A5076326228- Health Sciences Research and Education
- Palliative Care and End-of-Life Issues
- Nursing Diagnosis and Documentation
- Chemokine receptors and signaling
- Immunotherapy and Immune Responses
- Multiple Myeloma Research and Treatments
- CAR-T cell therapy research
- HER2/EGFR in Cancer Research
- Healthcare professionals’ stress and burnout
- Immune Cell Function and Interaction
- Health and Well-being Studies
- Clinical practice guidelines implementation
- Optimism, Hope, and Well-being
- Retinoids in leukemia and cellular processes
- Monoclonal and Polyclonal Antibodies Research
- Cell Adhesion Molecules Research
- Chronic Lymphocytic Leukemia Research
- Virus-based gene therapy research
- Immune cells in cancer
- Delphi Technique in Research
- interferon and immune responses
American Nurses Credentialing Center
2022-2025
E Ink (South Korea)
2023-2024
Novartis (United States)
2020
Bristol-Myers Squibb (United States)
2011-2012
Developmental Studies Hybridoma Bank
2012
CXCR4 has been identified as a prognostic marker for acute myeloid leukemia (AML) and other malignancies. We describe the development characterization of fully human antibody to its application therapy AML, non-Hodgkin lymphoma (NHL), chronic lymphoid (CLL), multiple myeloma.Human transgenic mice were immunized with CXCR4-expressing cells, antibodies reactive analyzed apoptosis induction ability interfere CXCL12-induced migration calcium flux. In vivo efficacy was determined in NHL, myeloma...
Mentoring and succession planning in nursing are important elements to ensure continuity, retention, staff engagement, improved patient care outcomes. Both mentoring central tenets of the American Nurses Credentialing Center's (ANCC's) Magnet Recognition Program ® , with organizations required provide evidence formal programs. This month's Magnet® Perspectives explores impact student practicums as a conduit for takes close look at ANCC's unique practicum build competencies develop future...
Over the years, American Nurses Enterprise (ANE) has refined their nursing research priorities to address emerging healthcare challenges, strengthen profession, and advocate for equitable impactful research. Historically, ANE Research Advisory Council focused on 4 pivotal priorities: advancing capacity, fostering interprofessional collaboration, enhancing data structures governance, driving practice-based This column focuses focus areas that represent a significant advancement in shaping...
The aim of this study was to develop research priorities for positive practice environments identified by Pathway Excellence® (Pathway) leaders and appraisers.Identifying achieves 2 goals: 1) advancing agendas that impact improving environments, nurse patient outcomes; 2) informing nursing leaders, researchers, funders potential projects conduct support.Research topics related the 6 standards were developed then rated importance through 3 rounds a Delphi survey at Pathway-designated...
To raise nurses' voices and promote nurse-led research, the American Nurses Credentialing Center's Research Council 2022 Priorities included disseminating a research agenda for practice-based promoting interprofessional encouraging equitable inclusive participation on teams. Expressions of nurses from around world, however, described how organizational constraints financial barriers are real challenges that nurse researchers must face, along with forming interdisciplinary teams to work human...
The American Nurses Association Enterprise (ANA Enterprise) Research Advisory Council plays a vital role in bringing nursing voices together and shaping the dynamic landscape of research. Historically, its priorities have revolved around 4 pivotal research priorities: advancing capacity, promoting interprofessional collaboration, enhancing data structures governance, propelling practice-based In remarkable transition, 2024 Priorities ANA align with vision strategic goals Enterprise. now...
<h3>Background</h3> Natural Killer (NK) cells have garnered increasing interest as potential cellular therapies or targets of biotherapeutic agents due to their ability kill tumor in a non-antigen dependent manner. Hence, measurement NK cell proliferation and/or activation following treatment can serve useful biomarker for assessing the efficacy immunomodulatory therapies. <h3>Methods</h3> We developed novel 13-parameter flow cytometry panel incorporating differentiation (CD) markers...
It is imperative that we listen to our nation's nurses, who have a unique vantage point from their clinical environments. Clinical research nurses greatly contributed studying the delivery of care over years; however, since 2020, COVID-19 has brought unprecedented changes within nursing profession. Each wave pandemic created worrisome landscape where nurse researchers face multiple challenges in implementing and funding practice-based nursing-led projects. To raise nurses' voices promote...
Abstract Background: JULIET, a pivotal phase II trial of Tisa-cel, an anti-CD19 CAR-T cell therapy in pts with r/r LBCL demonstrated durable activity manageable safety profile (Schuster et al., 2021). We sequentially characterized peripheral blood T functionality by immunophenotyping and correlated efficacy endpoints. Methods: Immunophenotypic characterization both non-CAR-T cells was performed flow cytometry 378 samples from 111 collected at enrollment within the first month post Tisa-cel...