- Oral microbiology and periodontitis research
- Periodontal Regeneration and Treatments
- Oral and gingival health research
- Dental Implant Techniques and Outcomes
- Dental Health and Care Utilization
- Dental materials and restorations
- Oral Health Pathology and Treatment
- Dental Trauma and Treatments
- HIV/AIDS oral health manifestations
- Dental Erosion and Treatment
- Bone and Dental Protein Studies
- Laser Applications in Dentistry and Medicine
- Dental Radiography and Imaging
- Dental Anxiety and Anesthesia Techniques
- Salivary Gland Disorders and Functions
- Endodontics and Root Canal Treatments
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Photodynamic Therapy Research Studies
- Dental Research and COVID-19
- Inflammatory mediators and NSAID effects
- Orthopaedic implants and arthroplasty
- Oral and Maxillofacial Pathology
- dental development and anomalies
- Antifungal resistance and susceptibility
Philipps University of Marburg
2015-2024
Universitätsklinikum Gießen und Marburg
2017-2024
Philips (Germany)
2013-2022
Zentrum für Zahn-, Mund- und Kieferheilkunde Poliklinik für Zahnerhaltung und Parodontologie
2020
Universidad CES
2011
University of Freiburg
2001-2009
University Medical Center
2008
Poliklinik für Zahnerhaltung und Parodontologie
2003
Saarland University
2000-2002
University of Auckland
1996
Abstract Objective The objective of the study is to compare clinical, microbiological and host‐derived effects in non‐surgical treatment initial peri‐implantitis with either adjunctive local drug delivery ( LDD ) or photodynamic therapy PDT after 12 months. Materials Methods Forty subjects peri‐implantitis, that is, pocket probing depths PPD 4–6 mm bleeding on (BoP) radiographic bone loss ≤2 mm, were randomly assigned two groups. All implants mechanically debrided titanium curettes a...
Enterococci have gained significance as the cause of nosocomial infections; they occur food contaminants and also been linked to dental diseases. E. faecalis has a great potential spread virulence well antibiotic resistance genes via horizontal gene transfer. The integration food-borne enterococci into oral biofilm in-vivo observed. Therefore, we investigated determinants 97 isolates from cavity, food, clinical specimens. In addition, phenotypic expression gelatinase cytolysin were tested,...
Abstract Objective To compare the adjunctive clinical effects in non‐surgical treatment of peri‐implantitis with either local drug delivery ( LDD ) or photodynamic therapy PDT ). Material and methods Forty subjects initial peri‐implantitis, i.e. pocket probing depths PPD 4–6 mm concomitant bleeding on BoP marginal bone loss ranging from 0.5 to 2 between reconstruction pre‐screening appointment were randomly assigned two groups. All implants underwent mechanical debridement titanium curettes,...
The formation and composition of dental plaque biofilm in vivo are important factors which influence the development gingivitis, caries periodontitis. Studying vitro models can cause an oversimplification real conditions oral cavity. In this study, bovine enamel slabs were fixed individual acrylic appliance situ to quantify using multiplex fluorescence hybridization (FISH) confocal laser scanning microscopy. Each five oligonucleotide probes used for FISH was specific either eubacteria or one...
Surgery utilizing an enamel matrix protein derivative (EMD) or guided tissue regeneration (GTR) has been shown to promote periodontal regeneration.To evaluate the 10-year results following treatment with EMD, GTR, EMD+GTR, and open flap debridement (OFD).Thirty-eight patients out of initial group 56 participants were treated one four modalities. Results evaluated before surgery, at 1 year, 10 years. Primary outcome variable was CAL change.Treatment EMD yielded a mean gain 3.4+/-1.0 mm...
To investigate the arrangement of biofilms formed in vivo, volunteers wore splints with slabs six different dental materials inserted to collect smooth surface plaque. After 5 d undisturbed plaque accumulation, specimens were vital stained and analyzed by confocal laser scanning microscopy (CLSM) evaluate percentage biofilm microflora (VF percentage). Further parameters area covered (surface coating; SC, %) height (BH, pm). The metals amalgam gold, compomer, as well glass-ionomer cement...
