A5011040618- Nonlinear Dynamics and Pattern Formation
- Neural and Behavioral Psychology Studies
- Neurotransmitter Receptor Influence on Behavior
- Spectroscopy and Quantum Chemical Studies
- Memory and Neural Mechanisms
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Alcohol Consumption and Health Effects
- Photosynthetic Processes and Mechanisms
- Receptor Mechanisms and Signaling
- Quantum chaos and dynamical systems
- Slime Mold and Myxomycetes Research
- Stress Responses and Cortisol
- Nonlinear Photonic Systems
- Spectroscopy and Laser Applications
- Theoretical and Computational Physics
- Genetic Associations and Epidemiology
- Fire effects on ecosystems
- Ecosystem dynamics and resilience
- Neuroscience and Neuropharmacology Research
- Substance Abuse Treatment and Outcomes
- Relativity and Gravitational Theory
- Quantum, superfluid, helium dynamics
- Gambling Behavior and Treatments
- Black Holes and Theoretical Physics
College of Wooster
2016-2024
SUNY Downstate Health Sciences University
2008-2017
Washington University in St. Louis
2010
Columbia University
2010
Rutgers, The State University of New Jersey
2010
Texas Biomedical Research Institute
2010
Indiana University – Purdue University Indianapolis
2010
Indiana University School of Medicine
2010
University of California, San Diego
2010
University of Iowa
2010
Abstract Event‐related brain oscillations (EROs) represent highly heritable neuroelectrical correlates of human perception and cognitive performance that exhibit marked deficits in patients with various psychiatric disorders. We report the results first genome‐wide association study (GWAS) an ERO endophenotype—frontal theta evoked by visual oddball targets during P300 response 1,064 unrelated individuals drawn from a alcohol dependence. Forty‐two SNPs Illumina HumanHap 1 M microarray were...
Endophenotypes reflect more proximal effects of genes than diagnostic categories, hence providing a powerful strategy in searching for involved complex psychiatric disorders. There is strong evidence suggesting the P3 amplitude event-related potential (ERP) as an endophenotype risk alcoholism and other disinhibitory Recent studies demonstrated crucial role corticotropin releasing hormone receptor 1 (CRHR1) environmental stress response ethanol self-administration animal models. The aim...
Event-related oscillations (EROs) represent highly heritable neuroelectric correlates of cognitive processes that manifest deficits in alcoholics and offspring at high risk to develop alcoholism. Theta ERO targets the visual oddball task has been shown be an endophenotype for A family-based genome-wide association study was performed frontal theta phenotype using 634 583 autosomal single nucleotide polymorphisms (SNPs) genotyped 1560 family members from 117 families densely affected by...
We report the formation of stable bound wave packets in a modified Belousov−Zhabotinsky reaction. These densely stacked structures arise from an attractive interaction between oxidation pulses that is not known classical system. The characteristic stacking period increases with initial concentration bromate but decreases cyclohexanedione. Wave can also induce cascades bunching events which internally dense mutually well segregated clusters are formed. For different concentrations, we...
Abstract Recent studies have linked alcoholism with a dysfunctional neural reward system. Although several electrophysiological explored processing in healthy individuals, such alcohol‐dependent individuals are quite rare. The present study examines theta oscillations during abstinent alcoholics. electroencephalogram (EEG) was recorded 38 alcoholics and controls as they performed single outcome gambling task, which involved outcomes of either loss or gain an amount (10 50¢) that bet....
We present experimental results that demonstrate anomalous dispersion in a Belousov−Zhabotinsky system. The reaction is carried out at high concentrations of sulfuric acid and involves 1,4-cyclohexanedione as its organic substrate. unusual behavior this excitable medium induces an attractive interaction between pulses fusion or closed stacking waves. Experimental from quasi-one-dimensional well two-dimensional media are presented. In systems, complex dependence the propagation velocity on...
Several genome-wide association and candidate gene studies have linked chromosome 15q24–q25.1 (a region including the CHRNA5-CHRNA3-CHRNB4 cluster) with alcohol dependence, nicotine dependence smoking-related illnesses such as lung cancer chronic obstructive pulmonary disease. To further examine impact of these genes on development substance use disorders, we tested whether variants within flanking cluster affect transition to daily smoking (individuals who smoked cigarettes 4 or more days...
Background Individuals at high risk to develop alcoholism often manifest neurocognitive deficits as well increased impulsivity. Event-related oscillations (EROs) have been used effectively measure brain (dys)function during cognitive tasks in individuals with and related disorders those these disorders. The current study examines ERO theta power reward processing impulsivity adolescent young adult subjects for alcoholism. Methods EROs were recorded a monetary gambling task (MGT) 12–25 years...
We report experimental results obtained from a chemical reaction-diffusion system in which wave propagation is limited to finite band of wavelengths and no solitary pulses exist. Wave patterns increase their size through repeated annihilation events the frontier pulse that allow succeeding advance farther. A related type dynamics involves stable but slow annihilates subsequent waves front-to-back collisions. These so-called merging give rise an unexpected form spiral nucleation. All these...
We report results from experiments with a pseudo-one-dimensional Belousov-Zhabotinsky reaction that employs 1,4-cyclohexanedione as its organic substrate. This excitable system shows traveling oxidation pulses and pulse trains can undergo complex sequences of propagation failures. Moreover, we present examples for (i) breathing periodic changes in speed size (ii) backfiring near their back repeatedly generate new propagating opposite direction.
The evolution of an excitation front propagating on a nonuniformly curved surface is considered within the framework kinematical model its motion. For case with periodically modulated curvature exact solution shape obtained under assumption sufficiently small deformation. results theoretical consideration are compared experimental data modified Belousov-Zhabotinsky reaction in thin layer.