate with increased risk of myocardial infarction (MI). Vascular is regulated by osteogenic proteins (OPs). It unknown whether an association exists between CAC plasma OPs if they are affected atherothrombotic inflammation. We tested the inflammatory assessed these biomarkers after MI. Methods Circulating (osteoprotegerin, RANKL, fetuin-A, Matrix Gla protein [MGP]) (C-reactive protein, oxidized-LDL, tumoral...
Elevated B-type natriuretic peptide (BNP) levels following acute myocardial infarction (AMI) are associated with adverse outcomes. The role of serial BNP monitoring after AMI has been poorly investigated. We aimed to evaluate the prognostic value in-hospital measurements in patients.Patients (n=1,924) were retrospectively evaluated. selected patients at least 2 measurements. association between mortality and (earliest, highest follow-up variation measurements) tested multivariate...
Background: The prevalence and clinical outcomes of heart failure with preserved left ventricular ejection fraction after acute myocardial infarction have not been well elucidated.Objective: To analyze the in its association mortality.Methods: Patients (n = 1,474) were prospectively included.Patients without (Killip score 1), > 1 ventricle ≥ 50%), systolic dysfunction < 50%) on admission compared.The between in-hospital mortality was tested adjusted models.Results: Among patients included,...