The aim of the present study was to evaluate and compare desensitizing effects an Er:YAG laser (KEY II(R), KaVo, Germany) Dentin Protector (Vivadent, on cervically exposed hypersensitive dentine.A group 30 patients showing a total 104 contralateral pairs caries-free teeth selected randomly allocated in split-mouth design either (1) (80 mJ/pulse, 3 Hz), or (2) application (polyurethane-isocyanate 22.5%; methylenechloride 77.5%) whereat one pair served as untreated control each patient. degree...
Although research in customer satisfaction and service quality has increased enormously the past 10 years, little of this focused on tourist industry. A survey instrument was developed that identified four primary components a tourist's vacation: transportation, accommodation, outdoor activities, attractions. Tourists were inter viewed at Auckland International Airport before leaving New Zealand. They rated their with each various subcomponents. Multiple regres sion results showed attrac...
Abstract Background: Treatment with enamel matrix proteins (EMD) or guided tissue regeneration (GTR) has been shown to enhance periodontal regeneration. However, until now there are limited data on the long‐term results following these treatment modalities. Aim: The aim of present clinical study was 5‐year intrabony defects EMD, GTR, combination EMD and open flap debridement (OFD). Material Methods: Forty‐two patients, each whom displayed one defect a probing depth at least 6 mm, were...
Abstract Background: Regenerative periodontal therapy with a combination of platelet‐rich plasma (PRP)+a natural bone mineral (NBM)+guided tissue regeneration (GTR) has been shown to result in significantly higher probing depth reductions and clinical attachment‐level gains compared treatment open flap debridement alone. However, at present, it is unknown what extent the use PRP may additionally enhance outcome NBM+GTR. Aim: To clinically compare deep intra‐bony defects NBM+PRP+GTR Material...
Background: The purpose of the present study was to compare treatment deep intrabony defects with a combination an enamel matrix protein derivative (EMD) and bioactive glass (BG) BG alone. Methods: Twenty‐eight patients chronic periodontitis, each whom displayed 1 defect, were randomly treated EMD or Soft tissue measurements made at baseline year following therapy. Results: No differences in any investigated parameters observed between 2 groups. Healing uneventful all patients. At after...
Background: The aim of the present study was to compare effectiveness an Er:YAG laser that ultrasonic scaling for non‐surgical periodontal treatment. Methods: Twenty patients with moderate advanced disease were randomly treated in a split‐mouth design single episode subgingival debridement using either device (160 mJ/pulse, 10 Hz) combined calculus detection system fluorescence induced by 655 nm InGaAsP diode radiation (ERL), or instrument (UI). Clinical assessments full‐mouth plaque score...
Abstract Objectives: The aim of this observer‐blind, controlled, three‐cell cross‐over study was to evaluate the influence an amine fluoride/stannous fluoride (Meridol ® , 250 ppm; ASF) and a chlorhexidine mouthrinse (CHX; Chlorhexamed forte 0.2%) compared with water on in situ biofilm growth. Material Methods: After professional toothcleaning seven volunteers had wear special acrylic appliance, which six specimens each were inserted allow build‐up intra‐oral biofilms. rinse twice daily for...
Background: Regenerative periodontal therapy using platelet‐rich plasma (PRP) and different types of bone substitutes with or without guided tissue regeneration (GTR) has been proposed as a modality to enhance the outcome regenerative surgery. However, there are limited data from controlled clinical studies evaluating effect PRP on healing deep intrabony defects treated combination GTR. The aim this study was clinically evaluate beta tricalcium phosphate (β‐TCP) GTR by means...
Background: Regenerative periodontal therapy with a combination of platelet‐rich plasma (PRP) + an anorganic bovine bone mineral (ABBM) guided tissue regeneration (GTR) has been shown to result in significantly higher probing depth reductions and clinical attachment level gains compared treatment open flap debridement (OFD) alone, ABBM or GTR alone. However, there are no data evaluating what extent the use PRP may additionally enhance outcome GTR. This study aimed clinically evaluate effect...
Abstract Oral lichen planus (OLP) is a common, chronic relapsing inflammatory disorder of the mucous membranes, which causes major discomfort. Current treatment includes topical/systemic glucocorticoids, immune modulators and systemic immunosuppressants, may lead to considerable side-effects. The aim this study was determine clinical immunological efficacy photodynamic therapy (PDT) in OLP as an alternative, easy-to-use, safe non-invasive treatment. Twenty patients with were treated PDT...