A5039422690- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Shoulder Injury and Treatment
- Hip and Femur Fractures
- Shoulder and Clavicle Injuries
- Trauma Management and Diagnosis
- Orthopaedic implants and arthroplasty
- Prostate Cancer Treatment and Research
- TGF-β signaling in diseases
- Metal and Thin Film Mechanics
- Pelvic and Acetabular Injuries
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Dupuytren's Contracture and Treatments
- Hip disorders and treatments
- Sarcoma Diagnosis and Treatment
- Foot and Ankle Surgery
- Trauma and Emergency Care Studies
- Genital Health and Disease
- Connective tissue disorders research
- Sports injuries and prevention
- Musculoskeletal synovial abnormalities and treatments
- Musculoskeletal Disorders and Rehabilitation
- Heterotopic Ossification and Related Conditions
Amsterdam University Medical Centers
2018-2025
University of Amsterdam
2016-2025
Health & Safety in Sports
2023-2024
Amsterdam UMC Location University of Amsterdam
2013-2022
University Hospital of Zurich
2022
University of Colorado Denver
2022
Denver Health Medical Center
2022
Rocky Vista University
2022
University of South Florida
2022
Seoul Medical Center
2017
Computed tomography (CT) is seen as a useful diagnostic modality in preoperative planning for tibial plateau fractures. The purpose of this study was to characterize patterns fractures with use CT mapping. We hypothesized that mapping the would reveal recurrent fragments and fracture lines, including do not fit into Schatzker's original classification.One hundred twenty-seven were retrospectively included study. Fracture lines zones comminution graphically superimposed onto an axial template...
<h3>Background:</h3> Disturbance of the sleep–wake cycle is a characteristic delirium. In addition, changes in melatonin rhythm influence circadian and are associated with We compared effect placebo on incidence duration <h3>Methods:</h3> performed this multicentre, double-blind, randomized controlled trial between November 2008 May 2012 1 academic 2 nonacademic hospitals. Patients aged 65 years or older who were scheduled for acute hip surgery eligible inclusion. received 3 mg evening 5...
Background: In patients managed with plate fixation for the treatment of an olecranon fracture, placement axial intramedullary screw may obstruct bicortical screws in ulnar shaft. To overcome this problem, unicortical can be applied use a contoured locking compression plate. The present study was designed to assess effectiveness method. Methods: Nineteen consecutive acute comminuted fracture were and fixation. Sixteen available follow-up at minimum twelve months after Patient-based outcomes...
The purpose of the present retrospective study was to evaluate results open reduction and internal fixation delayed unions nonunions fractures distal part humerus.Between 1976 2001, fifty-two patients with a union (thirteen patients) or nonunion (thirty-nine humerus were treated along selective elbow joint arthrolysis bone-grafting. average time presentation eighteen months (range, two 192 months) after injury. Thirty-nine had undergone an 1.6 previous operations. There twenty-seven...
Poor bone quality increases the technical difficulty and complications of operative treatment nonunions delayed unions diaphyseal humerus in older patients. Plates with screws that lock to plate (transforming each screw into a fixed blade) are intended improve fixation poor bone. Twenty-four patients (20 women, four men) an average age 72 years (range, 52–86 years) were followed up for minimum 12 months after locking compression osteopenic union (nine patients) or nonunion (15 humerus....
Background: Complex fractures of the distal part humerus can be difficult to characterize on plain radiographs and two-dimensional computed tomography scans. We tested hypothesis that three-dimensional reconstructions scans improve reliability accuracy fracture characterization, classification, treatment decisions. Methods: Five independent observers evaluated thirty consecutive intra-articular for presence five characteristics: a line in coronal plane; articular comminution; metaphyseal...
Lipoma arborescens is a rare intra-articular lesion, characterised by diffuse replacement of the subsynovial tissue mature fat cells, producing prominent villous transformation synovium. The aetiology this benign condition unknown.
