A5045620538- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Alcohol Consumption and Health Effects
- Multiple Sclerosis Research Studies
- Liver Disease and Transplantation
- Folate and B Vitamins Research
- Diet, Metabolism, and Disease
- Cardiovascular Function and Risk Factors
- Identity, Memory, and Therapy
- Liver physiology and pathology
- Creativity in Education and Neuroscience
- Developmental Biology and Gene Regulation
- MRI in cancer diagnosis
- Congenital limb and hand anomalies
- Hedgehog Signaling Pathway Studies
- Parathyroid Disorders and Treatments
- Endoplasmic Reticulum Stress and Disease
Amsterdam University Medical Centers
2021-2024
University of Amsterdam
2017-2024
Amsterdam Neuroscience
2021
Vrije Universiteit Amsterdam
2021
Amsterdam UMC Location University of Amsterdam
2017
The prevalence and severity of metabolic dysfunction–associated steatotic liver disease (MASLD) are increasing. Physicians who treat patients with MASLD may acknowledge the strong coincidence cardiometabolic disease, including atherosclerotic cardiovascular (asCVD). This raises questions on co-occurrence, causality, need for screening multidisciplinary care in asCVD, vice versa. Here, we review interrelations heart formulate answers to these matters. Epidemiological studies scoring proxies...
The estimated global prevalence and burden of non-alcoholic fatty liver disease (NAFLD) its advanced stage, steatohepatitis (NASH), is increasing. Yet, NAFLD remains largely underdiagnosed. In addition to hepatic morbidity mortality, associated with increased cardiovascular complications, warranting a multidisciplinary approach. Despite rapidly increasing prevalence, knowledge among healthcare workers limited, especially specialists outside the field hepatology gastroenterology.To...
Background & AimsIndividuals with obesity may develop intrapancreatic fat deposition (IPFD) and fatty pancreas disease (FPD). Whether this causes inflammation fibrosis leads to pancreatic dysfunction is less established than for liver damage in metabolic dysfunction-associated steatotic (MASLD). Moreover, the interrelations of FPD MASLD are poorly understood. Therefore, we aimed assess IPFD fibro-inflammation relation function severity individuals MASLD.MethodsSeventy-six participants from...
Background: Suboptimal performance during neuropsychological assessment renders cognitive test results invalid. However, suboptimal has rarely been investigated in multiple sclerosis (MS). Objectives: To investigate potential underlying mechanisms of MS. Methods: Performance validity testing, assessments, neuroimaging, and questionnaires were analyzed 99 MS outpatients with complaints. Based on testing patients classified as valid or invalid performers, based cognitively impaired preserved....
Motivation: The reference standard for diagnosing Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) is invasive liver biopsy. There a need non-invasive diagnostic methods to assess MASLD. Goal(s): goal was determine if multiparametric MRI, including cT1-mapping, MR elastography, intravoxel incoherent motion diffusion-weighted MRI and proton-density fat fraction, can effectively diagnose metabolic-dysfunction-associated steatohepatitis (MASH). Approach: potential of parameters...