- Child and Adolescent Psychosocial and Emotional Development
- Pharmaceutical studies and practices
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Neurotoxicity Research
- Spinal Cord Injury Research
- Treatment of Major Depression
- Attention Deficit Hyperactivity Disorder
- Cardiomyopathy and Myosin Studies
- Nerve injury and regeneration
- Neuroscience and Neuropharmacology Research
- Laser Applications in Dentistry and Medicine
- Cardiac electrophysiology and arrhythmias
- Mitochondrial Function and Pathology
- Neuroscience and Neural Engineering
- S100 Proteins and Annexins
- Muscle Physiology and Disorders
- Pharmacogenetics and Drug Metabolism
- Acute Ischemic Stroke Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disorders and Treatments
- Cleft Lip and Palate Research
- Thermal Regulation in Medicine
- Bipolar Disorder and Treatment
- Heat shock proteins research
- Skin and Cellular Biology Research
Curtin University
2024-2025
The University of Notre Dame Australia
2018-2023
The University of Western Australia
1989-2014
Sir Charles Gairdner Hospital
2001-2007
Queen Elizabeth II Medical Centre
2001-2007
Perron Institute for Neurological and Translational Science
2006
Red/near-infrared irradiation therapy (R/NIR-IT) delivered by laser or light-emitting diode (LED) has improved functional outcomes in a range of CNS injuries. However, translation R/NIR-IT to the clinic for treatment neurotrauma been hampered lack comparative information regarding degree penetration injury site and optimal parameters different We compared efficacy at 670 nm 830 nm, provided narrow-band LED arrays adjusted produce equal irradiance, four vivo rat models injury: partial optic...
The field of pharmacogenetics (PGx) is experiencing significant growth, with increasing evidence to support its application in psychiatric care, suggesting potential personalize treatment plans, optimize medication efficacy, and reduce adverse drug reactions. However, the perceived utility practicability PGx for youth remains underexplored. This study investigated barriers attitudes Australian young adults towards implementation testing guide antidepressant primary care. Semi-structured...
OBJECTIVE We aimed to determine an effective dose schedule for intravenously administered magnesium, establish its neuroprotective efficacy in both pre- and postischemic treatment paradigms, compare the properties of MgSO4 MgCl2. METHODS Rats that had been subjected bilateral carotid artery occlusion plus hypotension model transient forebrain cerebral ischemia received either loading (LD) 360 μmol/kg only or LD followed by a 48-hour intravenous infusion at 60, 120, 240, 480 μmol/kg/h. For...
Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) motor-related regions cerebral cortex plasticity regrowth projecting into female F344 rat spinal cord after moderate thoracic (T10) contusion injury (SCI). Cortical were transduced with a bi cis tronic adeno-associated viral vector (AAV1) expressing secretory form coupled to mCHERRY...
Tectal tissue from fetal (E15, E18, E20) and newborn (P0) rats was transplanted to the midbrain of rats. Graft survival size decreased with increasing donor age. Host retinal input found in E15, E18 E20 grafts; specific pattern innervation similar for all ages.
Abstract The field of pharmacogenetics (PGx) is experiencing significant growth, with increasing evidence to support its application in psychiatric care, suggesting potential personalise treatment plans, optimise medication efficacy, and reduce adverse drug reactions. However, the perceived utility practicability PGx for youth remains underexplored. This study investigated youth-perceived barriers attitudes towards implementation testing guide antidepressant primary care. Semi-structured...