A5001493194- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Antibiotic Resistance in Bacteria
- COVID-19 diagnosis using AI
- Brucella: diagnosis, epidemiology, treatment
- Pharmaceutical and Antibiotic Environmental Impacts
- Streptococcal Infections and Treatments
- Amoebic Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Parasitic Infections and Diagnostics
- Helicobacter pylori-related gastroenterology studies
- Mobile Health and mHealth Applications
- Infection Control and Ventilation
- Infection Control in Healthcare
- Otolaryngology and Infectious Diseases
- Antibiotics Pharmacokinetics and Efficacy
- Bacteriophages and microbial interactions
- COVID-19 epidemiological studies
- Vagus Nerve Stimulation Research
- Nasal Surgery and Airway Studies
- Advanced Biosensing Techniques and Applications
- Infectious Diseases and Mycology
- Hepatitis C virus research
- Diphtheria, Corynebacterium, and Tetanus
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi
2021-2025
Sağlık Bilimleri Üniversitesi
2016-2024
Ümraniye Eğitim ve Araştırma Hastanesi
2015-2021
Kocaeli Üniversitesi
2007
COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) needed to re-evaluate policies. This study was performed in three pandemic hospitals Istanbul and Kocaeli. Different clusters HCWs were screened for SARS-CoV-2 infection. Seropositivity rate participants evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22...
Background: This study examined the changes in C-reactive protein (CRP), interleukin-6 (IL-6), white blood cell (WBC), neutrophil (NEU), lymphocyte (LYM), and eosinophil (EOS) parameters among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patient groups with Alpha (B.1.1.7), Beta (B.1.351), Delta (B.1.617.2), Omicron (B.1.1.529) variants. Objectives: The present aimed to examine CRP, IL-6, WBC, NEU, LYM, EOS levels patients infected SARS-CoV-2 Methods: Adults over age of 18,...
Background and Objectives: SARS CoV2 has tropism for various tissues, including the respiratory tract, brain, endothe- lium, heart, kidney liver. Neurological symptoms can also be seen in clinical course of disease, anosmia is most common. The main objective our study was to examine urinary amino acid profiles moderately severe patients diagnosed with COVID-19 a positive RT-PCR test try find metabolic changes associated infec- tion. Also, it aimed investigate neuroinhibitory...
Diagnosis of brucellosis basically depends on blood and/or bone marrow culture and demonstration high titer specific antibody or seroconversion in serum. In routine serological diagnosis the disease, after screening with Rose Bengal test, positive samples are studied standart tube agglutination (STA) test serial dilutions. However false negative results can be seen STA due to existence blocking antibodies, this should verified Coombs anti-Brucella (CAB) immunocapture (ICA) tests. recent...
SUMMARY COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) needed to re-evaluate policies. This study was performed in three pandemic hospitals Istanbul and Kocaeli. Different clusters HCWs were screened for SARS-CoV-2 infection. Seropositivity rate participants evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected 119 PCR-confirmed infected HCWs. Of the previously undiagnosed...
Candidemia is the most common serious fungal infection in critically ill patients intensive care units (ICU). It series fourth among bloodstream infectious agents. In this study, candidemia risk analysis was examined COVID 19 and non-COVID during pandemic period.
Candida auris is an opportunistic pathogen that has become widespread in recent years and shows resistance to multiple drugs. The aim of our study was determine the antifungal susceptibilities C. isolates, perform a dendrogram from mass spectra strains obtained matrix-assisted laser desorption ionization-time flight spectrometry order evaluate proteomic similarities geographical clade this by help Multiplex RT-PCR.
Background: It is known that the change in coagulation parameters has an effect on mortality and prognosis COVID-19 patients. The SARS-CoV-2 virus changed with mutations genome of since beginning pandemic, resulting variants have been recorded by World Health Organization. With these variations, clinical severity disease laboratory also changed. Objectives: In this study, we examined changes D-dimer levels, fibrinogen platelet count (PLT), mean volume (MPV) between Alpha (B.1.1.7), Beta...
The aim of the study is to determine in-vitro effects imipenem–tigecycline, imipenem–colistin and tigecycline–colistin against carbapenem-resistant Enterobacteriaceae (CRE) isolates. A total 25 CRE isolates were included study. minimum inhibition concentrations imipenem, colistin-sulphate tigecycline determined with broth dilution method. Synergistic investigated by microdilution checkerboard technique. All resistant whereas 25% colistin tigecycline. Imipenem–colistin, imipenem–tigecycline...
