A5108036151- Viral Infections and Immunology Research
- CRISPR and Genetic Engineering
- Viral gastroenteritis research and epidemiology
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Hepatitis C virus research
- Animal Disease Management and Epidemiology
University of the Punjab
2021
Lahore University of Management Sciences
2021
National University of Sciences and Technology
2013
Hepatitis C is an inflammatory liver disease caused by the single-stranded RNA (ssRNA) hepatitis virus (HCV). The genetic diversity of and quasispecies produced during replication have resulted in viral resistance to direct-acting antivirals (DAAs) as well impediments vaccine development. recent adaptation CRISPR-Cas alternative antiviral approach has demonstrated degradation nucleic acids eukaryotes. In particular, CRISPR-effector Cas13 enzyme been shown target ssRNA viruses effectively....
Thioglycollate broth with Liver Extract (BQ vaccine medium) was used to produce mass scale yield of Clostridium perfringens Type D. Upon growth in different culture media the OD value bacterial BQ medium, Reinforced Culture Medium (RCM), Cooked Meat (CMM) and Nutrient Broth (NB) 2.260, 2.184, 2.096 1.984 respectively. Mice Lethality result medium equal that RCM while CMM NB had very less lethality. ELISA percentage positivity for Epsilon toxins supernatant at 450 nm wavelength dilution 320...