A5077833960- Drug Transport and Resistance Mechanisms
- Forensic Toxicology and Drug Analysis
- Paraquat toxicity studies and treatments
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Psychedelics and Drug Studies
- Protein Interaction Studies and Fluorescence Analysis
- Analytical Chemistry and Chromatography
- Neuroscience and Neuropharmacology Research
- Cholinesterase and Neurodegenerative Diseases
- Chemotherapy-induced cardiotoxicity and mitigation
- Pharmacological Effects and Toxicity Studies
- Alcohol Consumption and Health Effects
- Free Radicals and Antioxidants
- Pharmacogenetics and Drug Metabolism
- Cardiac Ischemia and Reperfusion
- Electron Spin Resonance Studies
- Computational Drug Discovery Methods
- Biochemical Acid Research Studies
- Mitochondrial Function and Pathology
- Poisoning and overdose treatments
- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
- Vitamin C and Antioxidants Research
- Cancer Treatment and Pharmacology
Universidade do Porto
2016-2025
Rede de Química e Tecnologia
2015-2024
University of Coimbra
2007-2008
National Legal Medicine Institute
2008
Universidade Nova de Lisboa
2008
Universidad de Salamanca
2006
University of Aveiro
1996-2004
Cooperativa de Ensino Superior Politécnico e Universitário
2004
University of Southern California
2004
The discovery of new chemical entities endowed with potent, selective, and reversible monoamine oxidase B inhibitory activity is a clinically relevant subject. Therefore, small library chromone derivatives was synthesized screened toward human isoforms (hMAO-A hMAO-B). structure–activity relationships studies strengthen the importance amide spacer direct linkage carbonyl group to γ-pyrone ring, along presence meta para substituents in exocyclic ring. most potent MAO-B inhibitors were...