Abstract The gold standard method in the diagnosis of SARS-CoV-2 infection is detection viral RNA nasopharyngeal sample by RT-PCR. Recently, saliva samples has been suggested as an alternative due to being fast, reliable and non-invasive, rather than samples. We compared RT-PCR results nasopharyngeal, oro-nasopharyngeal COVID-19 patients. 98 200 patients were positive analysis performed before hospitalization. In day 0, at least one was 67% Positivity rate 83% for both samples, while it 63%...
Amaç: CMV (sitomegalovirüs) böbrek nakli sonrası en sık görülen viral enfeksiyondur.Akut rejeksiyon, greft yetmezliği, mortalite, fırsatçı enfeksiyonlar, malignite, diabetes ve kardiyovasküler komplikasyon riskini arttırabilir.Nakil profilaktik antiviral tedavi enfeksiyonlarının sıklığını azaltan önemli yaklaşımdır
Upon the emergence of Eris variant in our country, we aimed to develop an RT-qPCR kit detect SARS-CoV-2 variant.
Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syn-drome coronavirus 2 (SARS-CoV-2). The high mortality and morbidity rate its course with wide variety of clinical symptoms indicate that the affects many metabolic pathways. aim our study was to investi-gate effects SARS-CoV-2 evaluating urinary organic acid profile in patients infection. Can metabolites urine guide diagnosis, follow-up, treatment, prognosis COVID-19?
Aim: To develop a new model of acute bacterial rhinosinusitis. Method: We divided guinea pigs into four groups in this study. In the primary group pigs, right nasal cavities animals were vaccinated with Streptococcus pneumoniae suspension. second group, sponge strips saturated sterile saline animals. third suspension The fourth was control which exposed to no intervention. After 7, 14, 28, 35 days from interventions, intranasal cultures obtained, computed tomography (CT) scans imaged all and...
Abstract Hepatitis C virus (HCV) is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma worldwide. HCV has 8 genotypes (GT) 86 subtypes distribution GTs varies based on geographical regions, transmission routes even in cultural groups. The determination viral genotype crucial choosing antiviral treatment, determining the duration therapy, monitoring treatment respose. Since 2014, with usage direct-acting agents (DAAs) infections, cure rate over 95% could be...
Objective: The most important problem in the treatment of nosocomial Acinetobacter baumannii (A. baumannii) infections which is increasingly seen recent years that almost all strains are resistant to many antibiotics, including carbapenems, and extinction antibiotic options be used treatment. This leads clinicians new suggests use combined antibiotics achieve success both multi-drug-resistant A. (MDRAB) as well prevent resistance development. We investigated vitro activity colistin...
The aim of our study is to determine the risk coinfection with COVID-19 due high prevalence viral agents in Istanbul autumn (September, October, and November) winter (December January) investigate effects age, gender, season clinical features on development COVID-19.In routine studies hospital, COVID-19, reverse transcriptase polymerase chain reaction (RTA kit, Turkiye) Multiplex PCR Bio-Fire (Bio Merieux Company, France) methods were studied from nasopharyngeal swab sample data recorded. A...
ABSTRACT Background The new type of Coronavirus infection had become a pandemic in very short period since it was first seen Wuhan. outbreak negative impact on all health care systems throughout the world and overwhelmed diagnostic laboratories as well. During pandemic, handling patient specimens accordance with universal guidelines troublesome WHO, CDC ECDC required cold chain compliance during transporting storing swap samples. Materials methods In this study, we tested performance RT-PCR...
Amaç: Akut gastroenteritler çocuklarda morbidite ve mortalitenin en önemli nedenlerindendir.Rotavirüs tüm dünyada, yenidoğan görülen, gastroenteritlerin etiyolojisinde yer alan viral etkenler arasında bir yere sahiptir.Bu çalışma ile Ümraniye Eğitim Araştırma Hastanesi'ne başvuran çocuk hastalarda, rotavirüse bağlı gastroenterit sıklığının belirlenmesi
DOI:10.5505/bsbd.2015.87587 OZET AMAC: Ellerin ve elle temas eden yuzeylerin mikroorganizma ile kolonizasyonu hastane enfeksiyonlari gelisiminde onemli yer tutmaktadir. Gunumuzde cep telefonlari saglik calisanlarinin gunluk en cok ettikleri gerecler arasinda almaktadir. Calismamizda dokunmatik ekranli telefonlarinin yuzeyinden alinan kulturler ureyen patojenlerin turu belirlenerek, onemi enfeksiyonu rol alip alamayacagi degerlendirildi. YONTEM GERECLER: Cep ekuvyonla ornek alinarak kanli EMB...