Sama Bitarafan

ORCID: 0000-0003-1451-7900
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About
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Research Areas
  • Retinoids in leukemia and cellular processes
  • Multiple Sclerosis Research Studies
  • Systemic Lupus Erythematosus Research
  • Psoriasis: Treatment and Pathogenesis
  • Vitamin C and Antioxidants Research
  • Long-Term Effects of COVID-19
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Vitamin D Research Studies
  • Immune Cell Function and Interaction
  • Antioxidant Activity and Oxidative Stress
  • Nausea and vomiting management
  • Migraine and Headache Studies
  • Pharmacological Effects and Toxicity Studies
  • Chemokine receptors and signaling
  • Pregnancy and preeclampsia studies
  • Diet and metabolism studies
  • COVID-19 Clinical Research Studies
  • Infectious Encephalopathies and Encephalitis
  • Anesthesia and Pain Management
  • Metabolism and Genetic Disorders
  • Head and Neck Cancer Studies
  • Parkinson's Disease and Spinal Disorders
  • Nutrition and Health in Aging
  • IL-33, ST2, and ILC Pathways
  • Nuts composition and effects

Imam Khomeini Hospital
2015-2024

Tehran University of Medical Sciences
2015-2024

University of British Columbia
2022-2024

Burnaby Hospital
2022-2024

Georgia Institute of Technology
2024

Fraser Health
2022

This study will evaluate the main hypothesis that supplementation with vitamins A, B, C, D, and E significantly improves severity mortality rate in ICU patients COVID-19. is a randomized, single-blinded, two-arm (1:1 ratio) parallel group clinical trial. We are conducting this COVID-19 admitted to intensive care units at Imam Khomeini Hospital Complex Tehran, Iran. The inclusion criteria as follows: (1) aged between 20 60 years, (2) both male female COVID-19, (3) or definitive diagnosis...

10.1186/s13063-020-04547-0 article EN cc-by Trials 2020-07-06

Because of the effect vitamins on modulating immune system function, we have evaluated supplementation with A, B, C, D, and E in ICU-admitted patients COVID-19.This study was a randomized single-blinded clinical trial which 60 subjects were randomly assigned to two groups. The intervention group (n=30) received vitamins, control did not receive any vitamin or placebo. included 25,000 IU daily 600,000 once during 300 twice E, 500 mg four times one amp B complex for 7 days. At baseline after...

10.1186/s13063-021-05795-4 article EN cc-by Trials 2021-11-14

Multiple sclerosis (MS) is an autoimmune disease whereby myelin sheath of the central nervous system destroyed. Vitamin A known to play a role in immune system. It has been recognized that some metabolites vitamin can be used effectively treat experimental encephalomyelitis (EAE).The effect as retinyl palmitate on T-cell proliferation MS patients.This study double blind clinical trial two test groups over period 6 months.Thirty five multiple patients were divided into groups. One group...

10.4103/0976-3147.102609 article EN Journal of Neurosciences in Rural Practice 2012-09-01

Vitamin A has different functions in the body and after being converted to acid form; it can play many roles immune system regulation. Therefore, this vitamin be used as a supplement treatment of diseases, such cancer autoimmune diseases. is fat-soluble compound its long-term consumption high doses have some adverse effects.The current study aimed investigate possible complications find solutions minimize effects.This was double blind randomized clinical trial. In main study, (as retinyl...

10.5812/ircmj.3480 article EN cc-by-nc Iranian Red Crescent Medical Journal 2013-03-05

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease affecting the central nervous system. Immune cell subsets, notably T helper (Th) 17 and Th1, exert important roles in MS pathogenesis. Whereas, Treg cells modulate process. Calcitriol, active form of vitamin D, curcumin, bioactive compound derived from turmeric, play immunomodulatory effects relevant to disorders, including MS. The objective this study investigate calcitriol Curcumin on Peripheral blood mononuclear (PBMCs)...

10.2174/0118715230293847240314073359 article EN Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2024-04-03

Neurological disease contributes significantly to morbidity and mortality in different ages geographic areas around the world. The purpose of current study was investigate incidence disability-adjusted life years (DALYs) trend neurological Iran during 27 ago. We used data Global Burden Disease (GBD) Study estimate DALYs age groups between 1990 2017. Age were defined 5 including < years, 5-14 15-49 50-69 ≥ 70 years. number 2017 increased from 7.5 million more than 12 rate grew as much 1400...

10.18502/ijnl.v18i3.1637 article EN cc-by-nc Current Journal of Neurology 2019-10-26

Background: Fatigue is a common complaint of patients with multiple sclerosis (MS), adversely affecting their quality life. There lot evidence showing that carnitine deficiency linked to fatigue development and severity in some conditions. This study aimed evaluate the association between free L-carnitine serum levels MS. Methods: case-control included 30 relapsing-remitting MS (RRMS) two age-matched equal-number groups according presence or absence fatigue. was scored using valid...

10.18502/cjn.v22i1.12614 article EN cc-by-nc Current Journal of Neurology 2023-05-03

To compare diet and the modified dietary inflammatory index (mDII) between individuals with pediatric-onset multiple sclerosis (PoMS), monophasic acquired demyelinating syndromes (monoADS), controls. The association diet, mDII, disease status was examined in 131 PoMS/monoADS/controls (38/45/48) using logistic regression. associations PoMS were modest, reaching significance for whole grain intake (adjusted odds ratio, aOR=0.964, 95 % confidence intervals, CI:0.934-0.995) but not mDII...

10.1016/j.msard.2024.105599 article EN cc-by-nc-nd Multiple Sclerosis and Related Disorders 2024-04-04
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