While great progress in nanozyme-enabled analytical chemistry has been made, most current nanozyme-based biosensing platforms are based on peroxidase-like nanozymes. However, nanozymes with multienzymatic activities can influence the detection sensitivity and accuracy, while use of unstable hydrogen peroxide (H2O2) a catalytic reaction may result reproducibility challenge sensing signals. We envision that constructing systems by using oxidase-like address these limitations. Herein, we...

In this work, an adaptive learning model predictive control (ALMPC) scheme is proposed for the trajectory tracking of perturbed autonomous ground vehicles (AGVs) subject to input constraints. order estimate unknown system parameter, we propose a set-membership-based parameter estimator based on recursive least-squares (RLS) technique with ensured nonincreasing estimation error. Then, estimated employed in MPC improve prediction accuracy. ALMPC scheme, robustness constraint introduced into...

This article studies integral-type event-triggered model predictive control (MPC) of continuous-time nonlinear systems. An mechanism is proposed by incorporating the integral errors between actual and predicted state sequences, leading to reduced average sampling frequency. Besides, a new improved robustness constraint introduced handle additive disturbance, rendering MPC problem with potentially enlarged initial feasible region. Furthermore, feasibility designed stability closed-loop system...

Natural and artificial enzyme oxygen-generating systems for photodynamic therapy (PDT) are developed tumor treatment, yet they have fallen short of the desired efficacy. Moreover, both enzymes photosensitizers usually need carriers efficient delivery to sites. Here, a self-cascade-enhanced multimodal is by ingeniously integrating PDT with Zn

This article presents a resilient model predictive control (MPC) framework to attenuate adverse effects of denial-of-service (DoS) attacks for cyber-physical systems (CPSs), where the system dynamics is modeled by linear time-invariant system. A DoS attacker targets at blocking controller actuator (C-A) communication channel launching adversarial jamming signals. We show that, in order guarantee exponential stability closed-loop system, several conditions MPC should be satisfied. And these...

This paper considers a target-defense game in an open area with one or two defenders as well intruder. The intruder endeavors to reach the boundary of island, while strive prevent that by capturing through contact. Islands, closed areas, restrict free movement defenders, since defenders—represented USVs—cannot traverse target directly. First, we are concerned barrier, which is winning zones, taking into account impact target. For initial states lying defenders’ zone, there exists strategy...

Rigid three-dimensional scaffolds such as 2-azabicyclo[2.1.1]hexanes (aza-BCHs) and bicyclo[1.1.1]pentanes (BCPs) serve unique saturated isosteres of arenes, offering distinct substitution patterns due to their differing molecular exit vectors. This study introduces a skeletal editing strategy that efficiently transforms multisubstituted aza-BCHs into BCPs via an O-diphenylphosphinylhydroxylamine-promoted N-atom deletion process. method effectively addresses the challenge creating sterically...

This article proposes a model predictive control as secure service (MPCaaSS) framework for cyber–physical systems (CPSs) in the presence of both cyber threats and external disturbances. First, order to take advantage cloud-edge computing, we design double-layer controller architecture by using novel parameterization based on Gaussian radial basis functions. In this architecture, cloud-side optimizes parameters edge-side controller, whereas implements real-time law generated parameters....

Abstract Traditional manual search for large-scale unknown areas is inefficient and hazardous, making multi-UAV collaborative a growing trend. However, existing methods still have shortcomings in complex environments or during sudden failures. This paper proposes adaptive cooperative coverage method based on area dynamic sensing. Firstly, the problem modeled as an optimization problem, sensing set segmentation introduced along with performance metrics.Secondly, perception partitioning used...

Abstract Nanotechnology has significantly facilitated the diagnosis and therapy of inflammatory bowel disease (IBD). To obtain better therapeutic efficacy, a nanoplatform built from polysaccharides metal‐phenolic networks (MPN) is developed here to enhance retention in damaged intestinal region modulate systemic immunological status IBD models. Polysaccharides tragacanth gum (GUM) are coordinated with iron further interact shikonin (Shik) nanocomposite named Shik‐Fe@GUM. Shik‐Fe@GUM...

Immune checkpoint inhibitors that target programmed cell death protein 1 (PD-1) have obtained encouraging results, but a fraction of tumor patients failed to respond anti-PD-1 treatment due the existence multiple immune suppressive elements such as myeloid-derived suppressor cells (MDSCs). Traditional Chinese medicine or natural products from medicinal plants could enhance immunity and may be helpful for cancer immunotherapy. As digestive metabolite cruciferous plants, 3,3'-diindolylmethane...

Abstract This paper considers the problem of a defender agent to guard target area being attacked by hostile agent. There are two different agents‐intruder and here. The purpose is prevent intruder from approaching if possible, catch intruder. As guardian object defender, also obstructs its free movement. Therefore, new geometric method proposed solve problem. Firstly, winning zones constructed for agents using methods. When defender's initial position in zone, can capture zone intruder,...

Tracking a target in cluttered environment is representative application of sensor networks. In this paper, we develop distributed approach to estimate the motion states using noisy measurements. Our method consists two parts. first phase, unscented sigma-point transformation techniques and information filter framework, class algorithms denoted as filters was developed be tracked. These exhibit robustness accuracy for nonlinear dynamic inference while being easily fused filters. second...

This paper investigates the collective rotating motions of a group agents with second-order dynamics in three dimensions. A consensus algorithm for such was proposed by introducing Cartesian Coordinate Coupling and velocity item to an existing protocol. note shows that resulting can be affected network topology, damping gain Euler angle. It is also shown convergence achieved when above certain bound, angle below critical value communication topology has directed spanning tree. Furthermore,...

Nanozymes are functional nanomaterials with enzyme-mimicking activities, which have found wide applications in various fields. Investigation on nanozyme inhibitors not only helps to apply nanozymes a controlled manner but also deepens our insight into the catalysis mechanism. Herein, we report an inorganic ion inhibitor, HCO3–, can significantly inhibit alkaline phosphatase-mimicking activities of Ce6 cluster-based metal–organic framework (Ce-MOF) nanozymes. The inhibition adsorption...

Abstract This paper studies the cooperative tracking control problem of interacted multi‐agent systems (MASs) under undirected communication. Based on differential graphical game theory, MAS is formulated as an infinite horizon game‐theoretic framework, where a multi‐objective optimization designed and then cast into Pareto‐equivalent single‐objective using scalarization method. Necessary sufficient conditions for existence Pareto‐optimal strategy to theoretic are established, it has been...

Topotactic transformation is an emerging strategy for synthesizing materials with exotic functional properties. In this report, instead of producing new crystals related structures, we exploited the topotactic phenomenon to spontaneously produce compositionally diverse nanostructures on transforming substrate. The surface magnetite nanoparticles (Fe3O4 NPs) topotactically transformed into maghemite (γ‐Fe2O3). Benefiting from such oxidation susceptibility ultrasmall Fe3O4 NPs, achieved...