A5113884710- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Human Health and Disease
- Gallbladder and Bile Duct Disorders
- Diet, Metabolism, and Disease
- Biomarkers in Disease Mechanisms
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Digestive system and related health
- Aortic aneurysm repair treatments
- Medical and Biological Sciences
- Omental and Epiploic Conditions
- Dermatologic Treatments and Research
- Cardiovascular Disease and Adiposity
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Nutrition, Genetics, and Disease
- Vascular Procedures and Complications
- Hernia repair and management
- Drug-Induced Hepatotoxicity and Protection
- Dermatological and Skeletal Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Intestinal and Peritoneal Adhesions
- Optimism, Hope, and Well-being
- Abdominal Surgery and Complications
Kursk State Medical University
2016-2025
Kursk State University
2016
Ministry of Health of the Russian Federation
2016
Objective. To compare the results of ischemic limb revascularization through superficial and deep femoral arteries in hybrid treatment critical ischemia. Material methods. Treatment outcomes were analyzed 60 patients with lesions infrainguinal TASC grade IIC IID who underwent (balloon angioplasty iliac stenting open artery reconstruction). Two equal groups identified depending on postoperative blood flow: group 1 — flow artery, 2 artery. assessed regarding morbidity clinical status after 6...
The present study was designed to investigate whether the susceptibility acute pancreatitis (AP) attributable polymorphism rs10273639 at PRSS1-PRSS2 locus is dependent on alcohol consumption and cigarette smoking.A total of 603 unrelated Russian individuals including 304 patients with physician-diagnosed AP 299 sex- age-matched healthy controls have been recruited for study. A (-408C>T) genotyped by TaqMan-based assay.A variant allele -408T (P = 0.003) genotypes -408CT plus TT 0.002) were...
Aim of investigation. To estimate the role genetic polymorphism (rs1800566) NAD(F)H quinone oxidoreductase-1 in development acute pancreatitis Russian population. Material and methods. Whole blood samples were received from 349 unrelated AP patients 329 individuals nationality having no gastrointestinal diseases. Mean age was 48.9±13.1 years, mean healthy controls - 47.8±12.1 years. Genotyping NQO1 gene carried out by real-time polymerase chain reaction. Results. The association T/T genotype...
Aim of investigation. To study association interleukin-1 (IL-1) gene (rs16944), interleukin-6 (IL-6) (rs1800795), interleukin-10 (IL-10) (rs1800896) polymorphisms with development acute pancreatitis (AP) in the Russian population. Material and methods. Whole blood samples were received from 297 AP patients 238 healthy controls. Genotyping IL-1 (rs16944) polymorphisms, IL-6 IL-10 was carried out by polymerase chain reaction allele discrimination TaqMan-probes. Results. The genetic...
Relevance of the topic. Acute pancreatitis (OP) is originally an aseptic inflammation pancreas, with possible damage to surrounding tissues and individual organs, as well systems, which third most common after acute appendicitis cholecystitis in number patients. In this regard, experimental model needed further determine tactics management treatment patients varying severity.
 Objective: develop a universal ability control area pancreatic necrosis through use various overlays (distal...
The urgency of acute biliary pancreatitis is due to the increasing number patients suffering from cholelithiasis, as well lack common surgeons’ views on diagnostic and therapeutic algorithms. aim analyze results surgical treatment in accordance with developed medical algorithm. Material methods: 117 at age 20 78 years are analyzed. In 70% pancreatitis, edematous form small-focal pancreonecrosis were found, half examined had destructive forms calculous cholecystitis. Results: a algorithm has...
An important role in the development of chronic pancreatitis (CP) is given to action toxic substances and disruption regulation pro- antioxidant defense processes. One prooxidant enzymes aldehyde oxidase (AOX1), which plays a key metabolism xenobiotics. The aim study was relationship between polymorphism (rs55754655) AOX1 gene CP Russian population. Whole blood samples were collected from 241 patients with 132 healthy individuals. Genotyping performed using PCR method discrimination alleles...
Objective. The radical elimination of extrahepatic biliary tract pathology in choledocholithiasis and acute pancreatitis (ABP) reduces the risk infection eliminates source endogenous intoxication; so, search safe effective techniques for endoscopic papillosphincterotomy (EPT) is important. Purpose: to assess outcomes laser-assisted papillosphincterotomy. Material methods. 288 patients with “wedged” (n = 111) “valve” 177) were divided into two groups depending on EPT technique: control group,...