Background: Interactions between American and Dutch surgeons suggested differences in prescription habits for pain medication after fracture treatment. Methods: The percentages of 190 [100 hip open reduction interal fixation (ORIF) 90 ankle ORIF] 116 patients (69 ORIF 47 ORIF) receiving inpatient outpatient prescriptions narcotics were retrospectively compared countries, to test the hypothesis that are prescribed more frequently United States as with Netherlands operative Results: Among...
The management of a mangled extremity continues to be matter debate.With modern advances in trauma resuscitation, microvascular tissue transfer, and fracture fixation, severe traumatic injuries that would historically have been amputated are often salvaged.Even if preserving limb is technical possibility, the question raised whether end result will also functional what treatment lead best patient outcome.The road salvage prolonged with significant morbidity, reoperations, financial costs,...
Bone morphogenetic proteins (BMPs) are increasingly being used clinically to enhance fracture repair and healing of non-unions. However, the potential efficacy supraphysiological dosing for clinical results warrants further clarification BMP signaling pathway in human healing. As can be fine-tuned at numerous levels, role BMP-inhibitors has become a major focus. The aim present study was document co-expression BMPs, pSmad 1/5/8, callus Using tissue (n=14) non-unions (n=4) we documented...
Bone-stimulatory therapeutics include bone morphogenetic proteins (e.g. BMP2), parathyroid hormone, and antibody-based suppression of WNT antagonists. Inhibition the epigenetic enzyme enhancer zeste homolog 2 (EZH2) is both anabolic osteoprotective. EZH2 inhibition stimulates key components bone-stimulatory signaling pathways, including BMP2 cascade. Because high costs adverse effects associated with use, here we investigated whether dosing can be reduced by co-treatment inhibitors....
Background: The potential use of bone morphogenetic proteins (BMPs) to promote bone-healing is great interest orthopaedic surgeons. Although the complex mechanism leading from local presence BMP (whether endogenous or exogenous) formation increasingly understood, limited information available as whether BMPs, their receptors, other molecules involved in signal transduction, such Smad1, are present disappear during development fracture nonunions. purpose study was determine, by...
Background: Excellent long-term results have been reported for nonoperative treatment of stable isolated displaced partial articular (Mason 2) fractures the radial head, suggesting that role operative can be questioned. This investigation reports outcome operatively treated Mason 2 head fractures. Methods: Sixteen patients with not associated fracture or dislocation proximal forearm were evaluated an average 22 years (range, 14–30 years) after open reduction and internal fixation screws (11...
To report the long-term results of operative treatment anterior and posterior olecranon fracture-dislocations compare them with recorded fewer than 2 years after surgery.Retrospective case series evaluation.Level I trauma center.Ten patients fracture-dislocation ten were evaluated an average 18 (range, 11 to 28 years) injury. Fifteen had early follow-up available at 14 months 6 24 months) surgery. The age injury was 30 53 years).Treatment included plate screw fixation (11 patients), tension...
Low-profile rigid external fixation can be a helpful adjunct in complex posttraumatic cases as part of staged reconstructive effort. The successful use plates low-profile fixators has been described previously by our institution. locking compression have advocated internal-external fixators, given their angular stable screw fixation. These properties also make them good candidates for plate fixation; we call this technique "supercutaneous plating."
Non-unions of the forearm often cause severe dysfunction as they affect interosseus membrane, elbow and wrist. Treatment these non-unions can be challenging due to poor bone stock, broken hardware, scarring stiffness long-term immobilisation. We retrospectively reviewed a large cohort treated by using uniform surgical approach during period 33 years (1975–2008) in single trauma centre. All were managed following AO-principles compression plate fixation autologous grafting if needed. The...
New concepts in plate fixation have led to an evolution design for olecranon fractures. The purpose of this study was compare the stiffness and strength locking compression (LCP) one-third tubular a cadaveric comminuted fracture model with standardised osteotomy.Five matched pairs elbows were randomly assigned by either contoured LCP combined intramedullary screw unicortical screws or bicortical screws. Construct measured subjecting specimens cyclic loading while measuring gapping at...